PARP1 and APLF

  • Number of citations of the paper that reports this interaction (PMID 18172500)
  • 91
  • Data Source:
  • BioGRID (pull down, enzymatic study)

PARP1

APLF

Gene Name poly (ADP-ribose) polymerase 1 aprataxin and PNKP like factor
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 84 interactors: APLF APTX ATM BCL2 BUB3 CASP1 CASP3 CASP7 CASP8 CD86 CDKN1A CENPA CENPB CREBBP CTSB CTSG E2F1 ERCC6 ERG FOXO1 GTF2F1 GZMB GZMM H2AFY HDAC1 HDAC3 HIST1H1A HIST1H1C HIST1H2BA HIST1H4A HIST1H4C HIST2H2AA3 HMGA1 HOXB7 HSPA2 KAT2B LIG3 LZTR1 MED14 MED6 MYBL2 NCL NCOA6 NEDD8 NFATC1 NFKB1 NPM1 NRF1 PARP2 PARP3 PCNA PIAS4 POLA1 POLA2 POLB POU2F1 PRKDC RARA RBM14 RELA RNF146 RPS3A RXRA SENP1 SENP3 SIRT1 SP1 SREK1 SUMO1 SUMO2 SUPT16H SWAP70 TCF4 TP53 TRIM29 UBE2I UHRF1 WRN XRCC1 XRCC5 XRCC6 ZBTB16 ZBTB9 ZNF423 9 interactors: APP FBXO25 GMCL1 IRX5 LIG4 PARP1 XRCC1 XRCC4 XRCC5
Entrez ID 142 200558
HPRD ID 01435 09848
Ensembl ID ENSG00000143799 ENSG00000169621
Uniprot IDs P09874 Q8IW19
PDB IDs 1UK0 1UK1 1WOK 2COK 2CR9 2CS2 2DMJ 2JVN 2L30 2L31 2RCW 2RD6 2RIQ 3GJW 3GN7 3L3L 3L3M 3OD8 3ODA 3ODC 3ODE 4AV1 4DQY 4GV7 4HHY 4HHZ 4L6S 2KQB 2KQC 2KQD 2KQE 2KUO
Enriched GO Terms of Interacting Partners?
Tagcloud ?
ageing  ascribes  atm  attrition  brca1  complexity  ctip  ends  fusions  homologous  instability  insufficient  joining  ku70  lig3  lig4  mechanistically  nhej  overhang  rampant  relies  repeats  telomere  telomeres  telomeric  trf2  unanticipated  uncapped  underlining 
acidic  adp  analogs  ation  binds  chaperone  chaperones  chromatin  collectively  define  eukaryotes  exhibits  h4  histone  histones  homologous  localize  modulates  motif  nap1l  poly  poorly  preferentially  reactions  relaxation  repair  ribose  ribosyl  tetramer 
Tagcloud (Difference) ?
ageing  ascribes  atm  attrition  brca1  complexity  ctip  ends  fusions  instability  insufficient  joining  ku70  lig3  lig4  mechanistically  nhej  overhang  rampant  relies  repeats  telomere  telomeres  telomeric  trf2  unanticipated  uncapped  underlining 
acidic  adp  analogs  ation  binds  chaperone  chaperones  chromatin  collectively  define  eukaryotes  exhibits  h4  histone  histones  localize  modulates  motif  nap1l  poly  poorly  preferentially  reactions  relaxation  repair  ribose  ribosyl  tetramer 
Tagcloud (Intersection) ?
homologous