TUBB3 and CAMSAP3

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
HPRD (two hybrid)

		TUBB3	CAMSAP3
Description		tubulin beta 3 class III	calmodulin regulated spectrin associated protein family member 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytoskeleton Microtubule Microtubule Cytoskeleton Lamellipodium Filopodium Axon Dendrite Growth Cone Cell Projection Neuronal Cell Body Intercellular Bridge Extracellular Exosome Cell Periphery Mitotic Spindle	Cytoplasm Centrosome Cytoskeleton Microtubule Adherens Junction Zonula Adherens Axoneme Microtubule Cytoskeleton Replication Fork Protection Complex Motile Cilium Ciliary Basal Body Microtubule Minus-end Cell Projection Anchoring Junction
	Molecular Function	Nucleotide Binding GTPase Activity Structural Constituent Of Cytoskeleton Protein Binding GTP Binding Peptide Binding Metal Ion Binding Netrin Receptor Binding	DNA Binding Protein Binding Calmodulin Binding Microtubule Binding Spectrin Binding Microtubule Minus-end Binding Actin Filament Binding
	Biological Process	Microtubule Cytoskeleton Organization Mitotic Cell Cycle Microtubule-based Process Axon Guidance Neuron Differentiation Netrin-activated Signaling Pathway Dorsal Root Ganglion Development	DNA Replication Checkpoint Signaling Microtubule Cytoskeleton Organization In Utero Embryonic Development Cilium Movement Embryo Development Ending In Birth Or Egg Hatching Cell Projection Organization Regulation Of Cell Migration Establishment Or Maintenance Of Microtubule Cytoskeleton Polarity Regulation Of Microtubule Polymerization Neuron Projection Development Regulation Of Organelle Organization Microtubule Anchoring Replication Fork Arrest Establishment Of Epithelial Cell Apical/basal Polarity Zonula Adherens Maintenance Regulation Of Focal Adhesion Assembly Regulation Of Microtubule Cytoskeleton Organization Epithelial Cell-cell Adhesion Protein Transport Along Microtubule Regulation Of Golgi Organization
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane Gap junction assembly MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand Recruitment of NuMA to mitotic centrosomes Prefoldin mediated transfer of substrate to CCT/TriC Formation of tubulin folding intermediates by CCT/TriC Post-chaperonin tubulin folding pathway Recycling pathway of L1 Recycling pathway of L1 Hedgehog 'off' state Cargo trafficking to the periciliary membrane Intraflagellar transport RHO GTPases activate IQGAPs RHO GTPases Activate Formins COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic COPI-independent Golgi-to-ER retrograde traffic Mitotic Prometaphase The role of GTSE1 in G2/M progression after G2 checkpoint Carboxyterminal post-translational modifications of tubulin Carboxyterminal post-translational modifications of tubulin HCMV Early Events Assembly and cell surface presentation of NMDA receptors Activation of AMPK downstream of NMDARs Aggrephagy Aggrephagy EML4 and NUDC in mitotic spindle formation Sealing of the nuclear envelope (NE) by ESCRT-III Kinesins PKR-mediated signaling
Drugs		Epothilone D Patupilone Ixabepilone CYT997 ZEN-012 Phenethyl Isothiocyanate
Diseases		Congenital fibrosis of the extraocular muscles (CFEOM)
GWAS		Brain morphology (MOSTest) ( 32665545) Cutaneous malignant melanoma ( 32341527) Cutaneous squamous cell carcinoma ( 32041948) Left-handedness ( 32989287) Left–right brain asymmetry ( 33723403) Liver fibrogenesis (alpha smooth muscle actin levels) ( 32953199) Obsessive-compulsive disorder or autism spectrum disorder ( 28641744) Red vs. brown/black hair color ( 30531825) Rosacea symptom severity ( 29771307) Squamous cell carcinoma ( 31174203)	Diffusing capacity of carbon monoxide ( 30694715)
Interacting Genes		38 interacting genes: ABCC2 ANXA7 ARHGEF7 CAMSAP3 CDC42 CDKN1A DDX39B DUX4 EEF1G GABARAP GZMK HEXD INSM1 KHDRBS1 LAPTM4A LIG1 LINC01554 MAP7D3 MAPT MRPL28 MTCL1 MTDH OGT PHIP PLK1 RCC1 RILPL2 ROBO1 RSPH1 SCGN SEL1L3 SMN1 SPTSSA TERF1 TF TK1 TPTE WEE2-AS1	7 interacting genes: DHX15 FSD2 GSK3B HSF2BP KATNA1 KATNB1 TUBB3
Entrez ID		10381	57662
HPRD ID		04044	13871
Ensembl ID		ENSG00000258947	ENSG00000076826
Uniprot IDs		Q13509 Q53G92	Q9P1Y5
PDB IDs		5IJ0 5IJ9 5JCO 6E7B 6S8L 6WSL 7LXB 7M18 7M20 7PJF 7SJ7 7SJ8 7SJ9 7SJA 7Z6S 8VRJ 8VRK 8VT7
Enriched GO Terms of Interacting Partners?		Microtubule Binding Regulation Of Protein-containing Complex Assembly Microtubule Cytoskeleton Organization Regulation Of Protein Localization To Synapse Regulation Of Cell Cycle Process Regulation Of Microtubule Cytoskeleton Organization Intercellular Canaliculus Regulation Of Protein K48-linked Ubiquitination Cytoskeleton Organization Microtubule-based Process Regulation Of Protein Modification Process Organelle Organization Establishment Or Maintenance Of Apical/basal Cell Polarity Regulation Of Mitotic Nuclear Division Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Regulation Of Cell Cycle Negative Regulation Of DNA Metabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Nuclear Division Regulation Of Microtubule-based Process Cellular Component Assembly Mitotic Cell Cycle Phase Transition	Katanin Complex Microtubule Severing Regulation Of Microtubule Cytoskeleton Organization Positive Regulation Of Binding Regulation Of Microtubule-based Process Microtubule Cytoskeleton Regulation Of Microtubule Anchoring At Centrosome Excitatory Postsynaptic Potential Hepatocyte Growth Factor Receptor Activity Cytoplasmic Microtubule Organization Microtubule Nucleotide Binding Axon Superior Temporal Gyrus Development Negative Regulation Of Type B Pancreatic Cell Development Negative Regulation Of Mesenchymal Stem Cell Differentiation Negative Regulation Of Glycogen (starch) Synthase Activity ATPase Regulator Activity Netrin Receptor Binding Regulation Of Postsynaptic Membrane Potential Regulation Of Microtubule Polymerization Or Depolymerization Microtubule Cytoskeleton Organization U2-type Post-mRNA Release Spliceosomal Complex Positive Regulation Of Organelle Organization Beta-arrestin-dependent Dopamine Receptor Signaling Pathway Negative Regulation Of TORC2 Signaling Negative Regulation Of Dopaminergic Neuron Differentiation Regulation Of Cytoskeleton Organization Regulation Of Glycogen (starch) Synthase Activity Pyrimidine Dimer Repair By Nucleotide-excision Repair Post-embryonic Camera-type Eye Morphogenesis Negative Regulation Of Thrombin-activated Receptor Signaling Pathway Negative Regulation Of Guanyl-nucleotide Exchange Factor Activity Positive Regulation Of Microtubule Depolymerization Mitotic Chromosome Movement Towards Spindle Pole Growth Cone Mitotic Spindle Dorsal Root Ganglion Development Negative Regulation Of Cytoskeleton Organization Negative Regulation Of Supramolecular Fiber Organization Spindle Pole Positive Regulation Of Protein Localization To Cilium Microtubule Severing ATPase Activity Cellular Response To Interleukin-3 Positive Regulation Of Protein Localization To Centrosome Post-embryonic Eye Morphogenesis Positive Regulation Of Supramolecular Fiber Organization Female Meiosis I ATP Binding Centrosome
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