RBCK1 and MKRN2

Number of citations of the paper that reports this interaction (PMID 22493164)
2

Data Source:
BioGRID (two hybrid)

		RBCK1	MKRN2
Gene Name		RanBP-type and C3HC4-type zinc finger containing 1	makorin ring finger protein 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	LUBAC Complex	Intracellular
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ligase Activity Ubiquitin Binding	Protein Binding Zinc Ion Binding Ligase Activity Poly(A) RNA Binding
	Biological Process	Protein Polyubiquitination Viral Process Negative Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of NF-kappaB Import Into Nucleus Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process T Cell Receptor Signaling Pathway Positive Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Necroptotic Process Protein Linear Polyubiquitination Positive Regulation Of Extrinsic Apoptotic Signaling Pathway	Biological_process Protein Ubiquitination
Pathways		Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		46 interactors: APP ARNT2 BACH1 CREBBP IKBKG IREB2 MKRN2 NAA10 NDUFAF3 NEDD4 NR1I2 OTUB2 OTUD6A PAN2 PARK2 PCGF2 PRKCA PSMD4 RNF181 RNF31 SOCS6 SYCE1 TNFAIP3 TRAF1 TRIM21 TRIM25 TRIM65 TRIML1 TSSK3 UBE2D3 UBE2D4 UBE2G1 UBE2K UBE2L3 UBE2L6 UBE2N UBE2S UBE2U UCHL5 UHRF2 USP15 USP2 USP21 USP32 USP49 USP7	7 interactors: C1orf109 GNB2L1 NDN RBCK1 UBE2D1 UBE2D4 UBE2K
Entrez ID		10616	23609
HPRD ID		16643	09761
Ensembl ID		ENSG00000125826	ENSG00000075975
Uniprot IDs		A6PVK0 Q9BYM8	B4DPR4 Q9H000
PDB IDs		2CRC 2LGY 4DBG
Enriched GO Terms of Interacting Partners?		Protein Ubiquitination Protein Modification By Small Protein Conjugation Cellular Protein Modification Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Modification-dependent Protein Catabolic Process Protein Catabolic Process Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Cellular Protein Metabolic Process Cellular Macromolecule Catabolic Process Proteolysis Proteasomal Protein Catabolic Process Protein Metabolic Process Protein Deubiquitination Protein Modification By Small Protein Removal Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Catabolic Process Cellular Metabolic Process Regulation Of Protein Catabolic Process Regulation Of Type I Interferon Production Protein K63-linked Ubiquitination Regulation Of Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Protein K48-linked Ubiquitination Regulation Of Proteasomal Protein Catabolic Process Response To Stress Regulation Of Proteolysis Histone Modification Histone Deubiquitination Cellular Response To Stress Protein K29-linked Ubiquitination Protein K27-linked Ubiquitination Protein K11-linked Ubiquitination Metabolic Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Innate Immune Response Chromosome Organization Protein K6-linked Ubiquitination Protein K11-linked Deubiquitination Negative Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Regulation Of Nitrogen Compound Metabolic Process Protein Monoubiquitination Chromatin Modification Protein Autoubiquitination Negative Regulation Of Type I Interferon Production Cellular Process Regulation Of Transcription, DNA-templated	Protein Polyubiquitination Protein K48-linked Ubiquitination Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Protein Modification By Small Protein Conjugation Regulation Of Proteasomal Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Regulation Of Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process Regulation Of Proteolysis Positive Regulation Of CAMP Catabolic Process Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Positive Regulation Of Cellular Protein Catabolic Process Negative Regulation Of Hydrogen Peroxide-induced Neuron Death Protein Linear Polyubiquitination Cellular Macromolecule Catabolic Process Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Positive Regulation Of Apoptotic Signaling Pathway Protein K27-linked Ubiquitination Protein K29-linked Ubiquitination Positive Regulation Of Protein Catabolic Process Negative Regulation Of Oxidative Stress-induced Neuron Death Regulation Of Cell Division Protein K6-linked Ubiquitination Positive Regulation Of Proteolysis Positive Regulation Of Protein Homooligomerization Positive Regulation Of Gastrulation Negative Regulation Of Transferase Activity Negative Regulation Of Hydrogen Peroxide-induced Cell Death Positive Regulation Of Mitochondrial Depolarization Regulation Of Hydrogen Peroxide-induced Cell Death Negative Regulation Of Phagocytosis Protein Metabolic Process Negative Regulation Of Necroptotic Process Respiratory System Process Negative Regulation Of Necrotic Cell Death Cellular Protein Modification Process Regulation Of Necroptotic Process Negative Regulation Of Protein Tyrosine Kinase Activity Proteolysis Regulation Of Mitochondrial Depolarization Positive Regulation Of Protein Oligomerization Immune Response-regulating Signaling Pathway Positive Regulation Of NF-kappaB Import Into Nucleus Protein K11-linked Ubiquitination
Tagcloud ?		1beta ali allocated attenuates autologous c3hc4 dependently dismutase histology intravenously malondialdehyde mda oalt occluded orthotopic oxidant pathologic peroxiredoxin portal prx ranbp restoring sham sod started u1 uh ul ulinastatin
Tagcloud (Difference) ?		1beta ali allocated attenuates autologous c3hc4 dependently dismutase histology intravenously malondialdehyde mda oalt occluded orthotopic oxidant pathologic peroxiredoxin portal prx ranbp restoring sham sod started u1 uh ul ulinastatin
Tagcloud (Intersection) ?