FANCF and FANCC

Number of citations of the paper that reports this interaction (PMID 11063725)
26

Data Source:
HPRD (in vivo)

		FANCF	FANCC
Gene Name		Fanconi anemia, complementation group F	Fanconi anemia, complementation group C
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Fanconi Anaemia Nuclear Complex	Nucleus Nucleoplasm Cytoplasm Cytosol Fanconi Anaemia Nuclear Complex
	Molecular Function	Molecular_function Ubiquitin-protein Transferase Activity Protein Binding	Protein Binding
	Biological Process	Ovarian Follicle Development DNA Repair Spermatogenesis Biological_process Protein Ubiquitination	Myeloid Cell Homeostasis DNA Repair Nucleotide-excision Repair Protein Complex Assembly Germ Cell Development Removal Of Superoxide Radicals
Pathways		Fanconi Anemia pathway	Fanconi Anemia pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: FANCA FANCC FANCE FANCG HES1 MARK3 OLFM2	27 interactors: ATP6 AZIN1 CAPN10 CDK1 DNAJB1 FANCA FANCD2 FANCE FANCF FANCG GSTP1 HSP90AA1 HSP90B1 HSPA1A HSPA4 HSPA8 IK KRT1 POR RPL18 RPS3A SPTA1 SPTAN1 STAT1 TCERG1 USP14 ZBTB32
Entrez ID		2188	2176
HPRD ID		04589	01967
Ensembl ID		ENSG00000183161	ENSG00000158169
Uniprot IDs		A3KME0 Q9NPI8	B4E3W2 Q00597
PDB IDs		2IQC
Enriched GO Terms of Interacting Partners?		DNA Repair Developmental Process Involved In Reproduction Cellular Response To DNA Damage Stimulus DNA Metabolic Process Single Organism Reproductive Process Reproductive Process Reproductive Structure Development Negative Regulation Of Stomach Neuroendocrine Cell Differentiation Negative Regulation Of Pancreatic A Cell Differentiation Pharyngeal Arch Artery Morphogenesis Lateral Inhibition Reproductive System Development Female Gonad Development Development Of Primary Female Sexual Characteristics Cellular Response To Stress Negative Regulation Of Forebrain Neuron Differentiation Negative Regulation Of Auditory Receptor Cell Differentiation Inhibition Of Neuroepithelial Cell Differentiation Negative Regulation Of Pro-B Cell Differentiation Negative Regulation Of Inner Ear Receptor Cell Differentiation Auditory Receptor Cell Fate Determination Trochlear Nerve Development Ascending Aorta Morphogenesis Positive Regulation Of Mitotic Cell Cycle, Embryonic Oculomotor Nerve Development Regulation Of Pro-B Cell Differentiation Regulation Of Auditory Receptor Cell Differentiation STAT Protein Import Into Nucleus Gonad Development Regulation Of Forebrain Neuron Differentiation Cardiac Neural Crest Cell Development Involved In Outflow Tract Morphogenesis Regulation Of Mitotic Cell Cycle, Embryonic Regulation Of Timing Of Neuron Differentiation Forebrain Radial Glial Cell Differentiation Comma-shaped Body Morphogenesis Development Of Primary Sexual Characteristics Common Bile Duct Development Metanephric Nephron Tubule Morphogenesis Midbrain-hindbrain Boundary Morphogenesis Renal Interstitial Fibroblast Development Germ Cell Development S-shaped Body Morphogenesis Protein Complex Assembly Reproduction Negative Regulation Of Hematopoietic Progenitor Cell Differentiation Neuron Fate Determination Auditory Receptor Cell Fate Commitment Negative Regulation Of Epidermal Cell Differentiation Positive Regulation Of Astrocyte Differentiation Radial Glial Cell Differentiation	Protein Refolding Response To Unfolded Protein Cellular Response To Stress Regulation Of Cellular Response To Heat Response To Stress Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Response To Heat DNA Repair Response To Stimulus Protein Import Into Mitochondrial Outer Membrane Response To Heat Protein Folding Response To Abiotic Stimulus Cellular Response To DNA Damage Stimulus Membrane Organization Cellular Metabolic Process Response To Organic Substance Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Inclusion Body Assembly Response To Temperature Stimulus Axon Guidance Response To Oxidative Stress Response To External Stimulus Chaperone-mediated Protein Complex Assembly DNA Metabolic Process Establishment Of Protein Localization To Membrane Nucleobase-containing Compound Metabolic Process Chaperone Mediated Protein Folding Requiring Cofactor Regulation Of Apoptotic Process Cellular Response To Organonitrogen Compound Regulation Of Inclusion Body Assembly Regulation Of Cell Death Protein Localization To Organelle Female Gonad Development Axonogenesis Development Of Primary Female Sexual Characteristics Cellular Macromolecule Catabolic Process Viral Process Cellular Response To Peptide Hormone Stimulus Axon Development Positive Regulation Of Immune System Process Negative Regulation Of Apoptotic Process Cellular Response To Peptide Nitric Oxide Metabolic Process Cell Morphogenesis Involved In Neuron Differentiation Regulation Of Immune System Process Negative Regulation Of Programmed Cell Death Metabolic Process
Tagcloud ?		bloom brca1 centrosome circumference connected coregulated coregulation divergent e2f e2f3 exploiting fanca fanconi fluctuations govern id jointly mesh microcephaly networks predisposition rb1 retinoblastoma silico subcellular subnetwork upregulation vital	1beta autoinhibitory bm characterizes creating cytokines fanca fanconi hypersensitive inactivated leukemic loop mapkapk mononuclear multipotent overproduced overproduction p38 phagocytes posttranscriptionally potently progenitor progenitors progressive reasoning tlr toll transcriptionally
Tagcloud (Difference) ?		bloom brca1 centrosome circumference connected coregulated coregulation divergent e2f e2f3 exploiting fluctuations govern id jointly mesh microcephaly networks predisposition rb1 retinoblastoma silico subcellular subnetwork upregulation vital	1beta autoinhibitory bm characterizes creating cytokines hypersensitive inactivated leukemic loop mapkapk mononuclear multipotent overproduced overproduction p38 phagocytes posttranscriptionally potently progenitor progenitors progressive reasoning tlr toll transcriptionally
Tagcloud (Intersection) ?		fanca fanconi