IGSF5 and LNX2

Number of citations of the paper that reports this interaction (PMID 16832352)
5

Data Source:
BioGRID (two hybrid)

		IGSF5	LNX2
Gene Name		immunoglobulin superfamily, member 5	ligand of numb-protein X 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Cell-cell Junction Tight Junction Cell Surface Integral Component Of Membrane Neuron Projection Neuronal Cell Body
	Molecular Function	PDZ Domain Binding	Protein Binding Zinc Ion Binding PDZ Domain Binding
	Biological Process	Single Organismal Cell-cell Adhesion Regulation Of Neurogenesis	Protein Homooligomerization
Pathways
Drugs
Diseases
GWAS		Coronary heart disease ( 21347282)	Large B-cell lymphoma ( 21471979)
Protein-Protein Interactions		3 interactors: LNX1 LNX2 MAGI1	17 interactors: CBX4 CXADR HOXA1 IGSF5 LNX1 MDGA1 NUMB PDZRN3 PDZRN4 PKDREJ RLIM RNF138 SHISA2 UBE2I UBE2T UBE2Z USP2
Entrez ID		150084	222484
HPRD ID		19125	10042
Ensembl ID		ENSG00000183067	ENSG00000139517
Uniprot IDs		Q9NSI5	Q8N448
PDB IDs			2VWR
Enriched GO Terms of Interacting Partners?		Protein Complex Assembly Protein Homooligomerization Cellular Component Assembly Protein Oligomerization Negative Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of Sodium Ion Transport Negative Regulation Of ERK1 And ERK2 Cascade Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Neuron Death Regulation Of Sodium Ion Transport	Protein Modification By Small Protein Conjugation Protein Ubiquitination Cellular Protein Modification Process Protein Sumoylation Cellular Protein Metabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Optokinetic Behavior Abducens Nerve Formation Random Inactivation Of X Chromosome Positive Regulation Of SUMO Transferase Activity Protein Catabolic Process Facial Nucleus Development Positive Regulation Of Polarized Epithelial Cell Differentiation Protein Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Rhombomere 4 Development Semicircular Canal Formation Cellular Macromolecule Catabolic Process Rhombomere 3 Development Rhombomere 5 Development Neuroblast Division In Subventricular Zone Protein K27-linked Ubiquitination Protein K29-linked Ubiquitination AV Node Cell To Bundle Of His Cell Communication
Tagcloud ?			amplicons aneuploidy behind candidates colorectal copy crc dis3 downregulated drivers gains gpr180 imbalances klf5 landscape mapping notch nupl1 offering oncogene polr1d pomp profiling rnai silencing slc7a1 tcf7l2 unfinished wnt
Tagcloud (Difference) ?			amplicons aneuploidy behind candidates colorectal copy crc dis3 downregulated drivers gains gpr180 imbalances klf5 landscape mapping notch nupl1 offering oncogene polr1d pomp profiling rnai silencing slc7a1 tcf7l2 unfinished wnt
Tagcloud (Intersection) ?