FANCG and SAMD3

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		FANCG	SAMD3
Gene Name		Fanconi anemia, complementation group G	sterile alpha motif domain containing 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Nucleolus Cytoplasm Mitochondrion Plasma Membrane Fanconi Anaemia Nuclear Complex
	Molecular Function	Damaged DNA Binding Protein Binding	Protein Binding
	Biological Process	Cell Cycle Checkpoint Ovarian Follicle Development DNA Repair Mitochondrion Organization Spermatid Development Response To Radiation
Pathways		Fanconi Anemia pathway
Drugs
Diseases
GWAS			Height ( 18391951)
Protein-Protein Interactions		22 interactors: BRCA2 BRCC3 CAPN1 CDK1 CYP19A1 CYP2E1 ERCC4 FANCA FANCC FANCE FANCF FTSJ3 GABPB1 HES1 KRT19 PSMB1 RTN2 SAMD3 UIMC1 USHBP1 XRCC3 ZBED1	7 interactors: AKAP9 C6orf165 FANCG HSPD1 KDM1A LMO3 PRMT1
Entrez ID		2189	154075
HPRD ID		04262	11530
Ensembl ID		ENSG00000221829	ENSG00000164483
Uniprot IDs		O15287 Q53XM5	B4DY20 J3KQK4 Q8N6K7
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Response To DNA Damage Stimulus DNA Repair DNA Metabolic Process Cellular Response To Stress Double-strand Break Repair Developmental Process Involved In Reproduction Heterocycle Metabolic Process Histone H2A K63-linked Deubiquitination Reproductive Structure Development Reproductive System Development Positive Regulation Of Mitotic Cell Cycle Single Organism Reproductive Process G2 DNA Damage Checkpoint Positive Regulation Of Cell Cycle Response To Stress Cellular Nitrogen Compound Metabolic Process Reproductive Process DNA Damage Checkpoint Nucleobase-containing Compound Metabolic Process Nitrogen Compound Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Mitotic Cell Cycle Cell Cycle Checkpoint Double-strand Break Repair Via Homologous Recombination Recombinational Repair Nucleotide-excision Repair Cell Cycle Cellular Response To Stimulus Protein K63-linked Deubiquitination Female Gonad Development Development Of Primary Female Sexual Characteristics Histone Deubiquitination Cellular Metabolic Process Reproduction Cell Cycle Process Response To Stimulus Response To Ionizing Radiation Positive Regulation Of DNA Metabolic Process Histone Modification Response To X-ray Meiotic Nuclear Division Muscle Cell Development Positive Regulation Of DNA Repair Response To Radiation Response To Reactive Oxygen Species Meiotic Cell Cycle Regulation Of Cell Cycle Gonad Development Nucleotide-excision Repair Involved In Interstrand Cross-link Repair Negative Regulation Of Stomach Neuroendocrine Cell Differentiation	Regulation Of Megakaryocyte Differentiation Regulation Of Hematopoietic Progenitor Cell Differentiation Positive Regulation Of Glucocorticoid Receptor Signaling Pathway B Cell Cytokine Production Isotype Switching To IgG Isotypes Regulation Of Primitive Erythrocyte Differentiation Cell Development Positive Regulation Of T Cell Mediated Immune Response To Tumor Cell Regulation Of Myeloid Cell Differentiation System Development Negative Regulation Of Megakaryocyte Differentiation Gonad Development Development Of Primary Sexual Characteristics Multicellular Organismal Development Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Negative Regulation Of Histone H3-K4 Methylation Histone H3-K9 Demethylation Histone H3-K4 Demethylation Anatomical Structure Development Positive Regulation Of Immune Response To Tumor Cell Sex Differentiation Negative Regulation Of Hematopoietic Progenitor Cell Differentiation Positive Regulation Of Peroxisome Proliferator Activated Receptor Signaling Pathway Positive Regulation Of Megakaryocyte Differentiation Positive Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Immune System Process Positive Regulation Of Hormone Biosynthetic Process Positive Regulation Of Potassium Ion Transmembrane Transporter Activity Positive Regulation Of Macrophage Activation Peptidyl-arginine N-methylation Negative Regulation Of Histone H3-K9 Methylation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Developmental Process Histone H4-R3 Methylation Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Chaperone-mediated Protein Complex Assembly Cytokine Production Involved In Immune Response Organelle Organization Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of Peroxisome Proliferator Activated Receptor Signaling Pathway Histone Modification Granulocyte Differentiation Negative Regulation Of Intracellular Signal Transduction Positive Regulation Of Potassium Ion Transmembrane Transport Histone Arginine Methylation Positive Regulation Of Interferon-alpha Production Peptidyl-arginine Methylation Negative Regulation Of Histone Methylation Regulation Of Cell Differentiation
Tagcloud ?		24h 300mum 513a 5p abp aminobiphenyl array arrays arylamine bioinformatic carcinogen comet damage deregulation eventually exo1 hepg2 lig1 mirna mirnas parallel pcna pcr qrt rad18 repair ung validated xrcc2	adjacent androgen androgens antagonistic antagonistically ar btg1 cdca7l cdk6 chip confirming depends find htgp immunoprecipitation mapped position prostate proved publicly ra rar rare responsive restricted retinoic seq tgm4 transactivation
Tagcloud (Difference) ?		24h 300mum 513a 5p abp aminobiphenyl array arrays arylamine bioinformatic carcinogen comet damage deregulation eventually exo1 hepg2 lig1 mirna mirnas parallel pcna pcr qrt rad18 repair ung validated xrcc2	adjacent androgen androgens antagonistic antagonistically ar btg1 cdca7l cdk6 chip confirming depends find htgp immunoprecipitation mapped position prostate proved publicly ra rar rare responsive restricted retinoic seq tgm4 transactivation
Tagcloud (Intersection) ?