CSTF2 and CHD3

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		CSTF2	CHD3
Gene Name		cleavage stimulation factor, 3 pre-RNA, subunit 2, 64kDa	chromodomain helicase DNA binding protein 3
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm MRNA Cleavage And Polyadenylation Specificity Factor Complex Cleavage Body	Nucleus Nucleoplasm Nucleolus Cytoplasm Centrosome NuRD Complex Intermediate Filament Cytoskeleton
	Molecular Function	Nucleotide Binding RNA Binding Protein Binding Poly(A) RNA Binding	DNA Binding ATP-dependent DNA Helicase Activity Helicase Activity Protein Binding ATP Binding Zinc Ion Binding Poly(A) RNA Binding
	Biological Process	MRNA Splicing, Via Spliceosome Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription MRNA Polyadenylation MRNA Cleavage RNA Splicing Gene Expression MRNA 3'-end Processing	Chromatin Organization Chromatin Assembly Or Disassembly Transcription, DNA-templated Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Spindle Organization Chromatin Modification DNA Duplex Unwinding Centrosome Organization
Pathways		mRNA Splicing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Processing of Capped Intronless Pre-mRNA mRNA Splicing - Major Pathway Cleavage of Growing Transcript in the Termination Region RNA Polymerase II Transcription Termination mRNA 3'-end processing Processing of Intronless Pre-mRNAs	Chromatin modifying enzymes Chromatin organization HDACs deacetylate histones RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase I Transcription RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Clearance
Drugs
Diseases
GWAS
Protein-Protein Interactions		23 interactors: APP BAG6 C14orf1 CHD3 CSTF3 DDX1 ECH1 EEF1G FEZ1 HGS IKBKAP IMMT KAT5 KIAA1377 POLR2A SPAG8 SS18L1 SUB1 SYMPK TFG UBQLN1 UBQLN4 ZNF341	90 interactors: ACTR1B ADH5 AIMP2 ATPIF1 BARD1 BCL6 BHLHE40 C4orf17 CASP6 CASP8 CPE CRCT1 CREB1 CSTF2 CTBP1 CTTN FABP4 FAM134A FBP2 FUBP1 GADD45A GIT1 GPS2 GSK3B HABP4 HSD17B10 HSPH1 HTT IK IKZF1 IKZF3 IMMT IVNS1ABP KIF15 KPNA2 KPNB1 LRIF1 LUC7L2 MAFG MAN2A2 MYB NEFL NR1H2 NR4A1 PAICS PCMT1 PIAS4 PLK4 PRG2 PRPF40A PSME1 PTN PTPRS PUF60 RAD51 RGS2 RIF1 RPL29 SAFB SAT1 SATB1 SDCCAG3 SERBP1 SERF2 SGSM2 SIRT6 SKIL SLC27A6 SRRT SUMO1 SUMO2 TAL1 TCERG1 THOC7 TNFRSF14 TNNT1 TP53 TP73 TRIM28 TSC22D1 TSPAN6 TTR TXNDC9 UBA3 UBE2I UROD VIM XRCC4 YAE1D1 ZHX1
Entrez ID		1478	1107
HPRD ID		02652	09071
Ensembl ID		ENSG00000101811	ENSG00000170004
Uniprot IDs		E7EWR4 P33240	B3KWV4 Q12873 Q2TAZ1
PDB IDs		1P1T 2J8P
Enriched GO Terms of Interacting Partners?		MRNA Polyadenylation Gene Expression RNA Polyadenylation RNA Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process MRNA Processing MRNA 3'-end Processing Regulation Of Protein Metabolic Process MRNA Metabolic Process RNA 3'-end Processing Regulation Of Gene Expression Regulation Of Metabolic Process RNA Processing Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Chromosome Organization Regulation Of Cellular Protein Metabolic Process Nucleobase-containing Compound Metabolic Process Positive Regulation Of Gene Expression Chromatin Organization Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Transcription Elongation From RNA Polymerase II Promoter Transcription, RNA-templated Synaptic Growth At Neuromuscular Junction Nitrogen Compound Metabolic Process Regulation Of Dendrite Morphogenesis Positive Regulation Of Macromolecule Biosynthetic Process Chromatin Modification Regulation Of Epidermal Growth Factor Receptor Signaling Pathway DNA Duplex Unwinding DNA Geometric Change Regulation Of ERBB Signaling Pathway Collateral Sprouting In Absence Of Injury DNA-templated Transcription, Elongation Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Biosynthetic Process RNA Splicing Regulation Of Dendrite Development Collateral Sprouting Axon Midline Choice Point Recognition	Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Metabolic Process RNA Metabolic Process RNA Biosynthetic Process Transcription, DNA-templated Negative Regulation Of Gene Expression Viral Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Cellular Metabolic Process Negative Regulation Of RNA Biosynthetic Process Gene Expression Negative Regulation Of Biosynthetic Process Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Apoptotic Process Biosynthetic Process Protein Sumoylation Macromolecule Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cell Death Regulation Of Cellular Process Positive Regulation Of Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Cell Cycle Positive Regulation Of Organelle Organization Regulation Of Cell Differentiation Negative Regulation Of Programmed Cell Death Positive Regulation Of Apoptotic Process Regulation Of Gene Expression Positive Regulation Of Programmed Cell Death B Cell Activation Cellular Process Negative Regulation Of Cell Death Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Positive Regulation Of Cell Death Programmed Cell Death Cell Differentiation Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Cell Death Negative Regulation Of Apoptotic Process Death Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Immune System Process
Tagcloud ?			ancestor animal arabidopsis atp codes deacetylation exhibits exists mi monomer mononucleosomes multisubunit naked nurd pickle planta promotes remodeler remodelers remodeling restrict retain share ssdna subfamily thaliana trimethylation ubiquitous
Tagcloud (Difference) ?			ancestor animal arabidopsis atp codes deacetylation exhibits exists mi monomer mononucleosomes multisubunit naked nurd pickle planta promotes remodeler remodelers remodeling restrict retain share ssdna subfamily thaliana trimethylation ubiquitous
Tagcloud (Intersection) ?