CNTF and S100P

Number of citations of the paper that reports this interaction (PubMedID 34933172)
0

Data Source:
BioGRID (pull down)

		CNTF	S100P
Description		ciliary neurotrophic factor	S100 calcium binding protein P
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm Axon Neuronal Cell Body Glial Cell Projection	Extracellular Region Nucleus Nucleoplasm Cytoplasm Plasma Membrane Membrane Microvillus Membrane Secretory Granule Lumen Cell Projection Extracellular Exosome
	Molecular Function	Cytokine Activity Ciliary Neurotrophic Factor Receptor Binding Interleukin-6 Receptor Binding Protein Binding Growth Factor Activity Protein-containing Complex Binding	Magnesium Ion Binding Calcium Ion Binding Protein Binding Identical Protein Binding Protein Homodimerization Activity Cadherin Binding Metal Ion Binding Transition Metal Ion Binding Calcium-dependent Protein Binding
	Biological Process	Signal Transduction Cell Surface Receptor Signaling Pathway Via JAK-STAT Nervous System Development Positive Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Cell Differentiation Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Regulation Of Programmed Cell Death Negative Regulation Of Neuron Apoptotic Process Negative Regulation Of Photoreceptor Cell Differentiation Regulation Of Retinal Cell Programmed Cell Death Astrocyte Activation Muscle Organ Morphogenesis Neuron Development Positive Regulation Of Axon Regeneration Retinal Rod Cell Differentiation Ciliary Neurotrophic Factor-mediated Signaling Pathway Cell Surface Receptor Signaling Pathway Via STAT	Endothelial Cell Migration
Pathways		IL-6-type cytokine receptor ligand interactions	Neutrophil degranulation
Drugs			Cromoglicic acid
Diseases
GWAS		Diastolic blood pressure ( 27841878) Inflammatory bowel disease ( 23128233) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878) Ulcerative colitis ( 28067908)	Obesity-related traits ( 23251661)
Interacting Genes		16 interacting genes: AK8 APOE CNTFR CYSRT1 IL6R IL6ST KRT31 KRT40 LIFR NDUFAB1 RDM1 S100A1 S100A6 S100P TEPSIN TRIP6	46 interacting genes: AGER ARC CACYBP CEBPA CLCF1 CNTF CSF2 CSF3 CTF1 EBI3 EPO EZR GH1 GH2 IFNB1 IFNW1 IL10 IL11 IL12A IL13 IL15 IL20 IL21 IL22 IL24 IL26 IL27 IL3 IL31 IL5 IL9 LEP OSM PRL S100A1 S100A2 S100A4 S100B S100Z STUB1 SUGT1 TERF2IP TFIP11 TGFBI THPO UBL4A
Entrez ID		1270	6286
HPRD ID		00347	02792
Ensembl ID		ENSG00000242689	ENSG00000163993
Uniprot IDs		P26441	P25815
PDB IDs		1CNT 8D74	1J55 1OZO 2MJW 7NMI
Enriched GO Terms of Interacting Partners?		Ciliary Neurotrophic Factor Receptor Activity Ciliary Neurotrophic Factor-mediated Signaling Pathway Ciliary Neurotrophic Factor Receptor Complex Interleukin-11 Receptor Activity Interleukin-11 Binding Interleukin-11-mediated Signaling Pathway Cytokine Receptor Activity Interleukin-6 Binding Interleukin-6 Receptor Activity Leukemia Inhibitory Factor Receptor Activity Interleukin-6 Receptor Complex Oncostatin-M Receptor Activity Leukemia Inhibitory Factor Signaling Pathway Oncostatin-M-mediated Signaling Pathway Cytokine Binding Ciliary Neurotrophic Factor Receptor Binding Regulation Of Platelet Activation Interleukin-6 Receptor Binding Structural Molecule Activity Protein Homodimerization Activity Positive Regulation Of Platelet Aggregation Calcium-dependent Protein Binding T-helper 17 Cell Lineage Commitment S100 Protein Binding Interleukin-6-mediated Signaling Pathway T-helper Cell Lineage Commitment Positive Regulation Of Homotypic Cell-cell Adhesion CD4-positive, Alpha-beta T Cell Lineage Commitment Alpha-beta T Cell Lineage Commitment CD4-positive Or CD8-positive, Alpha-beta T Cell Lineage Commitment External Side Of Plasma Membrane Regulation Of Platelet Aggregation T Cell Lineage Commitment Cytokine-mediated Signaling Pathway Negative Regulation Of Phospholipid Efflux Negative Regulation Of Postsynaptic Membrane Organization Positive Regulation Of Lipid Transport Across Blood-brain Barrier Negative Regulation Of Lipid Transport Across Blood-brain Barrier Regulation Of Cellular Response To Very-low-density Lipoprotein Particle Stimulus Metal Chelating Activity Intermediate-density Lipoprotein Particle Clearance Receptor Complex Ciliary Neurotrophic Factor Binding Growth Factor Binding Acyl Carrier Activity Coated Vesicle Membrane Vasodilation Structural Constituent Of Skin Epidermis Positive Regulation Of Cell Population Proliferation Positive Regulation Of Presynaptic Membrane Organization	Cytokine Activity Extracellular Space Cytokine-mediated Signaling Pathway Extracellular Region Growth Factor Activity Positive Regulation Of Cell Population Proliferation Regulation Of Cell Population Proliferation Signal Transduction Cell Surface Receptor Signaling Pathway Via STAT Regulation Of Leukocyte Proliferation Regulation Of Mononuclear Cell Proliferation Cytokine Receptor Binding Cell Surface Receptor Signaling Pathway Positive Regulation Of Leukocyte Proliferation Positive Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Lymphocyte Proliferation Positive Regulation Of Mononuclear Cell Proliferation Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Multicellular Organismal Process Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT Regulation Of Multicellular Organismal Process Regulation Of Receptor Signaling Pathway Via JAK-STAT Leukocyte Differentiation Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Receptor Signaling Pathway Via STAT Regulation Of Tyrosine Phosphorylation Of STAT Protein Regulation Of Lymphocyte Activation Positive Regulation Of Developmental Process Regulation Of Cell Activation Immune System Process Cell Activation Positive Regulation Of Metabolic Process Leukocyte Activation S100 Protein Binding Positive Regulation Of Protein Modification Process Positive Regulation Of Cell Activation Cell Surface Receptor Signaling Pathway Via JAK-STAT Positive Regulation Of Protein Phosphorylation Positive Regulation Of Cytokine Production Immune Response Positive Regulation Of Phosphorylation Positive Regulation Of Gene Expression Positive Regulation Of Lymphocyte Activation Regulation Of T Cell Proliferation Positive Regulation Of Protein Metabolic Process Regulation Of Cytokine Production Regulation Of Developmental Process Regulation Of Protein Phosphorylation Regulation Of T Cell Activation
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?