FANCF

Name	FA complementation group F
Structure
Novel Interactors	1 novel interactors: ICAM1
Interactors	13 interactors: CTBP1 FAAP100 FAAP20 FANCA FANCB FANCC FANCE FANCG FANCL HES1 MARK3 OLFM2 TCP11
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytosol Fanconi Anaemia Nuclear Complex
	Molecular Function	Protein Binding
	Biological Process	DNA Repair DNA Damage Response Interstrand Cross-link Repair
Pathways	Fanconi Anemia Pathway PKR-mediated signaling
Diseases	Fanconi anemia
GWAS	Parkinson's disease motor subtype (tremor dominant vs postural instability/gait difficulty) ( 33987465 )
Entrez ID	2188
HPRD ID	04589
Ensembl ID	ENSG00000183161
Uniprot IDs	A3KME0 Q9NPI8
PDB IDs	2IQC 7KZP 7KZQ 7KZR 7KZS 7KZT 7KZV
GO Terms Enriched among Interactors ?	Fanconi Anaemia Nuclear Complex Interstrand Cross-link Repair DNA Repair Chromatin DNA Metabolic Process DNA Damage Response Cellular Response To Stress Nucleoplasm Nucleic Acid Metabolic Process Nucleobase-containing Compound Metabolic Process Transcription Corepressor Binding Ovarian Follicle Development Negative Regulation Of Pancreatic A Cell Differentiation N-box Binding Negative Regulation Of Cell Fate Determination Positive Regulation Of Mitotic Cell Cycle, Embryonic Trochlear Nerve Development Macromolecule Metabolic Process Response To Stress Negative Regulation Of Stomach Neuroendocrine Cell Differentiation Oculomotor Nerve Development Cajal-Retzius Cell Differentiation Negative Regulation Of Forebrain Neuron Differentiation Hindbrain Morphogenesis Renal Interstitial Fibroblast Development Nucleus Cardiac Neural Crest Cell Development Involved In Outflow Tract Morphogenesis Regulation Of Timing Of Neuron Differentiation Negative Regulation Of Inner Ear Auditory Receptor Cell Differentiation Ureteric Bud Morphogenesis Negative Regulation Of Lymphoid Progenitor Cell Differentiation Negative Regulation Of Inner Ear Receptor Cell Differentiation Negative Regulation Of Amacrine Cell Differentiation Negative Regulation Of Pro-B Cell Differentiation Regulation Of Mitotic Cell Cycle, Embryonic HLH Domain Binding Metanephric Nephron Tubule Morphogenesis Midbrain-hindbrain Boundary Morphogenesis Stomach Neuroendocrine Cell Differentiation Response To Aroclor 1254 Regulation Of Forebrain Neuron Differentiation Ascending Aorta Morphogenesis Lateral Inhibition Comma-shaped Body Morphogenesis T Cell Antigen Processing And Presentation Regulation Of Sperm Capacitation Notch Signaling Pathway