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OTUD6A and RBCK1
Number of citations of the paper that reports this interaction (PMID
23105109
)
4
Data Source:
BioGRID
(two hybrid)
OTUD6A
RBCK1
Gene Name
OTU deubiquitinase 6A
RanBP-type and C3HC4-type zinc finger containing 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
LUBAC Complex
Molecular Function
Ubiquitin-specific Protease Activity
Sequence-specific DNA Binding Transcription Factor Activity
Ubiquitin-protein Transferase Activity
Protein Binding
Zinc Ion Binding
Ligase Activity
Ubiquitin Binding
Biological Process
Proteolysis
Protein K29-linked Deubiquitination
Protein K11-linked Deubiquitination
Protein K27-linked Deubiquitination
Protein K33-linked Deubiquitination
Protein Polyubiquitination
Viral Process
Negative Regulation Of NF-kappaB Transcription Factor Activity
Positive Regulation Of NF-kappaB Import Into Nucleus
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
T Cell Receptor Signaling Pathway
Positive Regulation Of NF-kappaB Transcription Factor Activity
Negative Regulation Of Necroptotic Process
Protein Linear Polyubiquitination
Positive Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways
Antigen processing: Ubiquitination & Proteasome degradation
Class I MHC mediated antigen processing & presentation
Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions
7 interactors:
CBLC
RBCK1
RNF2
TRIM39
TRIM46
TRIM5
UBC
46 interactors:
APP
ARNT2
BACH1
CREBBP
IKBKG
IREB2
MKRN2
NAA10
NDUFAF3
NEDD4
NR1I2
OTUB2
OTUD6A
PAN2
PARK2
PCGF2
PRKCA
PSMD4
RNF181
RNF31
SOCS6
SYCE1
TNFAIP3
TRAF1
TRIM21
TRIM25
TRIM65
TRIML1
TSSK3
UBE2D3
UBE2D4
UBE2G1
UBE2K
UBE2L3
UBE2L6
UBE2N
UBE2S
UBE2U
UCHL5
UHRF2
USP15
USP2
USP21
USP32
USP49
USP7
Entrez ID
139562
10616
HPRD ID
13681
16643
Ensembl ID
ENSG00000189401
ENSG00000125826
Uniprot IDs
Q7L8S5
A6PVK0
Q9BYM8
PDB IDs
2CRC
2LGY
4DBG
Enriched GO Terms of Interacting Partners
?
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Positive Regulation Of NF-kappaB Transcription Factor Activity
Cellular Protein Modification Process
Protein Polyubiquitination
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Cellular Protein Metabolic Process
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Negative Regulation Of ERBB Signaling Pathway
Positive Regulation Of Signal Transduction
Regulation Of Signal Transduction
Immune Response-regulating Signaling Pathway
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Protein Metabolic Process
Regulation Of ERBB Signaling Pathway
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Regulation Of Signaling
Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Viral Process
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Negative Regulation Of Protein Ubiquitination
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
T Cell Receptor Signaling Pathway
Protein Catabolic Process
Positive Regulation Of Cell Death
Regulation Of MAPK Cascade
Positive Regulation Of Immune Response
Regulation Of Intracellular Signal Transduction
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
Histone H2A-K119 Monoubiquitination
Antigen Receptor-mediated Signaling Pathway
Activation Of Innate Immune Response
Protein Linear Polyubiquitination
Positive Regulation Of Intracellular Signal Transduction
Negative Regulation Of Cellular Protein Metabolic Process
Negative Regulation Of Cellular Metabolic Process
Cellular Macromolecule Catabolic Process
Positive Regulation Of Innate Immune Response
Regulation Of Immune Response
Negative Regulation Of Protein Metabolic Process
Positive Regulation Of Immune System Process
Regulation Of Metabolic Process
Positive Regulation Of Apoptotic Signaling Pathway
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Cellular Protein Modification Process
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Protein Catabolic Process
Protein Polyubiquitination
Ubiquitin-dependent Protein Catabolic Process
Cellular Protein Metabolic Process
Cellular Macromolecule Catabolic Process
Proteolysis
Proteasomal Protein Catabolic Process
Protein Metabolic Process
Protein Deubiquitination
Protein Modification By Small Protein Removal
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Catabolic Process
Cellular Metabolic Process
Regulation Of Protein Catabolic Process
Regulation Of Type I Interferon Production
Protein K63-linked Ubiquitination
Regulation Of Protein Metabolic Process
Regulation Of Cellular Protein Metabolic Process
Protein K48-linked Ubiquitination
Regulation Of Proteasomal Protein Catabolic Process
Response To Stress
Regulation Of Proteolysis
Histone Modification
Histone Deubiquitination
Cellular Response To Stress
Protein K29-linked Ubiquitination
Protein K27-linked Ubiquitination
Protein K11-linked Ubiquitination
Metabolic Process
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Innate Immune Response
Chromosome Organization
Protein K6-linked Ubiquitination
Protein K11-linked Deubiquitination
Negative Regulation Of Cellular Metabolic Process
Regulation Of Metabolic Process
Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
Regulation Of Nitrogen Compound Metabolic Process
Protein Monoubiquitination
Chromatin Modification
Protein Autoubiquitination
Negative Regulation Of Type I Interferon Production
Cellular Process
Regulation Of Transcription, DNA-templated
Tagcloud
?
1beta
ali
allocated
attenuates
autologous
c3hc4
dependently
dismutase
histology
intravenously
malondialdehyde
mda
oalt
occluded
orthotopic
oxidant
pathologic
peroxiredoxin
portal
prx
ranbp
restoring
sham
sod
started
u1
uh
ul
ulinastatin
Tagcloud (Difference)
?
1beta
ali
allocated
attenuates
autologous
c3hc4
dependently
dismutase
histology
intravenously
malondialdehyde
mda
oalt
occluded
orthotopic
oxidant
pathologic
peroxiredoxin
portal
prx
ranbp
restoring
sham
sod
started
u1
uh
ul
ulinastatin
Tagcloud (Intersection)
?