NMD3 and YTHDF3

Number of citations of the paper that reports this interaction (PubMedID 34133714)
84

Data Source:
BioGRID (two hybrid)

		NMD3	YTHDF3
Description		NMD3 ribosome export adaptor	YTH N6-methyladenosine RNA binding protein F3
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Membrane	P-body Cytoplasm Cytosol Cytoplasmic Stress Granule
	Molecular Function	RNA Binding Protein-macromolecule Adaptor Activity Ribosomal Large Subunit Binding	RNA Binding MRNA Binding Protein Binding Ribosome Binding N6-methyladenosine-containing RNA Reader Activity
	Biological Process	Ribosomal Large Subunit Export From Nucleus Protein Transport Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of Protein Localization To Nucleolus	Stress Granule Assembly Regulation Of MRNA Stability Positive Regulation Of Translation Positive Regulation Of Translational Initiation Negative Regulation Of Type I Interferon-mediated Signaling Pathway MRNA Destabilization Organelle Assembly Regulation Of Trophoblast Cell Migration
Pathways
Drugs
Diseases
GWAS		Chronotype ( 30696823) Interleukin-10 levels ( 22205395) Morning person ( 30696823) Post bronchodilator FEV1 ( 26634245) Post bronchodilator FEV1/FVC ratio ( 26634245)	Adult body size ( 32376654) Body size at age 10 ( 32376654) Breakfast cereal skipping frequency ( 31190057) Breakfast skipping ( 31190057) Chronotype ( 30696823) HDL cholesterol levels ( 32203549) Myocardial infarction ( 26708285) Schizophrenia ( 33169155) Smoking behaviour (cigarettes smoked per day) ( 30679032) Systolic blood pressure ( 30224653) Triglyceride levels ( 32203549)
Interacting Genes		4 interacting genes: CSNK2A1 LNX2 XPO1 YTHDF3	17 interacting genes: ALG13 ANKHD1 CPSF7 CTTN DMRTB1 EXOSC5 FAF1 LARP4 NMD3 PRRC2B QKI RBFOX2 RBM22 RPS21 SF1 SNRPA ZDHHC17
Entrez ID		51068	253943
HPRD ID		13026	08106
Ensembl ID		ENSG00000169251	ENSG00000185728
Uniprot IDs		C9JA08 Q96D46	A0A024R7W5 A0A087WY31 B4DPX9 Q7Z739 Q8NA80
PDB IDs		6LQM 6LSR 6LU8	6ZOT 8BS5 8BS6
Enriched GO Terms of Interacting Partners?		Regulation Of Translational Initiation Protein Localization To Organelle Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Kinase CK2 Complex Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Symbiont-mediated Disruption Of Host Cell PML Body Positive Regulation Of Aggrephagy Organelle Assembly Annulate Lamellae Response To Triglyceride Cellular Response To Triglyceride Tooth Eruption Articular Cartilage Development Growth Plate Cartilage Chondrocyte Differentiation Negative Regulation Of Non-canonical Wnt Signaling Pathway Bone Mineralization Involved In Bone Maturation Response To Inositol Cartilage Homeostasis Receptor Localization To Non-motile Cilium Protein Stabilization Cellular Response To Salt Ribosomal Small Subunit Export From Nucleus Ribosomal Large Subunit Export From Nucleus Odontoblast Differentiation Chondrocyte Differentiation Involved In Endochondral Bone Morphogenesis Protein Localization To Ciliary Membrane Wnt Signaling Pathway Membraneless Organelle Assembly Double-strand Break Repair Via Classical Nonhomologous End Joining Intracellular Transport Ribosomal Subunit Export From Nucleus Protein Localization To Non-motile Cilium Growth Plate Cartilage Development 9+0 Non-motile Cilium Osteoblast Proliferation Regulation Of Wnt Signaling Pathway Nuclear Export Signal Receptor Activity N6-methyladenosine-containing RNA Reader Activity Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA Aggrephagy Protein Targeting To Vacuole Involved In Autophagy Regulation Of Protein Catabolic Process Regulation Of Protein Stability Negative Regulation Of Signal Transduction MRNA Methylguanosine-cap Decapping Regulation Of Proteolysis Intraciliary Anterograde Transport Regulation Of Trophoblast Cell Migration Intraciliary Transport Particle B	RNA Binding Nucleic Acid Binding RNA Processing MRNA Metabolic Process MRNA Processing RNA Splicing RNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA 3'-end Processing MRNA Cis Splicing, Via Spliceosome MRNA Binding Cytosolic Small Ribosomal Subunit Endonucleolytic Cleavage To Generate Mature 3'-end Of SSU-rRNA From (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Nucleic Acid Metabolic Process Spliceosomal Complex Gamma-glutamyl-peptidase Activity Regulation Of RNA Splicing Internal N(7)-methylguanine-containing RNA Reader Activity Perforant Pathway To Dendrate Granule Cell Synapse Methionine Adenosyltransferase Regulator Activity N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase Activity Macromolecule Metabolic Process
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