FANCF and FANCG

Number of citations of the paper that reports this interaction (PMID 11063725)
26

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		FANCF	FANCG
Gene Name		Fanconi anemia, complementation group F	Fanconi anemia, complementation group G
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Fanconi Anaemia Nuclear Complex	Nucleoplasm Nucleolus Cytoplasm Mitochondrion Plasma Membrane Fanconi Anaemia Nuclear Complex
	Molecular Function	Molecular_function Ubiquitin-protein Transferase Activity Protein Binding	Damaged DNA Binding Protein Binding
	Biological Process	Ovarian Follicle Development DNA Repair Spermatogenesis Biological_process Protein Ubiquitination	Cell Cycle Checkpoint Ovarian Follicle Development DNA Repair Mitochondrion Organization Spermatid Development Response To Radiation
Pathways		Fanconi Anemia pathway	Fanconi Anemia pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: FANCA FANCC FANCE FANCG HES1 MARK3 OLFM2	22 interactors: BRCA2 BRCC3 CAPN1 CDK1 CYP19A1 CYP2E1 ERCC4 FANCA FANCC FANCE FANCF FTSJ3 GABPB1 HES1 KRT19 PSMB1 RTN2 SAMD3 UIMC1 USHBP1 XRCC3 ZBED1
Entrez ID		2188	2189
HPRD ID		04589	04262
Ensembl ID		ENSG00000183161	ENSG00000221829
Uniprot IDs		A3KME0 Q9NPI8	O15287 Q53XM5
PDB IDs		2IQC
Enriched GO Terms of Interacting Partners?		DNA Repair Developmental Process Involved In Reproduction Cellular Response To DNA Damage Stimulus DNA Metabolic Process Single Organism Reproductive Process Reproductive Process Reproductive Structure Development Negative Regulation Of Stomach Neuroendocrine Cell Differentiation Negative Regulation Of Pancreatic A Cell Differentiation Pharyngeal Arch Artery Morphogenesis Lateral Inhibition Reproductive System Development Female Gonad Development Development Of Primary Female Sexual Characteristics Cellular Response To Stress Negative Regulation Of Forebrain Neuron Differentiation Negative Regulation Of Auditory Receptor Cell Differentiation Inhibition Of Neuroepithelial Cell Differentiation Negative Regulation Of Pro-B Cell Differentiation Negative Regulation Of Inner Ear Receptor Cell Differentiation Auditory Receptor Cell Fate Determination Trochlear Nerve Development Ascending Aorta Morphogenesis Positive Regulation Of Mitotic Cell Cycle, Embryonic Oculomotor Nerve Development Regulation Of Pro-B Cell Differentiation Regulation Of Auditory Receptor Cell Differentiation STAT Protein Import Into Nucleus Gonad Development Regulation Of Forebrain Neuron Differentiation Cardiac Neural Crest Cell Development Involved In Outflow Tract Morphogenesis Regulation Of Mitotic Cell Cycle, Embryonic Regulation Of Timing Of Neuron Differentiation Forebrain Radial Glial Cell Differentiation Comma-shaped Body Morphogenesis Development Of Primary Sexual Characteristics Common Bile Duct Development Metanephric Nephron Tubule Morphogenesis Midbrain-hindbrain Boundary Morphogenesis Renal Interstitial Fibroblast Development Germ Cell Development S-shaped Body Morphogenesis Protein Complex Assembly Reproduction Negative Regulation Of Hematopoietic Progenitor Cell Differentiation Neuron Fate Determination Auditory Receptor Cell Fate Commitment Negative Regulation Of Epidermal Cell Differentiation Positive Regulation Of Astrocyte Differentiation Radial Glial Cell Differentiation	Cellular Response To DNA Damage Stimulus DNA Repair DNA Metabolic Process Cellular Response To Stress Double-strand Break Repair Developmental Process Involved In Reproduction Heterocycle Metabolic Process Histone H2A K63-linked Deubiquitination Reproductive Structure Development Reproductive System Development Positive Regulation Of Mitotic Cell Cycle Single Organism Reproductive Process G2 DNA Damage Checkpoint Positive Regulation Of Cell Cycle Response To Stress Cellular Nitrogen Compound Metabolic Process Reproductive Process DNA Damage Checkpoint Nucleobase-containing Compound Metabolic Process Nitrogen Compound Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Mitotic Cell Cycle Cell Cycle Checkpoint Double-strand Break Repair Via Homologous Recombination Recombinational Repair Nucleotide-excision Repair Cell Cycle Cellular Response To Stimulus Protein K63-linked Deubiquitination Female Gonad Development Development Of Primary Female Sexual Characteristics Histone Deubiquitination Cellular Metabolic Process Reproduction Cell Cycle Process Response To Stimulus Response To Ionizing Radiation Positive Regulation Of DNA Metabolic Process Histone Modification Response To X-ray Meiotic Nuclear Division Muscle Cell Development Positive Regulation Of DNA Repair Response To Radiation Response To Reactive Oxygen Species Meiotic Cell Cycle Regulation Of Cell Cycle Gonad Development Nucleotide-excision Repair Involved In Interstrand Cross-link Repair Negative Regulation Of Stomach Neuroendocrine Cell Differentiation
Tagcloud ?		bloom brca1 centrosome circumference connected coregulated coregulation divergent e2f e2f3 exploiting fanca fanconi fluctuations govern id jointly mesh microcephaly networks predisposition rb1 retinoblastoma silico subcellular subnetwork upregulation vital	24h 300mum 513a 5p abp aminobiphenyl array arrays arylamine bioinformatic carcinogen comet damage deregulation eventually exo1 hepg2 lig1 mirna mirnas parallel pcna pcr qrt rad18 repair ung validated xrcc2
Tagcloud (Difference) ?		bloom brca1 centrosome circumference connected coregulated coregulation divergent e2f e2f3 exploiting fanca fanconi fluctuations govern id jointly mesh microcephaly networks predisposition rb1 retinoblastoma silico subcellular subnetwork upregulation vital	24h 300mum 513a 5p abp aminobiphenyl array arrays arylamine bioinformatic carcinogen comet damage deregulation eventually exo1 hepg2 lig1 mirna mirnas parallel pcna pcr qrt rad18 repair ung validated xrcc2
Tagcloud (Intersection) ?