TECR and GOLT1A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TECR	GOLT1A
Description		trans-2,3-enoyl-CoA reductase	golgi transport 1A
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane	Golgi Cis Cisterna Golgi Membrane Nuclear Envelope Cytoplasm Endoplasmic Reticulum Golgi Apparatus Trans-Golgi Network Cytosol Endomembrane System Membrane
	Molecular Function	Protein Binding Oxidoreductase Activity Oxidoreductase Activity, Acting On The CH-CH Group Of Donors Very-long-chain Fatty Acyl-CoA Dehydrogenase Activity Very-long-chain Enoyl-CoA Reductase Activity	Protein Binding
	Biological Process	Lipid Metabolic Process Fatty Acid Metabolic Process Fatty Acid Biosynthetic Process Sphingolipid Metabolic Process Fatty Acid Elongation Long-chain Fatty-acyl-CoA Biosynthetic Process Very Long-chain Fatty Acid Biosynthetic Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Protein Transport Vesicle-mediated Transport Retrograde Transport, Endosome To Golgi
Pathways		Synthesis of very long-chain fatty acyl-CoAs
Drugs
Diseases
GWAS		Femur bone mineral density x serum urate levels interaction ( 34046847)	Metabolite levels ( 23823483) Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)
Interacting Genes		33 interacting genes: AQP6 ARL13B CD79A CLDN5 CRB3 CREB3 CREB3L1 ELOVL4 ERGIC3 FAM209A FBXO7 FKBP7 GET1 GOLT1A HACD1 JAGN1 MMGT1 MUC1 NOS3 PAXIP1 PGRMC2 PTEN RETREG3 SAR1A SLC10A6 SLC18A1 SLC35H1 SLC71A2 SLC7A14 STING1 STOM TFAM VMA21	26 interacting genes: ABHD16A AGPAT3 AQP6 C8A CCDC167 CLDND2 COX20 CPT1B FAXDC2 GPR152 GYPA HSD17B11 MGLL MSMO1 NAT8 NDUFA3 NRM OTULINL PLLP RNF24 SLC30A2 SLC35H1 TECR TIMM23 TMEM242 UBE2J1
Entrez ID		9524	127845
HPRD ID		17076	13465
Ensembl ID		ENSG00000099797	ENSG00000174567
Uniprot IDs		B3KSQ1 B4DR74 Q9NZ01	Q6ZVE7
PDB IDs		2DZJ
Enriched GO Terms of Interacting Partners?		Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Negative Regulation Of Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Apoptotic Signaling Pathway Schmidt-Lanterman Incisure Negative Regulation Of Cell Cycle G1/S Phase Transition Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Very Long-chain Fatty Acid Biosynthetic Process Fatty Acid Elongation Protein Binding Tail-anchored Membrane Protein Insertion Into ER Membrane Regulation Of Intrinsic Apoptotic Signaling Pathway	Membrane C-4 Methylsterol Oxidase Activity Monoacylglycerol Catabolic Process Lipid Metabolic Process Lipid Biosynthetic Process Endoplasmic Reticulum Membrane Monoacylglycerol Lipase Activity Steroid Biosynthetic Process Mitochondrial Inner Membrane Phosphatidylcholine Lysophospholipase Activity Lipid Catabolic Process Acylglycerol Catabolic Process Fatty Acid Metabolic Process Nitrate Transmembrane Transporter Activity Acyltransferase Activity Zinc Ion Import Into Zymogen Granule Zinc Ion Import Into Mitochondrion Zinc Ion Import Into Secretory Vesicle L-cysteine-S-conjugate N-acetyltransferase Activity Protein Binding Modified Amino Acid Metabolic Process Sterol Biosynthetic Process
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