FANCG and GABPB1

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		FANCG	GABPB1
Gene Name		Fanconi anemia, complementation group G	GA binding protein transcription factor, beta subunit 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Nucleolus Cytoplasm Mitochondrion Plasma Membrane Fanconi Anaemia Nuclear Complex	Nucleus Nucleoplasm
	Molecular Function	Damaged DNA Binding Protein Binding	Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Transcription Regulatory Region DNA Binding Protein Heterodimerization Activity
	Biological Process	Cell Cycle Checkpoint Ovarian Follicle Development DNA Repair Mitochondrion Organization Spermatid Development Response To Radiation	Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Organelle Organization Mitochondrion Organization Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways		Fanconi Anemia pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		22 interactors: BRCA2 BRCC3 CAPN1 CDK1 CYP19A1 CYP2E1 ERCC4 FANCA FANCC FANCE FANCF FTSJ3 GABPB1 HES1 KRT19 PSMB1 RTN2 SAMD3 UIMC1 USHBP1 XRCC3 ZBED1	23 interactors: ATF1 BAI2 CIC FAM90A1 FANCG GABPA HCFC1 IL16 LMO1 LMO3 LMO4 MAGEB18 POGZ RBM11 RSPH14 RYBP SNRPA SNRPB2 TDRD7 TRAF2 USO1 YAF2 ZDHHC17
Entrez ID		2189	2553
HPRD ID		04262	15975
Ensembl ID		ENSG00000221829	ENSG00000104064
Uniprot IDs		O15287 Q53XM5	Q06547
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Response To DNA Damage Stimulus DNA Repair DNA Metabolic Process Cellular Response To Stress Double-strand Break Repair Developmental Process Involved In Reproduction Heterocycle Metabolic Process Histone H2A K63-linked Deubiquitination Reproductive Structure Development Reproductive System Development Positive Regulation Of Mitotic Cell Cycle Single Organism Reproductive Process G2 DNA Damage Checkpoint Positive Regulation Of Cell Cycle Response To Stress Cellular Nitrogen Compound Metabolic Process Reproductive Process DNA Damage Checkpoint Nucleobase-containing Compound Metabolic Process Nitrogen Compound Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Mitotic Cell Cycle Cell Cycle Checkpoint Double-strand Break Repair Via Homologous Recombination Recombinational Repair Nucleotide-excision Repair Cell Cycle Cellular Response To Stimulus Protein K63-linked Deubiquitination Female Gonad Development Development Of Primary Female Sexual Characteristics Histone Deubiquitination Cellular Metabolic Process Reproduction Cell Cycle Process Response To Stimulus Response To Ionizing Radiation Positive Regulation Of DNA Metabolic Process Histone Modification Response To X-ray Meiotic Nuclear Division Muscle Cell Development Positive Regulation Of DNA Repair Response To Radiation Response To Reactive Oxygen Species Meiotic Cell Cycle Regulation Of Cell Cycle Gonad Development Nucleotide-excision Repair Involved In Interstrand Cross-link Repair Negative Regulation Of Stomach Neuroendocrine Cell Differentiation	RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Cellular Nitrogen Compound Metabolic Process Transcription, DNA-templated Regulation Of RNA Metabolic Process RNA Biosynthetic Process Nitrogen Compound Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Positive Regulation Of Glucocorticoid Receptor Signaling Pathway Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Gene Expression Positive Regulation Of Transcription From RNA Polymerase II Promoter TRIF-dependent Toll-like Receptor Signaling Pathway Positive Regulation Of Cellular Biosynthetic Process MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Release From Viral Latency Golgi Vesicle Docking Regulation Of Metabolic Process Toll-like Receptor 4 Signaling Pathway Biosynthetic Process Cellular Protein Complex Assembly RNA Splicing Cellular Metabolic Process Positive Regulation Of Cellular Metabolic Process Toll-like Receptor Signaling Pathway Mitochondrion Organization Negative Regulation Of Megakaryocyte Differentiation MRNA Processing Transcription From RNA Polymerase II Promoter Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction
Tagcloud ?		24h 300mum 513a 5p abp aminobiphenyl array arrays arylamine bioinformatic carcinogen comet damage deregulation eventually exo1 hepg2 lig1 mirna mirnas parallel pcna pcr qrt rad18 repair ung validated xrcc2	arsenic as1 cadmium capabilities cdkn2b chemical coding cycloheximide ethical flj33630 hipscs ideal indicators linc00152 linc0541471 lncrnas mir22hg mrnas peroxide pervasive pluripotent possess renewal responded rnas stresses surrogate toxicological v2
Tagcloud (Difference) ?		24h 300mum 513a 5p abp aminobiphenyl array arrays arylamine bioinformatic carcinogen comet damage deregulation eventually exo1 hepg2 lig1 mirna mirnas parallel pcna pcr qrt rad18 repair ung validated xrcc2	arsenic as1 cadmium capabilities cdkn2b chemical coding cycloheximide ethical flj33630 hipscs ideal indicators linc00152 linc0541471 lncrnas mir22hg mrnas peroxide pervasive pluripotent possess renewal responded rnas stresses surrogate toxicological v2
Tagcloud (Intersection) ?