FANCG and FANCE

Number of citations of the paper that reports this interaction (PubMedID 12239156)
0

Data Source:
HPRD (two hybrid, in vitro)

		FANCG	FANCE
Description		FA complementation group G	FA complementation group E
Image
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm Mitochondrion Cytosol Nuclear Speck Fanconi Anaemia Nuclear Complex	Chromatin Nucleus Nucleoplasm Chromosome Centrosome Cytosol Fanconi Anaemia Nuclear Complex
	Molecular Function	Damaged DNA Binding Protein Binding	Protein Binding
	Biological Process	Ovarian Follicle Development DNA Repair DNA Damage Response Mitochondrion Organization Spermatid Development Response To Radiation Interstrand Cross-link Repair	Ovarian Follicle Development DNA Repair DNA Damage Response Gene Expression Interstrand Cross-link Repair Homeostasis Of Number Of Cells
Pathways		Fanconi Anemia Pathway PKR-mediated signaling	Fanconi Anemia Pathway PKR-mediated signaling
Drugs
Diseases		Fanconi anemia	Fanconi anemia
GWAS		Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Platelet count ( 32888494)	Height ( 28552196) Ovarian cancer ( 30557369) Pulmonary function (smoking interaction) ( 23284291)
Interacting Genes		44 interacting genes: BRCA2 BRCC3 CAPN1 CBY2 CDK1 COG6 CTBP1 CYP19A1 CYP2E1 DOK5 ERCC4 FANCA FANCC FANCE FANCF FTSJ3 GABPB1 GATA1 GOLGA2 HES1 HGS IHO1 IKZF3 KRT13 KRT19 LNX2 MEOX2 NECAB2 NLGN3 PSMB1 RINT1 RTN2 SAMD3 SSX2IP TADA2A TCEANC TFIP11 TLE5 TPRX1 UIMC1 USHBP1 XRCC3 ZBED1 ZBTB1	8 interacting genes: BRCA2 CHEK1 FANCA FANCC FANCD2 FANCF FANCG HES1
Entrez ID		2189	2178
HPRD ID		04262	02943
Ensembl ID		ENSG00000221829	ENSG00000112039
Uniprot IDs		O15287 Q53XM5	A0A8Q3WL50 A0A8Q3WMB8 Q9HB96
PDB IDs		7KZP 7KZQ 7KZR 7KZS 7KZT 7KZV	2ILR 7KZP 7KZQ 7KZR 7KZS 7KZT 7KZV
Enriched GO Terms of Interacting Partners?		DNA Metabolic Process DNA Damage Response DNA Repair Interstrand Cross-link Repair Fanconi Anaemia Nuclear Complex Mitotic G2 DNA Damage Checkpoint Signaling Telomere Maintenance Via Recombination Mitotic G2/M Transition Checkpoint Mitotic Recombination Nucleic Acid Metabolic Process Negative Regulation Of Cell Cycle G2/M Phase Transition Mitotic DNA Integrity Checkpoint Signaling Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle Mitotic DNA Damage Checkpoint Signaling Female Gonad Development Signal Transduction In Response To DNA Damage Nucleoplasm Nuclear Ubiquitin Ligase Complex Chromosome, Telomeric Region Golgi Disassembly Cellular Response To Stress Telomere Maintenance DNA Damage Checkpoint Signaling Regulation Of Glycoprotein Biosynthetic Process Regulation Of G2/M Transition Of Mitotic Cell Cycle BRCA1-A Complex Chromosome Organization Centrosome Cycle Regulation Of Cell Cycle G2/M Phase Transition Regulation Of Mitotic Cell Cycle Double-strand Break Repair Regulation Of Cell Cycle Positive Regulation Of Glutamate Receptor Signaling Pathway Telomere Organization Nucleotide-excision Repair Nucleobase-containing Compound Metabolic Process Gonad Development Regulation Of Lymphoid Progenitor Cell Differentiation Regulation Of Glutamate Receptor Signaling Pathway Regulation Of Primary Metabolic Process Meiosis I Cell Cycle Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle Phase Transition Nucleus Cellular Response To Radiation Organelle Organization Regulation Of Embryonic Development Microtubule Organizing Center Organization Chromatin Reproductive Structure Development	Interstrand Cross-link Repair Fanconi Anaemia Nuclear Complex DNA Repair DNA Metabolic Process DNA Damage Response Chromatin Cellular Response To Stress Nucleic Acid Metabolic Process Regulation Of CD40 Signaling Pathway Nucleoplasm Nucleobase-containing Compound Metabolic Process DNA Repair Complex Inner Cell Mass Cell Proliferation Positive Regulation Of Mitotic Cell Cycle Signal Transduction In Response To DNA Damage Regulation Of Mitotic Cell Cycle Response To Stress Neuronal Stem Cell Population Maintenance Female Gonad Development Regulation Of Regulatory T Cell Differentiation Male Meiotic Nuclear Division Nucleotide-excision Repair Response To Gamma Radiation BRCA2-MAGE-D1 Complex Nucleus Positive Regulation Of Cell Cycle Mitotic DNA Damage Checkpoint Signaling Negative Regulation Of Pancreatic A Cell Differentiation N-box Binding Negative Regulation Of Cell Fate Determination Positive Regulation Of Mitotic Cell Cycle, Embryonic Trochlear Nerve Development Mitotic DNA Integrity Checkpoint Signaling Meiotic Nuclear Division Regulation Of T Cell Activation Mitotic Recombination-dependent Replication Fork Processing Nuclear Division Response To Radiation Macromolecule Metabolic Process Regulation Of Cell Cycle Phase Transition Regulation Of Cell Cycle DNA Damage Checkpoint Signaling Negative Regulation Of Stomach Neuroendocrine Cell Differentiation Oculomotor Nerve Development Cajal-Retzius Cell Differentiation Negative Regulation Of Forebrain Neuron Differentiation Hindbrain Morphogenesis Renal Interstitial Fibroblast Development Histone H3T11 Kinase Activity Regulation Of Lymphocyte Activation
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