FABP4 and PRKCI

Number of citations of the paper that reports this interaction (PubMedID 21900206)
0

Data Source:
BioGRID (two hybrid)

		FABP4	PRKCI
Description		fatty acid binding protein 4	protein kinase C iota
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Lipid Droplet Cytosol Extracellular Exosome	Golgi Membrane Nucleus Nucleoplasm Cytoplasm Endosome Cytosol Plasma Membrane Brush Border Bicellular Tight Junction Cilium Microtubule Cytoskeleton Membrane Apical Plasma Membrane Cell Leading Edge Schmidt-Lanterman Incisure Intercellular Bridge Apical Part Of Cell Extracellular Exosome Tight Junction Schaffer Collateral - CA1 Synapse Glutamatergic Synapse PAR Polarity Complex
	Molecular Function	Long-chain Fatty Acid Transmembrane Transporter Activity Fatty Acid Binding Lipid Binding Long-chain Fatty Acid Binding Hormone Receptor Binding	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Diacylglycerol-dependent Serine/threonine Kinase Activity Diacylglycerol-dependent, Calcium-independent Serine/threonine Kinase Activity Protein Binding ATP Binding Phospholipid Binding Zinc Ion Binding Kinase Activity Transferase Activity Metal Ion Binding Protein Serine Kinase Activity
	Biological Process	Response To Bacterium Fatty Acid Transport Long-chain Fatty Acid Transport Cholesterol Homeostasis Negative Regulation Of DNA-templated Transcription Positive Regulation Of Inflammatory Response White Fat Cell Differentiation Brown Fat Cell Differentiation Cellular Response To Lithium Ion Cellular Response To Tumor Necrosis Factor Positive Regulation Of Cold-induced Thermogenesis	Protein Phosphorylation Protein Targeting To Membrane Cytoskeleton Organization Actin Filament Organization Positive Regulation Of Neuron Projection Development Vesicle-mediated Transport Cell Migration Establishment Of Cell Polarity Cellular Response To Insulin Stimulus Negative Regulation Of Glial Cell Apoptotic Process Establishment Of Apical/basal Cell Polarity Intracellular Signal Transduction Eye Photoreceptor Cell Development Negative Regulation Of Apoptotic Process Response To Peptide Hormone Negative Regulation Of Neuron Apoptotic Process Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Cell-cell Junction Organization Positive Regulation Of Notch Signaling Pathway Positive Regulation Of D-glucose Import Secretion Golgi Vesicle Budding Positive Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of Glial Cell Proliferation Membrane Organization Cellular Response To Chemical Stress Response To Interleukin-1 Protein Localization To Plasma Membrane Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels Positive Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Endothelial Cell Apoptotic Process
Pathways		Triglyceride catabolism Triglyceride catabolism Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis	Pre-NOTCH Transcription and Translation p75NTR recruits signalling complexes Tight junction interactions KEAP1-NFE2L2 pathway
Drugs			Tamoxifen Staurosporine Bisindolylmaleimide I Dequalinium Benzoyl peroxide Fostamatinib
Diseases
GWAS		Blood protein levels ( 30072576) Metabolite levels ( 23823483) Ovarian cancer ( 23535730) Visceral fat ( 22589738)	Aspartate aminotransferase levels ( 33547301) Microalbuminuria ( 31511532) Prostate cancer ( 25939597) Urinary albumin excretion ( 30220432) Urinary albumin-to-creatinine ratio ( 31511532 31630189)
Interacting Genes		9 interacting genes: ACP1 ACTB CHD3 INSR LIPE PRKCI TNFAIP3 VIM ZBED1	51 interacting genes: ADAP1 ANXA1 APP BAD CASK CASP8 CCNT1 CDC42 CDK7 CHUK CTBP1 FABP4 FCGR3A FRS2 FRS3 GAPDH HRAS IKBKG IL1RAP IRAK1 MAP2K1 MAP2K5 MAPT MARK4 MBP MEOX2 NACC1 NFKBIA PARD3 PARD6A PARD6B PARD6G PCM1 PDPK1 PNMA1 RAB2A RAB4A RAC1 RBM14 RHOQ SMG1 SMURF1 SQSTM1 SRC TSC22D1 TTR UBC USP20 VHL YWHAH YWHAZ
Entrez ID		2167	5584
HPRD ID		02698	02105
Ensembl ID		ENSG00000170323	ENSG00000163558
Uniprot IDs		E7DVW4 P15090	P41743
PDB IDs		1TOU 1TOW 2HNX 2NNQ 3FR2 3FR4 3FR5 3P6C 3P6D 3P6E 3P6F 3P6G 3P6H 3Q6L 3RZY 4NNS 4NNT 5D45 5D47 5D48 5D4A 5EDB 5EDC 5HZ6 5HZ8 5Y0F 5Y0G 5Y0X 5Y12 5Y13 6AYL 6LJS 6LJT 6LJU 6LJV 6LJW 6LJX 7FVU 7FVV 7FVW 7FVX 7FVY 7FVZ 7FW0 7FW1 7FW2 7FW3 7FW4 7FW5 7FW6 7FW7 7FW8 7FW9 7FWA 7FWB 7FWC 7FWD 7FWE 7FWF 7FWG 7FWH 7FWJ 7FWK 7FWL 7FWM 7FWN 7FWO 7FWP 7FWQ 7FWR 7FWS 7FWU 7FWV 7FWW 7FWX 7FWY 7FWZ 7FX0 7FX1 7FX2 7FX3 7FX4 7FX5 7FX6 7FX7 7FX8 7FX9 7FXA 7FXB 7FXC 7FXE 7FXF 7FXG 7FXH 7FXI 7FXJ 7FXK 7FXL 7FXM 7FXN 7FXP 7FXQ 7FXR 7FXS 7FXT 7FXU 7FXV 7FXW 7FXX 7FXY 7FXZ 7FY2 7FY3 7FY4 7FY5 7FY6 7FY7 7FY9 7FYB 7FYC 7FYE 7FYF 7FYG 7FYH 7FYI 7FYJ 7FYK 7FYL 7FYM 7FYO 7FYP 7FYQ 7FYR 7FYS 7FYT 7FYU 7FYV 7FYX 7FYY 7FYZ 7FZ0 7FZ1 7FZ2 7FZ3 7FZ4 7FZ5 7FZ6 7FZ7 7FZ8 7FZ9 7FZA 7FZB 7FZC 7FZD 7FZE 7FZF 7FZH 7FZI 7FZJ 7FZK 7FZL 7FZM 7FZN 7FZO 7FZP 7FZR 7FZS 7FZT 7FZU 7FZV 7FZW 7FZX 7FZY 7FZZ 7G02 7G03 7G05 7G06 7G07 7G08 7G09 7G0A 7G0C 7G0F 7G0G 7G0H 7G0I 7G0J 7G0K 7G0L 7G0M 7G0N 7G0O 7G0P 7G0Q 7G0R 7G0S 7G0T 7G0U 7G0V 7G0X 7G0Y 7G0Z 7G10 7G11 7G12 7G13 7G14 7G15 7G16 7G17 7G18 7G19 7G1A 7G1B 7G1C 7G1D 7G1E 7G1F 7G1G 7G1H 7G1I 7G1J 7G1K 7G1L 7G1M 7G1N 7G1O 7G1P 7G1R 7G1S 7G1T 7G1U 7G1V 7G1W 7G1Y 7G1Z 7G20 7G21 7WC3 8S1K 8WDX 8WE3	1VD2 1WMH 1ZRZ 3A8W 3A8X 3ZH8 5LI1 5LI9 5LIH 6ILZ 8R3X 8R3Y
Enriched GO Terms of Interacting Partners?		Cytoskeleton Organization Cellular Response To Oxygen-containing Compound Response To Muramyl Dipeptide Extracellular Exosome Tight Junction Positive Regulation Of D-glucose Import Brush Border Positive Regulation Of Norepinephrine Uptake Cellular Response To Cytochalasin B Positive Regulation Of D-glucose Transmembrane Transport Regulation Of D-glucose Import Regulation Of Endothelial Cell Apoptotic Process Cell Leading Edge Tolerance Induction To Lipopolysaccharide Negative Regulation Of Toll-like Receptor 5 Signaling Pathway Negative Regulation Of Nucleotide-binding Oligomerization Domain Containing 1 Signaling Pathway Protein Autosumoylation Hydrolase Activity Protein Modification Process Protein Phosphorylation Caveola Regulation Of D-glucose Transmembrane Transport Positive Regulation Of Cell Population Proliferation Phosphorylation Axon Regulation Of Norepinephrine Uptake Identical Protein Binding Diacylglycerol Lipase Activity Negative Regulation Of CD40 Signaling Pathway Schaffer Collateral - CA1 Synapse Structural Constituent Of Cytoskeleton Cellular Response To Insulin Stimulus Transporter Regulator Activity PML Body PTB Domain Binding Insulin Receptor Activity All-trans-retinyl-palmitate Hydrolase, All-trans-retinol Forming Activity Negative Regulation Of Toll-like Receptor 3 Signaling Pathway Negative Regulation Of Osteoclast Proliferation Positive Regulation Of Macromolecule Metabolic Process Regulation Of Protein Localization To Plasma Membrane Regulation Of Transepithelial Transport Nuclear Matrix Insulin Receptor Complex Sterol Ester Esterase Activity Golgi Vesicle Budding Diacylglycerol-dependent, Calcium-independent Serine/threonine Kinase Activity Negative Regulation Of Chronic Inflammatory Response Negative Regulation Of Nucleotide-binding Oligomerization Domain Containing 2 Signaling Pathway B-1 B Cell Homeostasis	Cytoplasm Cytosol Intracellular Signaling Cassette Positive Regulation Of Metabolic Process Cell Surface Receptor Signaling Pathway Regulation Of Cellular Localization Intracellular Signal Transduction Immune System Process PAR Polarity Complex Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Signal Transduction Regulation Of Protein Localization Positive Regulation Of Biosynthetic Process Regulation Of Multicellular Organismal Process Regulation Of Intracellular Signal Transduction Positive Regulation Of Immune System Process Regulation Of Macromolecule Metabolic Process Regulation Of Canonical NF-kappaB Signal Transduction Response To Stress Regulation Of Gene Expression Positive Regulation Of Protein Localization Regulation Of Immune Response Plasma Membrane Regulation Of Metabolic Process Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cell Projection Organization Regulation Of Programmed Cell Death Immune Response-regulating Cell Surface Receptor Signaling Pathway Positive Regulation Of Multicellular Organismal Process Regulation Of Organelle Organization Negative Regulation Of Programmed Cell Death Protein Serine/threonine Kinase Activity Regulation Of Signaling Regulation Of Cell Communication Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Regulation Of Immune System Process Regulation Of Plasma Membrane Bounded Cell Projection Organization Regulation Of Apoptotic Process Establishment Or Maintenance Of Cell Polarity Establishment Or Maintenance Of Apical/basal Cell Polarity Regulation Of Cell Projection Organization Negative Regulation Of Canonical NF-kappaB Signal Transduction Regulation Of Cytokine Production Regulation Of Primary Metabolic Process Regulation Of Innate Immune Response Immune Response-activating Cell Surface Receptor Signaling Pathway Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Cell Population Proliferation Positive Regulation Of Intracellular Signal Transduction
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?