PKDREJ and LNX2

Number of citations of the paper that reports this interaction (PMID 22889411)
1

Data Source:
BioGRID (two hybrid)

		PKDREJ	LNX2
Gene Name		polycystin (PKD) family receptor for egg jelly	ligand of numb-protein X 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Membrane Integral Component Of Membrane
	Molecular Function	Calcium Channel Activity Calcium Ion Binding	Protein Binding Zinc Ion Binding PDZ Domain Binding
	Biological Process	Acrosome Reaction Detection Of Mechanical Stimulus Regulation Of Acrosome Reaction Calcium Ion Transmembrane Transport	Protein Homooligomerization
Pathways
Drugs
Diseases
GWAS			Large B-cell lymphoma ( 21471979)
Protein-Protein Interactions		2 interactors: LNX1 LNX2	17 interactors: CBX4 CXADR HOXA1 IGSF5 LNX1 MDGA1 NUMB PDZRN3 PDZRN4 PKDREJ RLIM RNF138 SHISA2 UBE2I UBE2T UBE2Z USP2
Entrez ID		10343	222484
HPRD ID		05239	10042
Ensembl ID		ENSG00000130943	ENSG00000139517
Uniprot IDs		Q9NTG1	Q8N448
PDB IDs			2VWR
Enriched GO Terms of Interacting Partners?		Protein Homooligomerization Protein Oligomerization Protein Complex Assembly Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Cellular Component Assembly	Protein Modification By Small Protein Conjugation Protein Ubiquitination Cellular Protein Modification Process Protein Sumoylation Cellular Protein Metabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Optokinetic Behavior Abducens Nerve Formation Random Inactivation Of X Chromosome Positive Regulation Of SUMO Transferase Activity Protein Catabolic Process Facial Nucleus Development Positive Regulation Of Polarized Epithelial Cell Differentiation Protein Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Rhombomere 4 Development Semicircular Canal Formation Cellular Macromolecule Catabolic Process Rhombomere 3 Development Rhombomere 5 Development Neuroblast Division In Subventricular Zone Protein K27-linked Ubiquitination Protein K29-linked Ubiquitination AV Node Cell To Bundle Of His Cell Communication
Tagcloud ?		accelerated acrosome advantages competition constitute copulatory cricetidae cricetids divergence episodes evolution evolutionary fertilization influencing mass muridae participates primates proxy reproductive rodents selection sexual situations sperm steps testes testis undergo	amplicons aneuploidy behind candidates colorectal copy crc dis3 downregulated drivers gains gpr180 imbalances klf5 landscape mapping notch nupl1 offering oncogene polr1d pomp profiling rnai silencing slc7a1 tcf7l2 unfinished wnt
Tagcloud (Difference) ?		accelerated acrosome advantages competition constitute copulatory cricetidae cricetids divergence episodes evolution evolutionary fertilization influencing mass muridae participates primates proxy reproductive rodents selection sexual situations sperm steps testes testis undergo	amplicons aneuploidy behind candidates colorectal copy crc dis3 downregulated drivers gains gpr180 imbalances klf5 landscape mapping notch nupl1 offering oncogene polr1d pomp profiling rnai silencing slc7a1 tcf7l2 unfinished wnt
Tagcloud (Intersection) ?