FANCG and FANCE

Number of citations of the paper that reports this interaction (PMID 11157805)
22

Data Source:
HPRD (two hybrid, in vitro)

		FANCG	FANCE
Gene Name		Fanconi anemia, complementation group G	Fanconi anemia, complementation group E
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Nucleolus Cytoplasm Mitochondrion Plasma Membrane Fanconi Anaemia Nuclear Complex	Nucleus Nucleoplasm Fanconi Anaemia Nuclear Complex
	Molecular Function	Damaged DNA Binding Protein Binding	Molecular_function
	Biological Process	Cell Cycle Checkpoint Ovarian Follicle Development DNA Repair Mitochondrion Organization Spermatid Development Response To Radiation	DNA Repair
Pathways		Fanconi Anemia pathway	Fanconi Anemia pathway
Drugs
Diseases
GWAS			Pulmonary function (interaction) ( 23284291)
Protein-Protein Interactions		22 interactors: BRCA2 BRCC3 CAPN1 CDK1 CYP19A1 CYP2E1 ERCC4 FANCA FANCC FANCE FANCF FTSJ3 GABPB1 HES1 KRT19 PSMB1 RTN2 SAMD3 UIMC1 USHBP1 XRCC3 ZBED1	8 interactors: BRCA2 CHEK1 FANCA FANCC FANCD2 FANCF FANCG HES1
Entrez ID		2189	2178
HPRD ID		04262	02943
Ensembl ID		ENSG00000221829	ENSG00000112039
Uniprot IDs		O15287 Q53XM5	Q9HB96
PDB IDs			2ILR
Enriched GO Terms of Interacting Partners?		Cellular Response To DNA Damage Stimulus DNA Repair DNA Metabolic Process Cellular Response To Stress Double-strand Break Repair Developmental Process Involved In Reproduction Heterocycle Metabolic Process Histone H2A K63-linked Deubiquitination Reproductive Structure Development Reproductive System Development Positive Regulation Of Mitotic Cell Cycle Single Organism Reproductive Process G2 DNA Damage Checkpoint Positive Regulation Of Cell Cycle Response To Stress Cellular Nitrogen Compound Metabolic Process Reproductive Process DNA Damage Checkpoint Nucleobase-containing Compound Metabolic Process Nitrogen Compound Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Mitotic Cell Cycle Cell Cycle Checkpoint Double-strand Break Repair Via Homologous Recombination Recombinational Repair Nucleotide-excision Repair Cell Cycle Cellular Response To Stimulus Protein K63-linked Deubiquitination Female Gonad Development Development Of Primary Female Sexual Characteristics Histone Deubiquitination Cellular Metabolic Process Reproduction Cell Cycle Process Response To Stimulus Response To Ionizing Radiation Positive Regulation Of DNA Metabolic Process Histone Modification Response To X-ray Meiotic Nuclear Division Muscle Cell Development Positive Regulation Of DNA Repair Response To Radiation Response To Reactive Oxygen Species Meiotic Cell Cycle Regulation Of Cell Cycle Gonad Development Nucleotide-excision Repair Involved In Interstrand Cross-link Repair Negative Regulation Of Stomach Neuroendocrine Cell Differentiation	DNA Repair Cellular Response To DNA Damage Stimulus DNA Metabolic Process Single Organism Reproductive Process Reproductive Process Developmental Process Involved In Reproduction Female Gonad Development Cellular Response To Stress Development Of Primary Female Sexual Characteristics Reproduction Reproductive Structure Development Reproductive System Development Gonad Development Development Of Primary Sexual Characteristics Gamete Generation Sex Differentiation Nucleobase-containing Compound Metabolic Process Sexual Reproduction Multicellular Organismal Reproductive Process Multicellular Organism Reproduction Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Response To Radiation Nitrogen Compound Metabolic Process Response To Stress Meiotic Nuclear Division Cell Cycle Meiotic Cell Cycle Cellular Response To Stimulus Germ Cell Development Response To Gamma Radiation Male Meiosis Response To Stimulus Cell Cycle Process Developmental Process Ovarian Follicle Development Cell Aging Regulation Of Mitotic Cell Cycle Response To Abiotic Stimulus Negative Regulation Of Stomach Neuroendocrine Cell Differentiation Negative Regulation Of Pancreatic A Cell Differentiation Pharyngeal Arch Artery Morphogenesis Lateral Inhibition Nucleotide-excision Repair Negative Regulation Of DNA Metabolic Process Ovulation Cycle Process Spermatogenesis Male Gamete Generation Meiosis I
Tagcloud ?		24h 300mum 513a 5p abp aminobiphenyl array arrays arylamine bioinformatic carcinogen comet damage deregulation eventually exo1 hepg2 lig1 mirna mirnas parallel pcna pcr qrt rad18 repair ung validated xrcc2	chek2 clk2 comprehensively escc esophageal fen1 gc genetics genotyped germline gtf2h3 han hel308 linxian mpg mre11a pole polq propensity rad54b rad54l resampling shanxi smug1 snps sum tdg validate warranted
Tagcloud (Difference) ?		24h 300mum 513a 5p abp aminobiphenyl array arrays arylamine bioinformatic carcinogen comet damage deregulation eventually exo1 hepg2 lig1 mirna mirnas parallel pcna pcr qrt rad18 repair ung validated xrcc2	chek2 clk2 comprehensively escc esophageal fen1 gc genetics genotyped germline gtf2h3 han hel308 linxian mpg mre11a pole polq propensity rad54b rad54l resampling shanxi smug1 snps sum tdg validate warranted
Tagcloud (Intersection) ?