CSTF2 and METTL27

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CSTF2	METTL27
Description		cleavage stimulation factor subunit 2	methyltransferase like 27
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm MRNA Cleavage And Polyadenylation Specificity Factor Complex Nuclear Body Cleavage Body
	Molecular Function	Nucleic Acid Binding RNA Binding MRNA Binding Protein Binding	Protein Binding
	Biological Process	MRNA Processing MRNA 3'-end Processing Cellular Response To Nerve Growth Factor Stimulus
Pathways		tRNA processing in the nucleus mRNA 3'-end processing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs
Drugs
Diseases
GWAS
Interacting Genes		48 interacting genes: ABHD11 AKAP8L ANKRD10 APP ATP23 BAG6 CDSN CEACAM6 CEP126 CHD3 CNOT2 CSTF3 CTBP2 DDX1 ECH1 EEF1G ELP1 ERG28 FAM168B FEZ1 HDHD3 HGS IMMT INCA1 KAT5 METTL15 METTL27 MIR19A MIR92A2 POLR2A POU6F2 PRDM6 RFX6 SAXO4 SPAG8 SS18L1 STH SUB1 SYMPK TFG TLE3 TLE5 TSC1 UBQLN1 UBQLN4 UFSP1 USP54 ZNF341	29 interacting genes: A1CF ATXN1 ATXN1L CCDC120 CSTF2 DOK6 EFHC1 ENKD1 FOXC2 GLYCTK GPANK1 GRB2 HGS KDM1A LMO4 NOXA1 PITX1 PRKAB2 PRMT6 PROP1 SAXO4 SNRPC TBX6 TEKT3 TFG TLX3 VPS37C ZIC1 ZNF77
Entrez ID		1478	155368
HPRD ID		02652	15661
Ensembl ID		ENSG00000101811	ENSG00000165171
Uniprot IDs		B3V096 B4DUD5 E7EWR4 P33240	Q8N6F8
PDB IDs		1P1T 2J8P 6Q2I 6TZE
Enriched GO Terms of Interacting Partners?			POZ Domain Binding Axonemal A Tubule Inner Sheath Negative Regulation Of RNA Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of RNA Biosynthetic Process Sequence-specific Double-stranded DNA Binding Regulation Of Transcription By RNA Polymerase II Cell Fate Specification Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
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