FABP4 and CHD3

Number of citations of the paper that reports this interaction (PubMedID 21900206)
0

Data Source:
BioGRID (two hybrid)

		FABP4	CHD3
Description		fatty acid binding protein 4	chromodomain helicase DNA binding protein 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Lipid Droplet Cytosol Extracellular Exosome	Chromatin Nucleus Nucleoplasm Nucleolus Cytoplasm Centrosome Cytoskeleton NuRD Complex PML Body Centriolar Satellite
	Molecular Function	Long-chain Fatty Acid Transmembrane Transporter Activity Fatty Acid Binding Lipid Binding Long-chain Fatty Acid Binding Hormone Receptor Binding	Nucleotide Binding Transcription Cis-regulatory Region Binding DNA Binding Chromatin Binding RNA Binding Helicase Activity Protein Binding ATP Binding Zinc Ion Binding Hydrolase Activity ATP Hydrolysis Activity Histone Binding Metal Ion Binding ATP-dependent Chromatin Remodeler Activity
	Biological Process	Response To Bacterium Fatty Acid Transport Long-chain Fatty Acid Transport Cholesterol Homeostasis Negative Regulation Of DNA-templated Transcription Positive Regulation Of Inflammatory Response White Fat Cell Differentiation Brown Fat Cell Differentiation Cellular Response To Lithium Ion Cellular Response To Tumor Necrosis Factor Positive Regulation Of Cold-induced Thermogenesis	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Chromatin Remodeling Regulation Of DNA-templated Transcription Spindle Organization Centrosome Cycle Regulation Of Cell Fate Specification Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Regulation Of Stem Cell Differentiation
Pathways		Triglyceride catabolism Triglyceride catabolism Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis	HDACs deacetylate histones ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression SUMOylation of chromatin organization proteins Regulation of TP53 Activity through Acetylation RNA Polymerase I Transcription Initiation Regulation of PTEN gene transcription Regulation of PTEN gene transcription Potential therapeutics for SARS Regulation of endogenous retroelements by KRAB-ZFP proteins Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs)
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Metabolite levels ( 23823483) Ovarian cancer ( 23535730) Visceral fat ( 22589738)	Ischemic stroke ( 26089329) Macular thickness ( 30535121) Prostate cancer ( 29892016) Refractive error ( 32231278) Stroke ( 26089329)
Interacting Genes		9 interacting genes: ACP1 ACTB CHD3 INSR LIPE PRKCI TNFAIP3 VIM ZBED1	101 interacting genes: ACTR1B ADH5 AIMP2 ATP5IF1 BARD1 BCL6 BHLHE40 C4orf17 CASP6 CASP8 CBX4 CPE CRCT1 CREB1 CREBBP CSTF2 CTBP1 CTTN ENTR1 ETV5 FABP4 FBP2 FUBP1 GADD45A GIT1 GPS2 GSK3B HABP4 HSD17B10 HSPH1 HTT IK IKZF1 IKZF3 IMMT IVNS1ABP KIF15 KPNA2 KPNB1 LRIF1 LUC7L2 MAFG MAN2A2 MX1 MYB NEFL NR1H2 NR4A1 PAICS PCMT1 PIAS1 PIAS4 PLK4 PRG2 PRPF40A PSME1 PTN PTPRS PUF60 RAD51 RETREG2 RGS2 RIF1 RNF10 RPL29 SAFB SAT1 SATB1 SERBP1 SERF2 SETX SGSM2 SIRT6 SKIL SLC27A6 SPOP SRRT STIP1 SUMO1 SUMO2 TAL1 TCERG1 THOC7 TNFRSF14 TNNT1 TP53 TP73 TRIM28 TRIM54 TSC22D1 TSPAN6 TTR TXNDC9 UBA3 UBC UBE2I UROD VIM XRCC4 YAE1 ZHX1
Entrez ID		2167	1107
HPRD ID		02698	09071
Ensembl ID		ENSG00000170323	ENSG00000170004
Uniprot IDs		E7DVW4 P15090	A0A8V8TR54 B3KWV4 Q12873 Q2TAZ1
PDB IDs		1TOU 1TOW 2HNX 2NNQ 3FR2 3FR4 3FR5 3P6C 3P6D 3P6E 3P6F 3P6G 3P6H 3Q6L 3RZY 4NNS 4NNT 5D45 5D47 5D48 5D4A 5EDB 5EDC 5HZ6 5HZ8 5Y0F 5Y0G 5Y0X 5Y12 5Y13 6AYL 6LJS 6LJT 6LJU 6LJV 6LJW 6LJX 7FVU 7FVV 7FVW 7FVX 7FVY 7FVZ 7FW0 7FW1 7FW2 7FW3 7FW4 7FW5 7FW6 7FW7 7FW8 7FW9 7FWA 7FWB 7FWC 7FWD 7FWE 7FWF 7FWG 7FWH 7FWJ 7FWK 7FWL 7FWM 7FWN 7FWO 7FWP 7FWQ 7FWR 7FWS 7FWU 7FWV 7FWW 7FWX 7FWY 7FWZ 7FX0 7FX1 7FX2 7FX3 7FX4 7FX5 7FX6 7FX7 7FX8 7FX9 7FXA 7FXB 7FXC 7FXE 7FXF 7FXG 7FXH 7FXI 7FXJ 7FXK 7FXL 7FXM 7FXN 7FXP 7FXQ 7FXR 7FXS 7FXT 7FXU 7FXV 7FXW 7FXX 7FXY 7FXZ 7FY2 7FY3 7FY4 7FY5 7FY6 7FY7 7FY9 7FYB 7FYC 7FYE 7FYF 7FYG 7FYH 7FYI 7FYJ 7FYK 7FYL 7FYM 7FYO 7FYP 7FYQ 7FYR 7FYS 7FYT 7FYU 7FYV 7FYX 7FYY 7FYZ 7FZ0 7FZ1 7FZ2 7FZ3 7FZ4 7FZ5 7FZ6 7FZ7 7FZ8 7FZ9 7FZA 7FZB 7FZC 7FZD 7FZE 7FZF 7FZH 7FZI 7FZJ 7FZK 7FZL 7FZM 7FZN 7FZO 7FZP 7FZR 7FZS 7FZT 7FZU 7FZV 7FZW 7FZX 7FZY 7FZZ 7G02 7G03 7G05 7G06 7G07 7G08 7G09 7G0A 7G0C 7G0F 7G0G 7G0H 7G0I 7G0J 7G0K 7G0L 7G0M 7G0N 7G0O 7G0P 7G0Q 7G0R 7G0S 7G0T 7G0U 7G0V 7G0X 7G0Y 7G0Z 7G10 7G11 7G12 7G13 7G14 7G15 7G16 7G17 7G18 7G19 7G1A 7G1B 7G1C 7G1D 7G1E 7G1F 7G1G 7G1H 7G1I 7G1J 7G1K 7G1L 7G1M 7G1N 7G1O 7G1P 7G1R 7G1S 7G1T 7G1U 7G1V 7G1W 7G1Y 7G1Z 7G20 7G21 7WC3 8S1K 8WDX 8WE3
Enriched GO Terms of Interacting Partners?		Cytoskeleton Organization Cellular Response To Oxygen-containing Compound Response To Muramyl Dipeptide Extracellular Exosome Tight Junction Positive Regulation Of D-glucose Import Brush Border Positive Regulation Of Norepinephrine Uptake Cellular Response To Cytochalasin B Positive Regulation Of D-glucose Transmembrane Transport Regulation Of D-glucose Import Regulation Of Endothelial Cell Apoptotic Process Cell Leading Edge Tolerance Induction To Lipopolysaccharide Negative Regulation Of Toll-like Receptor 5 Signaling Pathway Negative Regulation Of Nucleotide-binding Oligomerization Domain Containing 1 Signaling Pathway Protein Autosumoylation Hydrolase Activity Protein Modification Process Protein Phosphorylation Caveola Regulation Of D-glucose Transmembrane Transport Positive Regulation Of Cell Population Proliferation Phosphorylation Axon Regulation Of Norepinephrine Uptake Identical Protein Binding Diacylglycerol Lipase Activity Negative Regulation Of CD40 Signaling Pathway Schaffer Collateral - CA1 Synapse Structural Constituent Of Cytoskeleton Cellular Response To Insulin Stimulus Transporter Regulator Activity PML Body PTB Domain Binding Insulin Receptor Activity All-trans-retinyl-palmitate Hydrolase, All-trans-retinol Forming Activity Negative Regulation Of Toll-like Receptor 3 Signaling Pathway Negative Regulation Of Osteoclast Proliferation Positive Regulation Of Macromolecule Metabolic Process Regulation Of Protein Localization To Plasma Membrane Regulation Of Transepithelial Transport Nuclear Matrix Insulin Receptor Complex Sterol Ester Esterase Activity Golgi Vesicle Budding Diacylglycerol-dependent, Calcium-independent Serine/threonine Kinase Activity Negative Regulation Of Chronic Inflammatory Response Negative Regulation Of Nucleotide-binding Oligomerization Domain Containing 2 Signaling Pathway B-1 B Cell Homeostasis	Nucleoplasm Nucleus Negative Regulation Of Transcription By RNA Polymerase II Identical Protein Binding Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of Biosynthetic Process SUMO Transferase Activity Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Metabolic Process PML Body Protein Sumoylation Regulation Of DNA-templated Transcription Negative Regulation Of Metabolic Process Regulation Of RNA Biosynthetic Process Cytoplasm Regulation Of Macromolecule Metabolic Process Regulation Of Primary Metabolic Process Positive Regulation Of Apoptotic Process Regulation Of Metabolic Process Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Programmed Cell Death RNA Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding Regulation Of Gene Expression Ubiquitin Protein Ligase Binding Regulation Of Cell Development Presynaptic Cytosol Postsynaptic Cytosol Enzyme Binding Positive Regulation Of Metabolic Process Nucleic Acid Metabolic Process Nuclear Speck Regulation Of Neurogenesis Macromolecule Metabolic Process DNA Repair Positive Regulation Of Macromolecule Metabolic Process Regulation Of Gliogenesis Protein-containing Complex Regulation Of Proteolysis Positive Regulation Of Neuron Apoptotic Process Regulation Of Cellular Response To Stress Regulation Of Cell Differentiation Transcription Corepressor Activity Promoter-specific Chromatin Binding
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