AEBP2 and RALYL

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
HPRD (two hybrid)

		AEBP2	RALYL
Gene Name		AE binding protein 2	RALY RNA binding protein-like
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm ESC/E(Z) Complex
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription Transcription Corepressor Activity Metal Ion Binding	Nucleotide Binding Poly(A) RNA Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Gene Expression Chromatin Modification Regulation Of Gene Expression, Epigenetic Negative Regulation Of Gene Expression, Epigenetic
Pathways		Epigenetic regulation of gene expression PRC2 methylates histones and DNA
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661) Pulmonary function ( 21946350)
Protein-Protein Interactions		10 interactors: APP EED HIST1H1A HIST1H1C HMBOX1 JMJD6 LDOC1 RALYL RBBP4 SUZ12	17 interactors: AEBP2 AEN BYSL C20orf27 CCDC85B CEP170P1 EWSR1 FXR2 HNRNPC LMO3 LRRK2 MCRS1 PSMF1 RBM41 THAP1 TSNAX ZNF408
Entrez ID		121536	138046
HPRD ID		16477	11236
Ensembl ID			ENSG00000184672
Uniprot IDs		Q6ZN18	B3KSX3 B3KT61 G3V129 Q86SE5
PDB IDs
Enriched GO Terms of Interacting Partners?		Chromatin Organization Chromosome Organization Negative Regulation Of Gene Expression, Epigenetic Nucleosome Assembly Chromatin Assembly Nucleosome Organization Chromatin Assembly Or Disassembly Protein-DNA Complex Assembly DNA Packaging Chromatin Modification Regulation Of Gene Expression, Epigenetic DNA Conformation Change Organelle Organization Histone Modification RNA Metabolic Process Histone H3-R2 Demethylation Histone H4-R3 Demethylation Peptidyl-lysine Hydroxylation To 5-hydroxy-L-lysine Gene Expression Synaptic Growth At Neuromuscular Junction Transcription, DNA-templated RNA Biosynthetic Process Histone Methylation Negative Regulation Of Gene Expression Cell Recognition Collateral Sprouting In Absence Of Injury Cellular Macromolecular Complex Assembly Regulation Of Transcription, DNA-templated Collateral Sprouting Axon Midline Choice Point Recognition Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Protein Methylation Regulation Of RNA Metabolic Process Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Nucleobase-containing Compound Metabolic Process Nucleosome Positioning Axon Choice Point Recognition Recognition Of Apoptotic Cell Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Neuron Remodeling DNA Replication-dependent Nucleosome Assembly Regulation Of Gene Expression Cellular Component Assembly Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Histone H3-K27 Methylation Regulation Of Histone H3-K27 Methylation Negative Regulation Of Cellular Metabolic Process	Cellular Nitrogen Compound Metabolic Process RNA Metabolic Process Nitrogen Compound Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Cellular Metabolic Process Negative Regulation Of Protein Processing Involved In Protein Targeting To Mitochondrion Negative Regulation Of Protein Targeting To Mitochondrion Positive Regulation Of Glucocorticoid Receptor Signaling Pathway Negative Regulation Of Thioredoxin Peroxidase Activity By Peptidyl-threonine Phosphorylation Negative Regulation Of Peroxidase Activity Regulation Of Gene Expression Regulation Of Metabolic Process Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Protein Autoubiquitination Negative Regulation Of Late Endosome To Lysosome Transport Regulation Of Protein Autoubiquitination Positive Regulation Of Dopamine Receptor Signaling Pathway Cellular Response To Dopamine Signal Transduction By P53 Class Mediator Regulation Of Protein Targeting To Mitochondrion Regulation Of Branching Morphogenesis Of A Nerve Regulation Of Kidney Size Regulation Of Fat Cell Differentiation Cellular Response To Manganese Ion Positive Regulation Of Protein Ubiquitination Cellular Macromolecule Biosynthetic Process Intracellular Distribution Of Mitochondria Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Macromolecule Biosynthetic Process Positive Regulation Of Cellular Protein Catabolic Process Regulation Of Dopamine Receptor Signaling Pathway Regulation Of Neuron Maturation Tangential Migration From The Subventricular Zone To The Olfactory Bulb Regulation Of Nitrogen Compound Metabolic Process Chromatin Modification Positive Regulation Of Peroxisome Proliferator Activated Receptor Signaling Pathway 3'-UTR-mediated MRNA Stabilization Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Protein Ubiquitination Negative Regulation Of Hydrogen Peroxide-induced Cell Death Locomotory Exploration Behavior Regulation Of Mitochondrial Fission Positive Regulation Of Protein Catabolic Process Histone H4-K5 Acetylation
Tagcloud ?		chromatin complexes components constitute creates domains establishing feedback form h2a h2aub h3k27 h3k27me3 histone jarid2 k27 key loop monoubiquitination nucleosomes pcr2 polycomb prc1 prc2 promotes provides repression step trimethylation
Tagcloud (Difference) ?		chromatin complexes components constitute creates domains establishing feedback form h2a h2aub h3k27 h3k27me3 histone jarid2 k27 key loop monoubiquitination nucleosomes pcr2 polycomb prc1 prc2 promotes provides repression step trimethylation
Tagcloud (Intersection) ?