PAXIP1 and TECR

Number of citations of the paper that reports this interaction (PMID 21163940)
13

Data Source:
BioGRID (two hybrid)

		PAXIP1	TECR
Gene Name		PAX interacting (with transcription-activation domain) protein 1	trans-2,3-enoyl-CoA reductase
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nuclear Matrix Histone Methyltransferase Complex	Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Endoplasmic Reticulum Membrane
	Molecular Function	Protein Binding	Oxidoreductase Activity, Acting On The CH-CH Group Of Donors
	Biological Process	Positive Regulation Of Histone H3-K36 Methylation Vasculogenesis DNA Repair DNA Recombination Transcription, DNA-templated Response To Ionizing Radiation DNA Damage Response, Signal Transduction By P53 Class Mediator Positive Regulation Of Protein Ubiquitination Positive Regulation Of Histone Acetylation Endothelial Cell Migration Positive Regulation Of Isotype Switching Histone H3-K4 Methylation Positive Regulation Of Histone H3-K4 Methylation Positive Regulation Of Transcription Initiation From RNA Polymerase II Promoter Adipose Tissue Development Chorion Development	Triglyceride Biosynthetic Process Fatty Acid Elongation Long-chain Fatty-acyl-CoA Biosynthetic Process Very Long-chain Fatty Acid Biosynthetic Process Cellular Lipid Metabolic Process Small Molecule Metabolic Process Oxidation-reduction Process
Pathways			Fatty Acyl-CoA Biosynthesis Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Triglyceride Biosynthesis Synthesis of very long-chain fatty acyl-CoAs
Drugs
Diseases
GWAS
Protein-Protein Interactions		91 interactors: A2M APP ATHL1 ATP1B1 ATP1B3 BTBD16 BTBD6 C2orf42 CABYR CATSPERG CBX8 CCNDBP1 CLU COMTD1 CRIPAK CYB5R4 DCP1A DIS3L DNAJA1 DNAJB11 DYNC2H1 ECSIT EIF3I EIF5B EP300 EPB41L3 FAHD1 FAM96B FBLN5 FUCA1 H2AFX HIST1H3A HNRNPLL HSPA14 HSPA4L INTS7 LACTB LOC653602 MAPRE2 MAST1 MRPL33 MT2A MTIF3 ND1 NOS3 NPC2 NUPR1 NXT1 PAGR1 PAX2 PCBP2 PCYT1B PGM1 PIAS1 PIAS2 PKP4 PLCD1 PML POM121 PPHLN1 PPIA PPP2R5C PRDX6 PSMA6 RNF32 RPA1 RPL12 RPS20 RPS27A SCAMP5 SCCPDH SELV SH3GL2 SMAD2 SNX3 SOX30 SPAG4 SPATA18 SUGT1 SUZ12 TCN2 TECR TM2D3 TMEM120A TP53BP1 TRAPPC8 UMPS WDR48 ZBTB8A ZNF251 ZNF280B	3 interactors: HACD2 NOS3 PAXIP1
Entrez ID		22976	9524
HPRD ID		08491	17076
Ensembl ID		ENSG00000157212	ENSG00000099797
Uniprot IDs		Q6ZW49	Q9NZ01
PDB IDs		3SQD	2DZJ
Enriched GO Terms of Interacting Partners?		Response To Stress Cellular Localization Signal Transduction By P53 Class Mediator Cellular Nitrogen Compound Metabolic Process Posttranscriptional Regulation Of Gene Expression Nitrogen Compound Metabolic Process Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Protein Localization Cellular Response To DNA Damage Stimulus Intracellular Receptor Signaling Pathway Gene Expression Spermatogenesis Heterocycle Metabolic Process Male Gamete Generation Nucleobase-containing Compound Metabolic Process Cellular Aromatic Compound Metabolic Process Metabolic Process Cellular Response To Stress Blood Coagulation DNA Damage Checkpoint Hemostasis Protein Stabilization Translational Initiation Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of Body Fluid Levels Cellular Metabolic Process Reproductive Process Establishment Of Localization In Cell Positive Regulation Of Potassium Ion Import DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest RNA Metabolic Process Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Signal Transduction Involved In DNA Damage Checkpoint Response To Stimulus Signal Transduction Involved In Cell Cycle Checkpoint Gamete Generation Regulation Of Protein Ubiquitination Positive Regulation Of Sodium Ion Export From Cell Sexual Reproduction Regulation Of Cellular Protein Metabolic Process Catabolic Process Mitotic Cell Cycle Process Viral Process Platelet Degranulation Regulation Of Protein Stability Positive Regulation Of Cell Cycle Process Mitotic G1 DNA Damage Checkpoint Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Positive Regulation Of Cell Cycle Arrest	Endothelial Cell Migration Epithelial Cell Migration Epithelium Migration Positive Regulation Of Histone H3-K36 Methylation Ameboidal-type Cell Migration Smooth Muscle Hyperplasia Smooth Muscle Adaptation Regulation Of Systemic Arterial Blood Pressure By Endothelin Negative Regulation Of Muscle Hyperplasia Regulation Of The Force Of Heart Contraction By Chemical Signal Blood Vessel Morphogenesis Arginine Catabolic Process Chorion Development Regulation Of Cell Activation Very Long-chain Fatty Acid Biosynthetic Process Positive Regulation Of Guanylate Cyclase Activity Blood Vessel Development Ovulation From Ovarian Follicle Vasculature Development Fatty Acid Elongation Nitric Oxide Biosynthetic Process Positive Regulation Of Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Positive Regulation Of Histone H3-K4 Methylation Nitric Oxide Mediated Signal Transduction Positive Regulation Of DNA-templated Transcription, Initiation Positive Regulation Of CGMP Biosynthetic Process Negative Regulation Of Platelet Activation Positive Regulation Of CGMP Metabolic Process Arginine Metabolic Process Positive Regulation Of MRNA Catabolic Process Ovulation Positive Regulation Of Histone Acetylation Negative Regulation Of Potassium Ion Transport Regulation Of DNA-templated Transcription, Initiation Regulation Of CGMP Biosynthetic Process Regulation Of Histone H3-K4 Methylation Positive Regulation Of Peptidyl-lysine Acetylation Positive Regulation Of Isotype Switching Positive Regulation Of Protein Acetylation Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Nitric Oxide Metabolic Process Cell Migration Reactive Nitrogen Species Metabolic Process Regulation Of The Force Of Heart Contraction Regulation Of Platelet Activation Regulation Of CGMP Metabolic Process Cardiovascular System Development Histone H3-K4 Methylation Positive Regulation Of Vasodilation
Tagcloud ?		amnion axial bmp2 chorion chorionic cognate ectoderm endodermal extraembryonic fail gastrulation mesodermal methyltransferases mll3 mll4 neuroectodermal originally pa1 pagr1 pagr1a patterning predominately pregastrulation rotation sac somite visceral yolk
Tagcloud (Difference) ?		amnion axial bmp2 chorion chorionic cognate ectoderm endodermal extraembryonic fail gastrulation mesodermal methyltransferases mll3 mll4 neuroectodermal originally pa1 pagr1 pagr1a patterning predominately pregastrulation rotation sac somite visceral yolk
Tagcloud (Intersection) ?