SH2B2 and INSR

  • Number of citations of the paper that reports this interaction (PMID 10196204)
  • 25
  • Data Source:
  • HPRD (in vitro)

SH2B2

INSR

Gene Name SH2B adaptor protein 2 insulin receptor
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 21 interactors: AKT1 ASB6 BTK CBL EPOR ERBB2 FYN GRB2 INSR JAK1 JAK2 JAK3 KIT LYN NTRK1 NTRK2 PDLIM7 SH2B1 SHC1 SORBS1 SYK 77 interactors: ACP1 ADRB2 AHSG ARF1 ARHGAP26 CALM1 CALM2 CALM3 CAV1 CAV3 CBL CEACAM1 CRK CRKL CSK DOK1 DOK4 DOK5 ENPP1 FABP4 FRS2 GAB1 GNB2L1 GRB10 GRB14 GRB7 HRAS IGF1R IGF2 INS INSRR IRF7 IRS1 IRS2 JAK1 JAK2 KHDRBS1 KRT27 KRT31 MAD2L1 MAPK3 PIK3R1 PIK3R3 PLCG1 PRKCA PRKCD PTK2 PTPN1 PTPN11 PTPN12 PTPN2 PTPN6 PTPRC PTPRF RAF1 RASA1 SH2B1 SH2B2 SHC1 SMAD2 SNX1 SNX2 SNX4 SNX6 SOCS1 SOCS2 SOCS3 SOCS6 SORBS1 SRC STAT5A STAT5B SYNCRIP TEAD1 VAV1 VAV3 YWHAB
Entrez ID 10603 3643
HPRD ID 16097 00975
Ensembl ID ENSG00000171105
Uniprot IDs O14492 P06213
PDB IDs 1Q2H 1GAG 1I44 1IR3 1IRK 1P14 1RQQ 2AUH 2B4S 2DTG 2HR7 2Z8C 3BU3 3BU5 3BU6 3EKK 3EKN 3ETA 3LOH 3W11 3W12 3W13 3W14 4IBM
Enriched GO Terms of Interacting Partners?
Tagcloud ?
accordingly  adaptor  aps  assembling  called  counteract  dephosphorylation  dimerization  dimers  hetero  homo  hyperphagia  insects  irs1  irs2  leptin  obesity  protecting  protects  psm  sh2b1  sh2b1beta  sh2b3  transgenes  trka  tyrosyl 
birthweight  cognate  curly  delays  determinant  dwarfing  edema  eliminated  embryogenesis  embryos  epidermis  generalized  hypoplasia  igf1r  igf2  igr1r  indistinguishable  manifested  mildly  muscles  nullizygotes  nullizygous  ossification  phenotypically  recognizes  retardation  solely  thin  xr 
Tagcloud (Difference) ?
accordingly  adaptor  aps  assembling  called  counteract  dephosphorylation  dimerization  dimers  hetero  homo  hyperphagia  insects  irs1  irs2  leptin  obesity  protecting  protects  psm  sh2b1  sh2b1beta  sh2b3  transgenes  trka  tyrosyl 
birthweight  cognate  curly  delays  determinant  dwarfing  edema  eliminated  embryogenesis  embryos  epidermis  generalized  hypoplasia  igf1r  igf2  igr1r  indistinguishable  manifested  mildly  muscles  nullizygotes  nullizygous  ossification  phenotypically  recognizes  retardation  solely  thin  xr 
Tagcloud (Intersection) ?