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AEBP2
Gene Name
AE binding protein 2
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleoplasm
ESC/E(Z) Complex
Molecular Function
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription
Transcription Corepressor Activity
Metal Ion Binding
Biological Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Transcription, DNA-templated
Gene Expression
Chromatin Modification
Regulation Of Gene Expression, Epigenetic
Negative Regulation Of Gene Expression, Epigenetic
Pathways
Epigenetic regulation of gene expression
PRC2 methylates histones and DNA
Drugs
Diseases
GWAS
Obesity-related traits (
23251661
)
Pulmonary function (
21946350
)
Protein-protein Interactions
10 interactors:
APP
EED
HIST1H1A
HIST1H1C
HMBOX1
JMJD6
LDOC1
RALYL
RBBP4
SUZ12
Entrez ID
121536
HPRD ID
16477
Ensembl ID
Uniprot IDs
Q6ZN18
PDB IDs
Enriched GO Terms of Interacting Partners
?
Chromatin Organization
Chromosome Organization
Negative Regulation Of Gene Expression, Epigenetic
Nucleosome Assembly
Chromatin Assembly
Nucleosome Organization
Chromatin Assembly Or Disassembly
Protein-DNA Complex Assembly
DNA Packaging
Chromatin Modification
Regulation Of Gene Expression, Epigenetic
DNA Conformation Change
Organelle Organization
Histone Modification
RNA Metabolic Process
Histone H3-R2 Demethylation
Histone H4-R3 Demethylation
Peptidyl-lysine Hydroxylation To 5-hydroxy-L-lysine
Gene Expression
Synaptic Growth At Neuromuscular Junction
Transcription, DNA-templated
RNA Biosynthetic Process
Histone Methylation
Negative Regulation Of Gene Expression
Cell Recognition
Collateral Sprouting In Absence Of Injury
Cellular Macromolecular Complex Assembly
Regulation Of Transcription, DNA-templated
Collateral Sprouting
Axon Midline Choice Point Recognition
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Protein Methylation
Regulation Of RNA Metabolic Process
Smooth Endoplasmic Reticulum Calcium Ion Homeostasis
Nucleobase-containing Compound Metabolic Process
Nucleosome Positioning
Axon Choice Point Recognition
Recognition Of Apoptotic Cell
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Neuron Remodeling
DNA Replication-dependent Nucleosome Assembly
Regulation Of Gene Expression
Cellular Component Assembly
Regulation Of Nitrogen Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Positive Regulation Of Histone H3-K27 Methylation
Regulation Of Histone H3-K27 Methylation
Negative Regulation Of Cellular Metabolic Process
Tagcloud
?
chromatin
complexes
components
constitute
creates
domains
establishing
feedback
form
h2a
h2aub
h3k27
h3k27me3
histone
jarid2
k27
key
loop
monoubiquitination
nucleosomes
pcr2
polycomb
prc1
prc2
promotes
provides
repression
step
trimethylation