CTBP1 and RIPK4

Number of citations of the paper that reports this interaction (PubMedID 35914814)
83

Data Source:
BioGRID (two hybrid)

		CTBP1	RIPK4
Description		C-terminal binding protein 1	receptor interacting serine/threonine kinase 4
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Transcription Repressor Complex Presynaptic Active Zone Cytoplasmic Component Glutamatergic Synapse GABA-ergic Synapse	Cytoplasm Cytosol Plasma Membrane Membrane
	Molecular Function	Transcription Coregulator Binding Transcription Corepressor Binding Chromatin Binding Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Oxidoreductase Activity Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor Protein Domain Specific Binding Identical Protein Binding NAD Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding LncRNA Binding DNA-binding Transcription Factor Binding	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Protein Serine Kinase Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Protein Phosphorylation Notch Signaling Pathway Negative Regulation Of Cell Population Proliferation Viral Genome Replication Cell Differentiation Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Synaptic Vesicle Endocytosis White Fat Cell Differentiation Regulation Of Cell Cycle Synaptic Vesicle Clustering	Morphogenesis Of An Epithelium Skin Development Positive Regulation Of NF-kappaB Transcription Factor Activity
Pathways		Deactivation of the beta-catenin transactivating complex SUMOylation of transcription cofactors Repression of WNT target genes Signaling by TCF7L2 mutants Negative Regulation of CDH1 Gene Transcription
Drugs		Formic acid
Diseases
GWAS		Type 2 diabetes ( 31118516 32499647)	Femur bone mineral density x serum urate levels interaction ( 34046847) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)
Interacting Genes		101 interacting genes: ACTL6B AKAP9 APC ARNT2 ATXN1L BCAS3 BCL3 BMPR2 BRCA1 CBX4 CCDC9 CDC23 CDKN2D CEP68 CHD3 CPSF7 CREBBP CRY2 CTBP2 CTNNA1 DCAF6 DGCR6 DMRTB1 EEF1D ELAC2 ELK3 EP300 FANCC FANCF FANCG FANCL FOXP1 FUNDC1 GNL3L GTF2B H2AX H3-4 HDAC1 HDAC2 HDAC3 HDAC4 HDAC5 HDAC9 HEMGN HIC1 HOXB5 HTT IKZF1 IKZF2 KAT2B KLF12 LNX1 MAML2 MAPK9 MARCHF10 MECOM NME2 NOL4 NOL4L NOS1 NRIP1 NTAQ1 ORC4 PIAS2 PKP2 PLCB1 PNN PRKAA1 PRKCI PRPF19 PRPF6 PRRC2B RAI2 RB1 RBBP5 RBBP8 RBM14 RBM22 RIPK4 RNF111 SART3 SF1 SIN3A SNRPN SNW1 SOBP SPEN TBP TCF4 TEAD4 TERF2 TERF2IP TGIF1 TSHZ3 UNKL ZBP1 ZEB1 ZEB2 ZFPM2 ZNF219 ZNF750	38 interacting genes: ANK2 ANK3 ANKRD6 ASB3 BIRC2 BIRC3 BTRC CARS2 CLTC CTBP1 FBXW11 GPSM3 HSPA5 KPNA1 LINC01537 MACF1 MAGI2 MIB1 MICU1 MTPN MYO1E NAPA PADI2 PREPL PRKCB PRKCD PTPRK RPL13 SPAG8 SPAST STAM TNPO2 TRAF7 UBE4B VCP VWC2L WDR19 XIAP
Entrez ID		1487	54101
HPRD ID		04015	10419
Ensembl ID		ENSG00000159692	ENSG00000183421
Uniprot IDs		H0Y8U5 Q13363 X5D8Y5	Q96T11 Q9H4D1
PDB IDs		1MX3 4LCE 4U6Q 4U6S 6CDF 6CDR 6V89 6V8A 7KWM 8ARI
Enriched GO Terms of Interacting Partners?		Nucleoplasm Nucleus Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Chromatin Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of RNA Metabolic Process Negative Regulation Of RNA Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Regulation Of Primary Metabolic Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression Regulation Of Macromolecule Metabolic Process Transcription Corepressor Activity Negative Regulation Of Macromolecule Biosynthetic Process DNA Binding Negative Regulation Of Transcription By RNA Polymerase II DNA-binding Transcription Factor Binding Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Macromolecule Metabolic Process Negative Regulation Of Biosynthetic Process Positive Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Metabolic Process Histone Deacetylase Complex Chromatin Remodeling Nuclear Speck RNA Polymerase II-specific DNA-binding Transcription Factor Binding Histone Deacetylase Activity, Hydrolytic Mechanism Chromatin Organization Negative Regulation Of Metabolic Process Protein Lysine Deacetylase Activity Epigenetic Regulation Of Gene Expression Regulation Of Cell Differentiation Cellular Response To Stress Histone Deacetylase Activity Chromatin Binding Negative Regulation Of Gene Expression, Epigenetic Histone Deacetylase Binding Nucleic Acid Metabolic Process Transcription Coactivator Activity	Cytoplasm Canonical NF-kappaB Signal Transduction Cellular Localization Signal Transduction Vesicle-mediated Transport Intracellular Protein Localization Protein Transport Regulation Of Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process Protein Ubiquitination Post-translational Protein Modification Positive Regulation Of Post-translational Protein Modification Intracellular Signaling Cassette Establishment Of Protein Localization Ubiquitin Protein Ligase Activity Mitotic Spindle Disassembly Protein Modification By Small Protein Conjugation Ubiquitin-protein Transferase Activity Protein Modification Process Protein Kinase C Signaling Golgi Vesicle Transport Protein Polyubiquitination Intracellular Transport Regulation Of Cell Communication Non-canonical NF-kappaB Signal Transduction Cell Surface Receptor Signaling Pathway Protein Localization To Membrane Positive Regulation Of Protein Metabolic Process Protein Metabolic Process Golgi To Plasma Membrane Protein Transport Regulation Of Canonical NF-kappaB Signal Transduction Intracellular Signal Transduction Regulation Of Wnt Signaling Pathway Establishment Of Localization In Cell Positive Regulation Of Protein Ubiquitination Channel Activator Activity Proteolysis Involved In Protein Catabolic Process Protein Localization To Cell Periphery Positive Regulation Of Canonical NF-kappaB Signal Transduction Positive Regulation Of Macromolecule Metabolic Process Intracellular Protein Transport Negative Regulation Of Signal Transduction Regulation Of Post-translational Protein Modification Cytosol Ubiquitin-dependent Protein Catabolic Process Regulation Of Canonical Wnt Signaling Pathway Modification-dependent Protein Catabolic Process Cytoskeleton Positive Regulation Of Membrane Potential Establishment Of Protein Localization To Plasma Membrane
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?