CSTF2 and CSTF3

Number of citations of the paper that reports this interaction (PubMedID 31839598)
57

Data Source:
BioGRID (cross-linking study)
HPRD (in vitro)

		CSTF2	CSTF3
Description		cleavage stimulation factor subunit 2	cleavage stimulation factor subunit 3
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm MRNA Cleavage And Polyadenylation Specificity Factor Complex Nuclear Body Cleavage Body	Nucleus Nucleoplasm MRNA Cleavage Stimulating Factor Complex
	Molecular Function	Nucleic Acid Binding RNA Binding MRNA Binding Protein Binding	RNA Binding MRNA Binding Protein Binding
	Biological Process	MRNA Processing MRNA 3'-end Processing Cellular Response To Nerve Growth Factor Stimulus	RNA Processing MRNA Processing RNA 3'-end Processing MRNA 3'-end Processing Co-transcriptional MRNA 3'-end Processing, Cleavage And Polyadenylation Pathway
Pathways		tRNA processing in the nucleus mRNA 3'-end processing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs	mRNA 3'-end processing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs
Drugs
Diseases
GWAS			Anger ( 24489884) Non-response to citalopram or escitalopram and depression ( 27622933)
Interacting Genes		48 interacting genes: ABHD11 AKAP8L ANKRD10 APP ATP23 BAG6 CDSN CEACAM6 CEP126 CHD3 CNOT2 CSTF3 CTBP2 DDX1 ECH1 EEF1G ELP1 ERG28 FAM168B FEZ1 HDHD3 HGS IMMT INCA1 KAT5 METTL15 METTL27 MIR19A MIR92A2 POLR2A POU6F2 PRDM6 RFX6 SAXO4 SPAG8 SS18L1 STH SUB1 SYMPK TFG TLE3 TLE5 TSC1 UBQLN1 UBQLN4 UFSP1 USP54 ZNF341	15 interacting genes: CEBPA CSTF1 CSTF2 DLGAP1-AS2 MIR128-2 MIR138-2 MIR15B MIR19A MIR19B1 MIR21 MIR92A2 MIRLET7A3 MIRLET7F2 MIRLET7G MIRLET7I
Entrez ID		1478	1479
HPRD ID		02652	02651
Ensembl ID		ENSG00000101811	ENSG00000176102
Uniprot IDs		B3V096 B4DUD5 E7EWR4 P33240	Q12996
PDB IDs		1P1T 2J8P 6Q2I 6TZE	6B3X 6URO 7ZY4
Enriched GO Terms of Interacting Partners?			RISC Complex MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Extracellular Vesicle Negative Regulation Of Gene Expression Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process MiRNA-mediated Gene Silencing By Inhibition Of Translation Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process Regulation Of Inflammatory Response Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Cardiac Muscle Cell Apoptotic Process Negative Regulation Of Cardiac Epithelial To Mesenchymal Transition Positive Regulation Of Cardiac Muscle Hypertrophy Negative Regulation Of Striated Muscle Cell Apoptotic Process Negative Regulation Of Defense Response MRNA 3'-UTR Binding Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Matrix Metallopeptidase Secretion Negative Regulation Of Cell Migration Regulation Of Muscle Cell Differentiation Regulation Of Cardiac Muscle Cell Apoptotic Process Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Cell Motility Positive Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Muscle Cell Apoptotic Process Negative Regulation Of Locomotion Negative Regulation Of Inflammatory Response Negative Regulation Of Translation Negative Regulation Of Cell Differentiation Regulation Of Extracellular Matrix Organization Negative Regulation Of Cellular Response To Transforming Growth Factor Beta Stimulus Negative Regulation Of Extracellular Matrix Assembly Negative Regulation Of Endothelial Cell Migration Regulation Of Matrix Metallopeptidase Secretion Cellular Response To Bacterial Lipopeptide Regulation Of Cardiac Muscle Hypertrophy HMG Box Domain Binding Negative Regulation Of Vascular Associated Smooth Muscle Cell Differentiation Response To Bacterial Lipoprotein Negative Regulation Of Fibroblast Migration Positive Regulation Of Muscle Cell Differentiation Regulation Of Defense Response
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?