FABP4 and LIPE

Number of citations of the paper that reports this interaction (PMID 10318917)
24

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		FABP4	LIPE
Gene Name		fatty acid binding protein 4, adipocyte	lipase, hormone-sensitive
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Lipid Particle Extracellular Vesicular Exosome	Lipid Particle Cytosol Caveola
	Molecular Function	Transporter Activity Fatty Acid Binding	Triglyceride Lipase Activity Protein Binding Protein Kinase Binding Hormone-sensitive Lipase Activity
	Biological Process	Cytokine Production Negative Regulation Of Protein Kinase Activity Transport Triglyceride Catabolic Process Cholesterol Homeostasis Small Molecule Metabolic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Inflammatory Response White Fat Cell Differentiation Brown Fat Cell Differentiation Cellular Response To Lithium Ion	Protein Phosphorylation Cholesterol Metabolic Process Lipid Catabolic Process Triglyceride Catabolic Process Long-chain Fatty Acid Catabolic Process Small Molecule Metabolic Process Diacylglycerol Catabolic Process
Pathways		Metabolism of lipids and lipoproteins Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis Transcriptional regulation of white adipocyte differentiation Lipid digestion, mobilization, and transport	Metabolism of lipids and lipoproteins Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis Lipid digestion, mobilization, and transport
Drugs
Diseases
GWAS		Ovarian cancer ( 23535730) Visceral fat ( 22589738)
Protein-Protein Interactions		8 interactors: ACP1 ACTB CHD3 INSR LIPE PRKCI VIM ZBED1	8 interactors: FABP4 KATNA1 MAPK1 MAPK3 NSFL1C PLIN1 PRKACA STAR
Entrez ID		2167	3991
HPRD ID		02698	01062
Ensembl ID		ENSG00000170323	ENSG00000079435
Uniprot IDs		E7DVW4 P15090	Q05469
PDB IDs		1TOU 1TOW 2HNX 2NNQ 3FR2 3FR4 3FR5 3P6C 3P6D 3P6E 3P6F 3P6G 3P6H 3Q6L 3RZY
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Glucose Import Positive Regulation Of Glucose Transport Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Glucose Import Regulation Of Glucose Transport Transformation Of Host Cell By Virus Diacylglycerol Catabolic Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway	Triglyceride Catabolic Process Cellular Response To Growth Hormone Stimulus Acylglycerol Catabolic Process Response To Growth Hormone Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Regulation Of Golgi Inheritance Caveolin-mediated Endocytosis Cellular Response To Peptide Hormone Stimulus Regulation Of Golgi Organization Cellular Response To Peptide Triglyceride Metabolic Process Vascular Endothelial Growth Factor Receptor Signaling Pathway Neutral Lipid Metabolic Process Regulation Of Early Endosome To Late Endosome Transport Response To Peptide Hormone Cellular Response To Organonitrogen Compound Response To Peptide Cellular Response To Epinephrine Stimulus Cellular Lipid Catabolic Process Cellular Response To Lipopolysaccharide Response To Epinephrine Cellular Response To Molecule Of Bacterial Origin Epidermal Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Cellular Response To Growth Factor Stimulus Cellular Response To Hormone Stimulus JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway Response To Growth Factor Platelet Activation Growth Hormone Receptor Signaling Pathway Cellular Response To Catecholamine Stimulus Neurotrophin TRK Receptor Signaling Pathway Cellular Response To Insulin Stimulus Response To Epidermal Growth Factor Regulation Of Cellular Response To Heat Neurotrophin Signaling Pathway Response To Cytokine Regulation Of Protein Kinase Activity Lipid Catabolic Process Lipopolysaccharide-mediated Signaling Pathway Regulation Of Kinase Activity Activation Of Protein Kinase Activity Innate Immune Response Response To Organonitrogen Compound Response To Insulin Regulation Of MAP Kinase Activity Peptidyl-threonine Phosphorylation Response To Exogenous DsRNA
Tagcloud ?		20th 80th associations bonferroni cept cholesterol comparing corrected determinant elucidated interactions ldl lipid lipids mechanistic nominal percentiles plasma polymorphisms rs1800774 rs2290201 sectional selenium selenoproteins share spain statistical statistically tg	abhd5 agpat2 anomaly atgl cgi ctgm dgat1 diverge enteropathy gk glycerol gpd1 hsl ichthyosis inborn jordan lipodystrophy loosing lpin1 lpin2 majeed nlsd perilipin pnpla2 pseudohypertriglyceridemia rhabdomyolysis steatosis tgs vacuolated
Tagcloud (Difference) ?		20th 80th associations bonferroni cept cholesterol comparing corrected determinant elucidated interactions ldl lipid lipids mechanistic nominal percentiles plasma polymorphisms rs1800774 rs2290201 sectional selenium selenoproteins share spain statistical statistically tg	abhd5 agpat2 anomaly atgl cgi ctgm dgat1 diverge enteropathy gk glycerol gpd1 hsl ichthyosis inborn jordan lipodystrophy loosing lpin1 lpin2 majeed nlsd perilipin pnpla2 pseudohypertriglyceridemia rhabdomyolysis steatosis tgs vacuolated
Tagcloud (Intersection) ?