FANCF and FAAP20

Number of citations of the paper that reports this interaction (PubMedID 22343915)
42

Data Source:
BioGRID (affinity chromatography technology, pull down)

		FANCF	FAAP20
Description		FA complementation group F	FA core complex associated protein 20
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GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytosol Fanconi Anaemia Nuclear Complex	Chromatin Nucleus Nucleoplasm Chromosome Cytosol Nuclear Body Cell Junction Fanconi Anaemia Nuclear Complex
	Molecular Function	Protein Binding	Protein Binding Zinc Ion Binding Polyubiquitin Modification-dependent Protein Binding Ubiquitin Binding Metal Ion Binding K63-linked Polyubiquitin Modification-dependent Protein Binding Ubiquitin-modified Protein Reader Activity
	Biological Process	DNA Repair DNA Damage Response Interstrand Cross-link Repair	DNA Repair DNA Damage Response Translesion Synthesis Interstrand Cross-link Repair
Pathways		Fanconi Anemia Pathway PKR-mediated signaling	Fanconi Anemia Pathway PKR-mediated signaling
Drugs
Diseases		Fanconi anemia
GWAS		Parkinson's disease motor subtype (tremor dominant vs postural instability/gait difficulty) ( 33987465)	Sedentary behaviour duration ( 30531941) TPE interval (resting) ( 32386560)
Interacting Genes		13 interacting genes: CTBP1 FAAP100 FAAP20 FANCA FANCB FANCC FANCE FANCG FANCL HES1 MARK3 OLFM2 TCP11	28 interacting genes: ARNT2 BPIFA1 CRX CT55 CTDSP1 DDIT4L DUSP21 FANCF GOLGA6L9 INCA1 KRTAP6-2 KRTAP8-1 LCN2 LMO2 LRP2BP MEOX2 MOB2 NFKBID PFDN5 PIN1 PRDM5 REL REV1 SERTAD1 SERTAD3 TEX11 TRIB3 UBC
Entrez ID		2188	199990
HPRD ID		04589	08707
Ensembl ID		ENSG00000183161	ENSG00000162585
Uniprot IDs		A3KME0 Q9NPI8	F6S8H2 Q6NZ36 Q6ZRT9 Q7Z4P6
PDB IDs		2IQC 7KZP 7KZQ 7KZR 7KZS 7KZT 7KZV	2MUQ 2MUR 3WWQ
Enriched GO Terms of Interacting Partners?		Fanconi Anaemia Nuclear Complex Interstrand Cross-link Repair DNA Repair Chromatin DNA Metabolic Process DNA Damage Response Cellular Response To Stress Nucleoplasm Nucleic Acid Metabolic Process Nucleobase-containing Compound Metabolic Process Transcription Corepressor Binding Ovarian Follicle Development Negative Regulation Of Pancreatic A Cell Differentiation N-box Binding Negative Regulation Of Cell Fate Determination Positive Regulation Of Mitotic Cell Cycle, Embryonic Trochlear Nerve Development Macromolecule Metabolic Process Response To Stress Negative Regulation Of Stomach Neuroendocrine Cell Differentiation Oculomotor Nerve Development Cajal-Retzius Cell Differentiation Negative Regulation Of Forebrain Neuron Differentiation Hindbrain Morphogenesis Renal Interstitial Fibroblast Development Nucleus Cardiac Neural Crest Cell Development Involved In Outflow Tract Morphogenesis Regulation Of Timing Of Neuron Differentiation Negative Regulation Of Inner Ear Auditory Receptor Cell Differentiation Ureteric Bud Morphogenesis Negative Regulation Of Lymphoid Progenitor Cell Differentiation Negative Regulation Of Inner Ear Receptor Cell Differentiation Negative Regulation Of Amacrine Cell Differentiation Negative Regulation Of Pro-B Cell Differentiation Regulation Of Mitotic Cell Cycle, Embryonic HLH Domain Binding Metanephric Nephron Tubule Morphogenesis Midbrain-hindbrain Boundary Morphogenesis Stomach Neuroendocrine Cell Differentiation Response To Aroclor 1254 Regulation Of Forebrain Neuron Differentiation Ascending Aorta Morphogenesis Lateral Inhibition Comma-shaped Body Morphogenesis T Cell Antigen Processing And Presentation Regulation Of Sperm Capacitation Notch Signaling Pathway
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