RBCK1 and NAA10

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		RBCK1	NAA10
Gene Name		RanBP-type and C3HC4-type zinc finger containing 1	N(alpha)-acetyltransferase 10, NatA catalytic subunit
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	LUBAC Complex	Intracellular Nucleus Nucleolus Cytoplasm Membrane Cytosolic Ribosome NatA Complex
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ligase Activity Ubiquitin Binding	Peptide Alpha-N-acetyltransferase Activity Protein Binding N-acetyltransferase Activity Acetyltransferase Activity Ribosome Binding Peptide-serine-N-acetyltransferase Activity Peptide-glutamate-N-acetyltransferase Activity
	Biological Process	Protein Polyubiquitination Viral Process Negative Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of NF-kappaB Import Into Nucleus Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process T Cell Receptor Signaling Pathway Positive Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Necroptotic Process Protein Linear Polyubiquitination Positive Regulation Of Extrinsic Apoptotic Signaling Pathway	DNA Packaging N-terminal Protein Amino Acid Acetylation Internal Protein Amino Acid Acetylation N-terminal Peptidyl-serine Acetylation N-terminal Peptidyl-glutamic Acid Acetylation
Pathways		Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		46 interactors: APP ARNT2 BACH1 CREBBP IKBKG IREB2 MKRN2 NAA10 NDUFAF3 NEDD4 NR1I2 OTUB2 OTUD6A PAN2 PARK2 PCGF2 PRKCA PSMD4 RNF181 RNF31 SOCS6 SYCE1 TNFAIP3 TRAF1 TRIM21 TRIM25 TRIM65 TRIML1 TSSK3 UBE2D3 UBE2D4 UBE2G1 UBE2K UBE2L3 UBE2L6 UBE2N UBE2S UBE2U UCHL5 UHRF2 USP15 USP2 USP21 USP32 USP49 USP7	24 interactors: BCOR CALCOCO2 CDC25A CEP44 EHMT2 FIP1L1 HIF1A KIFAP3 KRTAP10-3 KRTAP10-5 KRTAP10-7 MEOX2 NAA15 NAA16 NAA50 NAT1 NAT2 PDE4DIP PSME2 RAB3IP RBCK1 RPL26 SSX2IP ZBTB14
Entrez ID		10616	8260
HPRD ID		16643	02056
Ensembl ID		ENSG00000125826
Uniprot IDs		A6PVK0 Q9BYM8	B4DKJ7 B7Z9N2 P41227
PDB IDs		2CRC 2LGY 4DBG
Enriched GO Terms of Interacting Partners?		Protein Ubiquitination Protein Modification By Small Protein Conjugation Cellular Protein Modification Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Modification-dependent Protein Catabolic Process Protein Catabolic Process Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Cellular Protein Metabolic Process Cellular Macromolecule Catabolic Process Proteolysis Proteasomal Protein Catabolic Process Protein Metabolic Process Protein Deubiquitination Protein Modification By Small Protein Removal Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Catabolic Process Cellular Metabolic Process Regulation Of Protein Catabolic Process Regulation Of Type I Interferon Production Protein K63-linked Ubiquitination Regulation Of Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Protein K48-linked Ubiquitination Regulation Of Proteasomal Protein Catabolic Process Response To Stress Regulation Of Proteolysis Histone Modification Histone Deubiquitination Cellular Response To Stress Protein K29-linked Ubiquitination Protein K27-linked Ubiquitination Protein K11-linked Ubiquitination Metabolic Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Innate Immune Response Chromosome Organization Protein K6-linked Ubiquitination Protein K11-linked Deubiquitination Negative Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Regulation Of Nitrogen Compound Metabolic Process Protein Monoubiquitination Chromatin Modification Protein Autoubiquitination Negative Regulation Of Type I Interferon Production Cellular Process Regulation Of Transcription, DNA-templated	N-terminal Protein Amino Acid Acetylation N-terminal Protein Amino Acid Modification Protein Acetylation Negative Regulation Of Programmed Cell Death Negative Regulation Of Cell Death Protein Stabilization Negative Regulation Of Apoptotic Process Regulation Of Apoptotic Process Negative Regulation Of Bone Mineralization Negative Regulation Of Biomineral Tissue Development Regulation Of Cell Death Microtubule-based Transport Regulation Of Protein Stability Cytoskeleton-dependent Intracellular Transport Cellular Protein Modification Process Neutral Amino Acid Transport Negative Regulation Of Histone H3-K36 Methylation Mitotic Sister Chromatid Cohesion, Centromeric Neural Fold Elevation Formation Positive Regulation Of Calcium-dependent Cell-cell Adhesion Viral Process Cellular Protein Metabolic Process Anatomical Structure Formation Involved In Morphogenesis Regulation Of Bone Mineralization Negative Regulation Of Tooth Mineralization Elastin Metabolic Process Protein Metabolic Process Negative Regulation Of Ossification Microtubule-based Movement Angiogenesis Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Positive Regulation Of Chemokine-mediated Signaling Pathway Vascular Endothelial Growth Factor Production Protein Linear Polyubiquitination Regulation Of Nitrogen Compound Metabolic Process Cellular Metabolic Process Connective Tissue Replacement Involved In Inflammatory Response Wound Healing Epithelial Cell Differentiation Involved In Mammary Gland Alveolus Development DNA Methylation On Cytosine Within A CG Sequence Intestinal Epithelial Cell Maturation Cellular Nitrogen Compound Metabolic Process Palate Development Positive Regulation Of Transcription, DNA-templated Histone Modification Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Specification Of Axis Polarity Norepinephrine Transport Amino Acid Transmembrane Transport Gene Expression Regulation Of Transcription, DNA-templated
Tagcloud ?		1beta ali allocated attenuates autologous c3hc4 dependently dismutase histology intravenously malondialdehyde mda oalt occluded orthotopic oxidant pathologic peroxiredoxin portal prx ranbp restoring sham sod started u1 uh ul ulinastatin	00e 19e 40e 47e asian autosomes cohorts contributors erythematosus gwas han intriguing irak1 l1cam mecp2 predisposition predominance prototype prototypic prps2 replicated replicating rs1059702 rs17422 rs2071128 rs7062536 sle tmem187 xp22
Tagcloud (Difference) ?		1beta ali allocated attenuates autologous c3hc4 dependently dismutase histology intravenously malondialdehyde mda oalt occluded orthotopic oxidant pathologic peroxiredoxin portal prx ranbp restoring sham sod started u1 uh ul ulinastatin	00e 19e 40e 47e asian autosomes cohorts contributors erythematosus gwas han intriguing irak1 l1cam mecp2 predisposition predominance prototype prototypic prps2 replicated replicating rs1059702 rs17422 rs2071128 rs7062536 sle tmem187 xp22
Tagcloud (Intersection) ?