CSTF2 and IMMT

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CSTF2	IMMT
Gene Name		cleavage stimulation factor, 3 pre-RNA, subunit 2, 64kDa	inner membrane protein, mitochondrial
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm MRNA Cleavage And Polyadenylation Specificity Factor Complex Cleavage Body	Mitochondrion Mitochondrial Inner Membrane Membrane Integral Component Of Membrane
	Molecular Function	Nucleotide Binding RNA Binding Protein Binding Poly(A) RNA Binding	Protein Binding Poly(A) RNA Binding
	Biological Process	MRNA Splicing, Via Spliceosome Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription MRNA Polyadenylation MRNA Cleavage RNA Splicing Gene Expression MRNA 3'-end Processing	Biological_process Response To Cold Mitochondrial Calcium Ion Homeostasis
Pathways		mRNA Splicing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Processing of Capped Intronless Pre-mRNA mRNA Splicing - Major Pathway Cleavage of Growing Transcript in the Termination Region RNA Polymerase II Transcription Termination mRNA 3'-end processing Processing of Intronless Pre-mRNAs
Drugs
Diseases
GWAS
Protein-Protein Interactions		23 interactors: APP BAG6 C14orf1 CHD3 CSTF3 DDX1 ECH1 EEF1G FEZ1 HGS IKBKAP IMMT KAT5 KIAA1377 POLR2A SPAG8 SS18L1 SUB1 SYMPK TFG UBQLN1 UBQLN4 ZNF341	58 interactors: AKTIP ALB ARMCX3 ASCC2 ATXN1 BAG6 BMI1 C10orf88 C8orf33 CALM1 CCDC113 CCT5 CDC37 CHD3 CSTF2 DISC1 ECSIT EEF1A1 EP300 EXOSC10 FAM173A FEZ1 FUBP1 HAP1 HIVEP1 HJURP HMOX2 HNRNPD KDM1A KIF22 KPNA2 LRIF1 MRPL44 NDEL1 NDUFB9 NEK2 NIPSNAP3A NOS3 PDE4DIP PFDN1 PIAS4 PLA2G15 PPOX PRRC2A RER1 SDHAF2 SMN1 SNAPIN SRRT STMN4 STX5 TAF1D TK1 TNNT1 TRAF3IP1 TUBGCP3 TXNDC9 UBQLN4
Entrez ID		1478	10989
HPRD ID		02652	02658
Ensembl ID		ENSG00000101811	ENSG00000132305
Uniprot IDs		E7EWR4 P33240	B9A067 Q16891
PDB IDs		1P1T 2J8P
Enriched GO Terms of Interacting Partners?		MRNA Polyadenylation Gene Expression RNA Polyadenylation RNA Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process MRNA Processing MRNA 3'-end Processing Regulation Of Protein Metabolic Process MRNA Metabolic Process RNA 3'-end Processing Regulation Of Gene Expression Regulation Of Metabolic Process RNA Processing Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Chromosome Organization Regulation Of Cellular Protein Metabolic Process Nucleobase-containing Compound Metabolic Process Positive Regulation Of Gene Expression Chromatin Organization Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Transcription Elongation From RNA Polymerase II Promoter Transcription, RNA-templated Synaptic Growth At Neuromuscular Junction Nitrogen Compound Metabolic Process Regulation Of Dendrite Morphogenesis Positive Regulation Of Macromolecule Biosynthetic Process Chromatin Modification Regulation Of Epidermal Growth Factor Receptor Signaling Pathway DNA Duplex Unwinding DNA Geometric Change Regulation Of ERBB Signaling Pathway Collateral Sprouting In Absence Of Injury DNA-templated Transcription, Elongation Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Biosynthetic Process RNA Splicing Regulation Of Dendrite Development Collateral Sprouting Axon Midline Choice Point Recognition	Organelle Organization Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Localization Nucleobase-containing Compound Metabolic Process Transcription, DNA-templated Microtubule-based Process RNA Metabolic Process RNA Biosynthetic Process Gene Expression Regulation Of Binding Regulation Of Metabolic Process Cellular Metabolic Process Posttranscriptional Regulation Of Gene Expression Establishment Of Localization In Cell Microtubule Polymerization Or Depolymerization Retrograde Axon Cargo Transport Regulation Of Gene Expression, Epigenetic Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cell Cycle Cellular Macromolecule Biosynthetic Process Chromosome Segregation Embryo Development Cellular Process Macromolecule Biosynthetic Process Axon Cargo Transport Regulation Of Protein Metabolic Process Microtubule-based Transport RNA Processing Brain Development Cytoskeleton-dependent Intracellular Transport Centrosome Separation Embryo Development Ending In Birth Or Egg Hatching Organelle Localization Nervous System Development Chromosome Organization Regulation Of Protein Binding Head Development Anatomical Structure Development Regulation Of Cellular Process Microtubule Cytoskeleton Organization Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Biosynthetic Process Microtubule-based Movement Regulation Of Oxidoreductase Activity Regulation Of RNA Metabolic Process Establishment Of Organelle Localization
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