FANCG and KRT19

Number of citations of the paper that reports this interaction (PubMedID 16189514)
0

Data Source:
HPRD (two hybrid)

		FANCG	KRT19
Description		FA complementation group G	keratin 19
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GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm Mitochondrion Cytosol Nuclear Speck Fanconi Anaemia Nuclear Complex	Cytosol Cytoskeleton Intermediate Filament Plasma Membrane Dystrophin-associated Glycoprotein Complex Apicolateral Plasma Membrane Z Disc Sarcolemma Costamere Keratin Filament Extracellular Exosome Cell Periphery Terminal Web
	Molecular Function	Damaged DNA Binding Protein Binding	Structural Molecule Activity Structural Constituent Of Cytoskeleton Protein Binding Structural Constituent Of Muscle Structural Constituent Of Skin Epidermis Protein-containing Complex Binding
	Biological Process	Ovarian Follicle Development DNA Repair DNA Damage Response Mitochondrion Organization Spermatid Development Response To Radiation Interstrand Cross-link Repair	Morphogenesis Of An Epithelium Notch Signaling Pathway Epithelial Cell Differentiation Response To Estrogen Intermediate Filament Organization Sarcomere Organization Cell Differentiation Involved In Embryonic Placenta Development
Pathways		Fanconi Anemia Pathway PKR-mediated signaling	Keratinization Formation of the cornified envelope Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin Developmental Lineage of Pancreatic Ductal Cells Developmental Lineage of Mammary Gland Luminal Epithelial Cells Developmental Lineage of Mammary Gland Alveolar Cells
Drugs
Diseases		Fanconi anemia
GWAS		Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Platelet count ( 32888494)
Interacting Genes		44 interacting genes: BRCA2 BRCC3 CAPN1 CBY2 CDK1 COG6 CTBP1 CYP19A1 CYP2E1 DOK5 ERCC4 FANCA FANCC FANCE FANCF FTSJ3 GABPB1 GATA1 GOLGA2 HES1 HGS IHO1 IKZF3 KRT13 KRT19 LNX2 MEOX2 NECAB2 NLGN3 PSMB1 RINT1 RTN2 SAMD3 SSX2IP TADA2A TCEANC TFIP11 TLE5 TPRX1 UIMC1 USHBP1 XRCC3 ZBED1 ZBTB1	75 interacting genes: ABI2 AIRIM AMOT AMOTL2 ARL4A BEX2 CARD9 CCDC146 CCHCR1 CEP57L1 COPS4 DEPP1 DGCR6L DMD EIF4E2 EIF4ENIF1 ESR1 EXOC8 FAM107A FAM124B FANCG GFAP GLYCTK HAUS1 HGS IKZF3 KDM1A KIFC3 KRT1 KRT15 KRT4 KRT6A KRT6B KRT6C KRT71 KRT72 KRT73 KRT74 KRT76 KRT77 KRT78 KRT79 KRT80 KRT81 KRT82 KRT83 KRT85 KRT86 LENG1 LGALS14 NFKBID PCDHB12 PCM1 PKN1 PLEKHA5 PNN POLL POLR1C PPP1R18 PSMA1 RCOR3 SFI1 SGF29 SMARCB1 SMARCE1 SNAPIN SPG21 TBC1D7 TCHP TFPT TUBG1 UBE2I UCHL5 USHBP1 ZNF638
Entrez ID		2189	3880
HPRD ID		04262	01007
Ensembl ID		ENSG00000221829	ENSG00000171345
Uniprot IDs		O15287 Q53XM5	P08727
PDB IDs		7KZP 7KZQ 7KZR 7KZS 7KZT 7KZV	8XTN 8XTO 8Y3S 8ZUG
Enriched GO Terms of Interacting Partners?		DNA Metabolic Process DNA Damage Response DNA Repair Interstrand Cross-link Repair Fanconi Anaemia Nuclear Complex Mitotic G2 DNA Damage Checkpoint Signaling Telomere Maintenance Via Recombination Mitotic G2/M Transition Checkpoint Mitotic Recombination Nucleic Acid Metabolic Process Negative Regulation Of Cell Cycle G2/M Phase Transition Mitotic DNA Integrity Checkpoint Signaling Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle Mitotic DNA Damage Checkpoint Signaling Female Gonad Development Signal Transduction In Response To DNA Damage Nucleoplasm Nuclear Ubiquitin Ligase Complex Chromosome, Telomeric Region Golgi Disassembly Cellular Response To Stress Telomere Maintenance DNA Damage Checkpoint Signaling Regulation Of Glycoprotein Biosynthetic Process Regulation Of G2/M Transition Of Mitotic Cell Cycle BRCA1-A Complex Chromosome Organization Centrosome Cycle Regulation Of Cell Cycle G2/M Phase Transition Regulation Of Mitotic Cell Cycle Double-strand Break Repair Regulation Of Cell Cycle Positive Regulation Of Glutamate Receptor Signaling Pathway Telomere Organization Nucleotide-excision Repair Nucleobase-containing Compound Metabolic Process Gonad Development Regulation Of Lymphoid Progenitor Cell Differentiation Regulation Of Glutamate Receptor Signaling Pathway Regulation Of Primary Metabolic Process Meiosis I Cell Cycle Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle Phase Transition Nucleus Cellular Response To Radiation Organelle Organization Regulation Of Embryonic Development Microtubule Organizing Center Organization Chromatin Reproductive Structure Development	Intermediate Filament Organization Structural Constituent Of Skin Epidermis Intermediate Filament-based Process Intermediate Filament Cytoskeleton Organization Keratin Filament Keratinization Intermediate Filament Supramolecular Fiber Organization Cytoskeleton Organization Organelle Organization Cytosol Protein Binding Structural Constituent Of Cytoskeleton Establishment Of Cell Polarity Involved In Ameboidal Cell Migration Cytoskeleton Desmosome Epidermis Development Regulation Of Embryonic Development Regulation Of DNA Repair Cytoplasm
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