FANCF and FANCE

Number of citations of the paper that reports this interaction (PubMedID 27986371)
0

Data Source:
BioGRID (pull down)

		FANCF	FANCE
Description		FA complementation group F	FA complementation group E
Image
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytosol Fanconi Anaemia Nuclear Complex	Chromatin Nucleus Nucleoplasm Chromosome Centrosome Cytosol Fanconi Anaemia Nuclear Complex
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	DNA Repair DNA Damage Response Interstrand Cross-link Repair	Ovarian Follicle Development DNA Repair DNA Damage Response Gene Expression Interstrand Cross-link Repair Homeostasis Of Number Of Cells
Pathways		Fanconi Anemia Pathway PKR-mediated signaling	Fanconi Anemia Pathway PKR-mediated signaling
Drugs
Diseases		Fanconi anemia	Fanconi anemia
GWAS		Parkinson's disease motor subtype (tremor dominant vs postural instability/gait difficulty) ( 33987465)	Height ( 28552196) Ovarian cancer ( 30557369) Pulmonary function (smoking interaction) ( 23284291)
Interacting Genes		13 interacting genes: CTBP1 FAAP100 FAAP20 FANCA FANCB FANCC FANCE FANCG FANCL HES1 MARK3 OLFM2 TCP11	8 interacting genes: BRCA2 CHEK1 FANCA FANCC FANCD2 FANCF FANCG HES1
Entrez ID		2188	2178
HPRD ID		04589	02943
Ensembl ID		ENSG00000183161	ENSG00000112039
Uniprot IDs		A3KME0 Q9NPI8	A0A8Q3WL50 A0A8Q3WMB8 Q9HB96
PDB IDs		2IQC 7KZP 7KZQ 7KZR 7KZS 7KZT 7KZV	2ILR 7KZP 7KZQ 7KZR 7KZS 7KZT 7KZV
Enriched GO Terms of Interacting Partners?		Fanconi Anaemia Nuclear Complex Interstrand Cross-link Repair DNA Repair Chromatin DNA Metabolic Process DNA Damage Response Cellular Response To Stress Nucleoplasm Nucleic Acid Metabolic Process Nucleobase-containing Compound Metabolic Process Transcription Corepressor Binding Ovarian Follicle Development Negative Regulation Of Pancreatic A Cell Differentiation N-box Binding Negative Regulation Of Cell Fate Determination Positive Regulation Of Mitotic Cell Cycle, Embryonic Trochlear Nerve Development Macromolecule Metabolic Process Response To Stress Negative Regulation Of Stomach Neuroendocrine Cell Differentiation Oculomotor Nerve Development Cajal-Retzius Cell Differentiation Negative Regulation Of Forebrain Neuron Differentiation Hindbrain Morphogenesis Renal Interstitial Fibroblast Development Nucleus Cardiac Neural Crest Cell Development Involved In Outflow Tract Morphogenesis Regulation Of Timing Of Neuron Differentiation Negative Regulation Of Inner Ear Auditory Receptor Cell Differentiation Ureteric Bud Morphogenesis Negative Regulation Of Lymphoid Progenitor Cell Differentiation Negative Regulation Of Inner Ear Receptor Cell Differentiation Negative Regulation Of Amacrine Cell Differentiation Negative Regulation Of Pro-B Cell Differentiation Regulation Of Mitotic Cell Cycle, Embryonic HLH Domain Binding Metanephric Nephron Tubule Morphogenesis Midbrain-hindbrain Boundary Morphogenesis Stomach Neuroendocrine Cell Differentiation Response To Aroclor 1254 Regulation Of Forebrain Neuron Differentiation Ascending Aorta Morphogenesis Lateral Inhibition Comma-shaped Body Morphogenesis T Cell Antigen Processing And Presentation Regulation Of Sperm Capacitation Notch Signaling Pathway	Interstrand Cross-link Repair Fanconi Anaemia Nuclear Complex DNA Repair DNA Metabolic Process DNA Damage Response Chromatin Cellular Response To Stress Nucleic Acid Metabolic Process Regulation Of CD40 Signaling Pathway Nucleoplasm Nucleobase-containing Compound Metabolic Process DNA Repair Complex Inner Cell Mass Cell Proliferation Positive Regulation Of Mitotic Cell Cycle Signal Transduction In Response To DNA Damage Regulation Of Mitotic Cell Cycle Response To Stress Neuronal Stem Cell Population Maintenance Female Gonad Development Regulation Of Regulatory T Cell Differentiation Male Meiotic Nuclear Division Nucleotide-excision Repair Response To Gamma Radiation BRCA2-MAGE-D1 Complex Nucleus Positive Regulation Of Cell Cycle Mitotic DNA Damage Checkpoint Signaling Negative Regulation Of Pancreatic A Cell Differentiation N-box Binding Negative Regulation Of Cell Fate Determination Positive Regulation Of Mitotic Cell Cycle, Embryonic Trochlear Nerve Development Mitotic DNA Integrity Checkpoint Signaling Meiotic Nuclear Division Regulation Of T Cell Activation Mitotic Recombination-dependent Replication Fork Processing Nuclear Division Response To Radiation Macromolecule Metabolic Process Regulation Of Cell Cycle Phase Transition Regulation Of Cell Cycle DNA Damage Checkpoint Signaling Negative Regulation Of Stomach Neuroendocrine Cell Differentiation Oculomotor Nerve Development Cajal-Retzius Cell Differentiation Negative Regulation Of Forebrain Neuron Differentiation Hindbrain Morphogenesis Renal Interstitial Fibroblast Development Histone H3T11 Kinase Activity Regulation Of Lymphocyte Activation
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