SDHAF2 and SEC22A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SDHAF2	SEC22A
Description		succinate dehydrogenase complex assembly factor 2	SEC22 homolog A, vesicle trafficking protein
Image			No pdb structure
GO Annotations	Cellular Component	Nucleolus Mitochondrion Mitochondrial Matrix Cytosol	Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Protein Binding	SNAP Receptor Activity Protein Binding
	Biological Process	Tricarboxylic Acid Cycle Mitochondrial Electron Transport, Succinate To Ubiquinone Protein Dephosphorylation Negative Regulation Of Epithelial To Mesenchymal Transition Protein-FAD Linkage Mitochondrial Respiratory Chain Complex II Assembly Negative Regulation Of Canonical Wnt Signaling Pathway	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Protein Transport Vesicle-mediated Transport Membrane Fusion
Pathways		Maturation of TCA enzymes and regulation of TCA cycle	COPII-mediated vesicle transport
Drugs
Diseases
GWAS			Gestational age at birth (maternal effect) ( 28877031)
Interacting Genes		6 interacting genes: CCDC90B CYP4F2 EEF1A1 ELP1 IMMT SEC22A	108 interacting genes: ADGRG3 AQP6 ASGR2 ATP6AP2 BIK BNIP3 C10orf67 C16orf54 C16orf92 CALN1 CD207 CD300A CD7 CD74 CISD2 CLEC10A CLEC12B CLEC2D CLEC7A CREB3L1 CYB561 CYBRD1 DDIT4L DIABLO DTX2 EDA ELOVL4 ERLIN1 ERVFRD-1 FAM174A FAM209A FATE1 FUT3 GAD2 GGT6 GJB5 GJB6 GPR37L1 GRAMD2B HAVCR2 HCST HSD17B11 ICAM3 KCNJ2 LDAF1 LDLRAD1 LHFPL5 LMNA LPAR6 LRRC25 LSMEM2 MCOLN1 MFF MGST2 MINAR1 MS4A14 MS4A3 MS4A4A MSR1 OPRM1 PACC1 PEX12 PHB1 PTGES RASGRP4 RETREG3 RILPL1 RNASEK RNF144A RNF19B RNF5 SAR1A SCN3B SDHAF2 SFTPC SLC10A1 SLC14A2 SLC18A1 SLC30A2 SLC35H1 SLC39A2 SMIM3 SPAG4 STMN4 STOML3 STX1A STX2 STX4 SUSD3 SYNE4 TFR2 TLCD4 TMED9 TMEM106C TMEM174 TMEM237 TMEM45B TMEM52B TMEM71 TMEM79 TMIE TMPRSS2 TNFSF14 TP53INP1 TRAT1 TRIM59 TYRP1 ZFYVE27
Entrez ID		54949	26984
HPRD ID		07915	15313
Ensembl ID		ENSG00000167985	ENSG00000121542
Uniprot IDs		Q9NX18	Q96IW7
PDB IDs		6VAX 8DYD
Enriched GO Terms of Interacting Partners?		TRNA Binding Eukaryotic Translation Elongation Factor 1 Complex TRNA Wobble Base 5-methoxycarbonylmethyl-2-thiouridinylation Elongator Holoenzyme Complex Alpha-tocopherol Omega-hydroxylase Activity Negative Regulation Of Icosanoid Secretion Phylloquinone Catabolic Process Long-chain Fatty Acid Omega-hydroxylase Activity Leukotriene B4 Catabolic Process Vitamin K Catabolic Process 20-hydroxy-leukotriene B4 Omega Oxidase Activity Vitamin E Metabolic Process Alkane 1-monooxygenase Activity Menaquinone Metabolic Process 20-aldehyde-leukotriene B4 20-monooxygenase Activity Fatty Acid Omega-oxidation Leukotriene B4 Metabolic Process Arachidonate Omega-hydroxylase Activity Leukotriene-B4 20-monooxygenase Activity Pressure Natriuresis Menaquinone Catabolic Process Mitochondrial Crista Junction MICOS Complex Regulation Of Chaperone-mediated Autophagy Long-chain Fatty Acid Catabolic Process Negative Regulation Of Fatty Acid Transport Host-mediated Activation Of Viral Genome Replication Arachidonate Epoxygenase Activity Omega-hydroxylase P450 Pathway SAM Complex MIB Complex Host-mediated Perturbation Of Viral Genome Replication Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, NAD(P)H As One Donor, And Incorporation Of One Atom Of Oxygen Cristae Formation Kinase Activator Activity Cytoplasmic Side Of Lysosomal Membrane Vitamin K Metabolic Process TRNA Wobble Uridine Modification Epoxygenase P450 Pathway Mitochondrial Envelope Positive Regulation Of Icosanoid Secretion Ketone Catabolic Process Translation Elongation Factor Activity Renal Water Homeostasis Renal System Process Involved In Regulation Of Systemic Arterial Blood Pressure Positive Regulation Of Fatty Acid Transport Mitochondrial Calcium Ion Homeostasis Inorganic Ion Homeostasis Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, Reduced Flavin Or Flavoprotein As One Donor, And Incorporation Of One Atom Of Oxygen Vitamin Metabolic Process	Membrane Protein Binding Plasma Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Lysosomal Membrane PH-gated Chloride Channel Activity Transmembrane Transport Pattern Recognition Receptor Activity Ascorbate Homeostasis Icosanoid Biosynthetic Process Endoplasmic Reticulum-autophagosome Adaptor Activity Transmembrane Monodehydroascorbate Reductase Activity D-mannose Binding
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?