FANCF and OLFM2

Number of citations: 0 (PubMedID 16169070)
Data Source: HPRD (two hybrid)

		FANCF	OLFM2
Name		FA complementation group F	olfactomedin 2
Structure			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytosol Fanconi Anaemia Nuclear Complex	Extracellular Region Extracellular Space Nucleus Nucleoplasm Cytoplasm Membrane AMPA Glutamate Receptor Complex Synapse
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	DNA Repair DNA Damage Response Interstrand Cross-link Repair	Signal Transduction Protein Secretion Positive Regulation Of Smooth Muscle Cell Differentiation Regulation Of Vascular Associated Smooth Muscle Cell Dedifferentiation
Pathways		Fanconi Anemia Pathway PKR-mediated signaling	None
Diseases		Fanconi anemia	None
GWAS		Parkinson's disease motor subtype (tremor dominant vs postural instability/gait difficulty) ( 33987465 )	Appendicular lean mass ( 33097823 ) Blood protein levels ( 30072576 ) Menarche (age at onset) ( 21102462 25231870 27182965 ) Sleep duration ( 30531941 )
Novel Interactors		1 novel interactors: ICAM1	1 novel interactors: ODAD3
Interacting Genes		13 interacting genes: CTBP1 FAAP100 FAAP20 FANCA FANCB FANCC FANCE FANCG FANCL HES1 MARK3 OLFM2 TCP11	15 interacting genes: BLOC1S6 EIF1 FANCF GNB5 KRTAP1-1 KRTAP1-3 KRTAP10-3 NBAS NBPF19 NOTCH2NLA PKM ROBO2 RPS6 SRSF5 ST13
Entrez ID		2188	93145
HPRD ID		04589	10127
Ensembl ID		ENSG00000183161	ENSG00000105088
Uniprot IDs		A3KME0 Q9NPI8	K7EIS8 K7EKW2 O95897
PDB IDs		2IQC 7KZP 7KZQ 7KZR 7KZS 7KZT 7KZV	Not available
GO Terms Enriched among Interactors		Fanconi Anaemia Nuclear Complex Interstrand Cross-link Repair DNA Repair Chromatin DNA Metabolic Process DNA Damage Response Cellular Response To Stress Nucleoplasm Nucleic Acid Metabolic Process Nucleobase-containing Compound Metabolic Process Transcription Corepressor Binding Ovarian Follicle Development Negative Regulation Of Pancreatic A Cell Differentiation N-box Binding Negative Regulation Of Cell Fate Determination Positive Regulation Of Mitotic Cell Cycle, Embryonic Trochlear Nerve Development Macromolecule Metabolic Process Response To Stress Negative Regulation Of Stomach Neuroendocrine Cell Differentiation Oculomotor Nerve Development Cajal-Retzius Cell Differentiation Negative Regulation Of Forebrain Neuron Differentiation Hindbrain Morphogenesis Renal Interstitial Fibroblast Development Nucleus Cardiac Neural Crest Cell Development Involved In Outflow Tract Morphogenesis Regulation Of Timing Of Neuron Differentiation Negative Regulation Of Inner Ear Auditory Receptor Cell Differentiation Ureteric Bud Morphogenesis Negative Regulation Of Lymphoid Progenitor Cell Differentiation Negative Regulation Of Inner Ear Receptor Cell Differentiation Negative Regulation Of Amacrine Cell Differentiation Negative Regulation Of Pro-B Cell Differentiation Regulation Of Mitotic Cell Cycle, Embryonic HLH Domain Binding Metanephric Nephron Tubule Morphogenesis Midbrain-hindbrain Boundary Morphogenesis Stomach Neuroendocrine Cell Differentiation Response To Aroclor 1254 Regulation Of Forebrain Neuron Differentiation Ascending Aorta Morphogenesis Lateral Inhibition Comma-shaped Body Morphogenesis T Cell Antigen Processing And Presentation Regulation Of Sperm Capacitation Notch Signaling Pathway	None