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AEBP2 and HIST1H1A
Number of citations of the paper that reports this interaction (PMID
16431907
)
16
Data Source:
BioGRID
(pull down)
AEBP2
HIST1H1A
Gene Name
AE binding protein 2
histone cluster 1, H1a
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleoplasm
ESC/E(Z) Complex
Nucleosome
Nuclear Chromatin
Nuclear Euchromatin
Molecular Function
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription
Transcription Corepressor Activity
Metal Ion Binding
Protein Binding
Chromatin DNA Binding
Biological Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Transcription, DNA-templated
Gene Expression
Chromatin Modification
Regulation Of Gene Expression, Epigenetic
Negative Regulation Of Gene Expression, Epigenetic
Nucleosome Assembly
Spermatogenesis
Pathways
Epigenetic regulation of gene expression
PRC2 methylates histones and DNA
DNA Damage/Telomere Stress Induced Senescence
Formation of Senescence-Associated Heterochromatin Foci (SAHF)
Activation of DNA fragmentation factor
Apoptosis induced DNA fragmentation
Cellular Senescence
Programmed Cell Death
Apoptotic execution phase
Drugs
Diseases
GWAS
Obesity-related traits (
23251661
)
Pulmonary function (
21946350
)
Protein-Protein Interactions
10 interactors:
APP
EED
HIST1H1A
HIST1H1C
HMBOX1
JMJD6
LDOC1
RALYL
RBBP4
SUZ12
45 interactors:
AEBP2
CCNA1
CCNA2
CCNB1
CCND2
CCNE1
CDK1
CDK2
CDK4
CDK6
CDK7
CDKN1B
CRP
CTCFL
EED
EHMT2
EP300
EZH2
GADD45A
GZMA
IRAK4
KAT2B
LIMK1
LIMK2
LOX
NAP1L4
NASP
PARP1
PARP3
PELP1
PKN1
PRDM1
PRKCA
PRKCB
PRKCD
PRKCE
PRKCZ
PRKDC
PTMA
RBBP4
SUZ12
TERF1
TERF2IP
TLK1
WHSC1L1
Entrez ID
121536
3024
HPRD ID
16477
00820
Ensembl ID
ENSG00000124610
Uniprot IDs
Q6ZN18
Q02539
PDB IDs
Enriched GO Terms of Interacting Partners
?
Chromatin Organization
Chromosome Organization
Negative Regulation Of Gene Expression, Epigenetic
Nucleosome Assembly
Chromatin Assembly
Nucleosome Organization
Chromatin Assembly Or Disassembly
Protein-DNA Complex Assembly
DNA Packaging
Chromatin Modification
Regulation Of Gene Expression, Epigenetic
DNA Conformation Change
Organelle Organization
Histone Modification
RNA Metabolic Process
Histone H3-R2 Demethylation
Histone H4-R3 Demethylation
Peptidyl-lysine Hydroxylation To 5-hydroxy-L-lysine
Gene Expression
Synaptic Growth At Neuromuscular Junction
Transcription, DNA-templated
RNA Biosynthetic Process
Histone Methylation
Negative Regulation Of Gene Expression
Cell Recognition
Collateral Sprouting In Absence Of Injury
Cellular Macromolecular Complex Assembly
Regulation Of Transcription, DNA-templated
Collateral Sprouting
Axon Midline Choice Point Recognition
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Protein Methylation
Regulation Of RNA Metabolic Process
Smooth Endoplasmic Reticulum Calcium Ion Homeostasis
Nucleobase-containing Compound Metabolic Process
Nucleosome Positioning
Axon Choice Point Recognition
Recognition Of Apoptotic Cell
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Neuron Remodeling
DNA Replication-dependent Nucleosome Assembly
Regulation Of Gene Expression
Cellular Component Assembly
Regulation Of Nitrogen Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Positive Regulation Of Histone H3-K27 Methylation
Regulation Of Histone H3-K27 Methylation
Negative Regulation Of Cellular Metabolic Process
Chromosome Organization
Cell Cycle
Chromatin Organization
Chromatin Modification
Regulation Of Cell Cycle
Organelle Organization
Cell Cycle Process
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
Cellular Protein Modification Process
Regulation Of Cellular Protein Metabolic Process
Histone Modification
Regulation Of Metabolic Process
Mitotic Cell Cycle Process
Regulation Of Protein Metabolic Process
Regulation Of Protein Kinase Activity
Regulation Of Protein Phosphorylation
Mitotic Cell Cycle
Positive Regulation Of Cellular Metabolic Process
Regulation Of Kinase Activity
Regulation Of Phosphorylation
Regulation Of Nitrogen Compound Metabolic Process
Cellular Protein Metabolic Process
G2/M Transition Of Mitotic Cell Cycle
Positive Regulation Of Metabolic Process
Regulation Of Phosphorus Metabolic Process
Protein Phosphorylation
Regulation Of Mitotic Cell Cycle
Protein Metabolic Process
G1/S Transition Of Mitotic Cell Cycle
Cell Division
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Regulation Of Gene Expression
Negative Regulation Of Cellular Metabolic Process
Negative Regulation Of Cell Cycle
DNA Metabolic Process
Cellular Response To Stress
Response To Stress
Histone Phosphorylation
Regulation Of Catalytic Activity
Peptidyl-amino Acid Modification
Cellular Metabolic Process
Regulation Of Cell Cycle Process
Phosphorylation
Nucleobase-containing Compound Metabolic Process
Positive Regulation Of Cell Cycle
Regulation Of Cellular Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of Gene Expression, Epigenetic
Tagcloud
?
chromatin
complexes
components
constitute
creates
domains
establishing
feedback
form
h2a
h2aub
h3k27
h3k27me3
histone
jarid2
k27
key
loop
monoubiquitination
nucleosomes
pcr2
polycomb
prc1
prc2
promotes
provides
repression
step
trimethylation
Tagcloud (Difference)
?
chromatin
complexes
components
constitute
creates
domains
establishing
feedback
form
h2a
h2aub
h3k27
h3k27me3
histone
jarid2
k27
key
loop
monoubiquitination
nucleosomes
pcr2
polycomb
prc1
prc2
promotes
provides
repression
step
trimethylation
Tagcloud (Intersection)
?