FANCF and FAAP100

Number of citations: 42 (PubMedID 22343915)
Data Source: BioGRID (affinity chromatography technology, pull down)

		FANCF	FAAP100
Name		FA complementation group F	FA core complex associated protein 100
Structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytosol Fanconi Anaemia Nuclear Complex	Chromatin Nucleus Nucleoplasm Cytosol Fanconi Anaemia Nuclear Complex
	Molecular Function	Protein Binding	DNA Binding Protein Binding
	Biological Process	DNA Repair DNA Damage Response Interstrand Cross-link Repair	DNA Repair DNA Damage Response Interstrand Cross-link Repair
Pathways		Fanconi Anemia Pathway PKR-mediated signaling	Fanconi Anemia Pathway PKR-mediated signaling
Diseases		Fanconi anemia	None
GWAS		Parkinson's disease motor subtype (tremor dominant vs postural instability/gait difficulty) ( 33987465 )	No GWAS studies recorded
Interacting Genes		13 interacting genes: CTBP1 FAAP100 FAAP20 FANCA FANCB FANCC FANCE FANCG FANCL HES1 MARK3 OLFM2 TCP11	10 interacting genes: APP ATRIP CFTR FANCB FANCF FANCL HOXA1 LINC00839 MDFI PTGES3L-AARSD1
Entrez ID		2188	80233
HPRD ID		04589	07982
Ensembl ID		ENSG00000183161	ENSG00000185504
Uniprot IDs		A3KME0 Q9NPI8	A4ZI32 Q0VG06
PDB IDs		2IQC 7KZP 7KZQ 7KZR 7KZS 7KZT 7KZV	7KZP 7KZQ 7KZR 7KZS 7KZT 7KZV
GO Terms Enriched among Interactors		Fanconi Anaemia Nuclear Complex Interstrand Cross-link Repair DNA Repair Chromatin DNA Metabolic Process DNA Damage Response Cellular Response To Stress Nucleoplasm Nucleic Acid Metabolic Process Nucleobase-containing Compound Metabolic Process Transcription Corepressor Binding Ovarian Follicle Development Negative Regulation Of Pancreatic A Cell Differentiation N-box Binding Negative Regulation Of Cell Fate Determination Positive Regulation Of Mitotic Cell Cycle, Embryonic Trochlear Nerve Development Macromolecule Metabolic Process Response To Stress Negative Regulation Of Stomach Neuroendocrine Cell Differentiation Oculomotor Nerve Development Cajal-Retzius Cell Differentiation Negative Regulation Of Forebrain Neuron Differentiation Hindbrain Morphogenesis Renal Interstitial Fibroblast Development Nucleus Cardiac Neural Crest Cell Development Involved In Outflow Tract Morphogenesis Regulation Of Timing Of Neuron Differentiation Negative Regulation Of Inner Ear Auditory Receptor Cell Differentiation Ureteric Bud Morphogenesis Negative Regulation Of Lymphoid Progenitor Cell Differentiation Negative Regulation Of Inner Ear Receptor Cell Differentiation Negative Regulation Of Amacrine Cell Differentiation Negative Regulation Of Pro-B Cell Differentiation Regulation Of Mitotic Cell Cycle, Embryonic HLH Domain Binding Metanephric Nephron Tubule Morphogenesis Midbrain-hindbrain Boundary Morphogenesis Stomach Neuroendocrine Cell Differentiation Response To Aroclor 1254 Regulation Of Forebrain Neuron Differentiation Ascending Aorta Morphogenesis Lateral Inhibition Comma-shaped Body Morphogenesis T Cell Antigen Processing And Presentation Regulation Of Sperm Capacitation Notch Signaling Pathway	Fanconi Anaemia Nuclear Complex Interstrand Cross-link Repair Acetylcholine Receptor Activator Activity Protein-folding Chaperone Binding Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Visual Behavior Regulation Of Response To Calcium Ion Response To Stress Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To CAMP Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Response To CAMP Cellular Response To Stress Positive Regulation Of Anion Channel Activity Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Positive Regulation Of Monoatomic Anion Transport DNA Metabolic Process DNA Repair DNA Damage Response Semicircular Canal Formation Abducens Nerve Formation Optokinetic Behavior ATR-ATRIP Complex Negative Regulation Of Hepatic Stellate Cell Activation Nitric Oxide Catabolic Process Catalase Activity Fatty Acid Peroxidase Activity Nitric Oxide Dioxygenase Activity, Heme Protein As Donor Carbon Monoxide Binding Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Positive Regulation Of Enamel Mineralization Superoxide Dismutase Activity