CPSF7 and SNRNP25

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		CPSF7	SNRNP25
Gene Name		cleavage and polyadenylation specific factor 7, 59kDa	small nuclear ribonucleoprotein 25kDa (U11/U12)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm MRNA Cleavage Factor Complex Membrane	Nucleus Nucleoplasm U12-type Spliceosomal Complex Cytoplasm Intercellular Bridge
	Molecular Function	Nucleotide Binding Protein Binding Poly(A) RNA Binding
	Biological Process	MRNA Splicing, Via Spliceosome Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription RNA Splicing Gene Expression MRNA 3'-end Processing Protein Tetramerization	MRNA Processing RNA Splicing
Pathways		mRNA Splicing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Processing of Capped Intronless Pre-mRNA mRNA Splicing - Major Pathway Cleavage of Growing Transcript in the Termination Region RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs mRNA 3'-end processing
Drugs
Diseases
GWAS
Protein-Protein Interactions		22 interactors: AES APBB1 ARMC7 ATXN1 CLK2 CSNK2A1 DVL2 EPM2AIP1 EWSR1 GCC1 ITCH NCK2 NUDT21 PRMT2 RUNX1T1 SEC23B SMAD3 SNRNP25 SORBS3 U2AF2 WBP4 WWOX	9 interactors: C11orf57 CPSF7 EFHC2 KRT31 LHX4 LNX1 REL TRAF2 UBC
Entrez ID		79869	79622
HPRD ID		16906	12673
Ensembl ID		ENSG00000149532
Uniprot IDs		B4DGF8 Q8N684	Q9BV90
PDB IDs		3N9U
Enriched GO Terms of Interacting Partners?		Regulation Of RNA Metabolic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process RNA Metabolic Process Regulation Of Wnt Signaling Pathway Positive Regulation Of Metabolic Process Gene Expression RNA Processing Transcription, DNA-templated Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process RNA Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Gene Expression Regulation Of Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Regulation Of Signal Transduction Negative Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Wnt Signaling Pathway Regulation Of Signaling Nucleobase-containing Compound Metabolic Process Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Regulation Of Growth Positive Regulation Of Cell Death Regulation Of Apoptotic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Cell Growth RNA Splicing Regulation Of Cell Death Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Signal Transduction Negative Regulation Of Nucleic Acid-templated Transcription Cellular Nitrogen Compound Metabolic Process Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Wnt Signaling Pathway Negative Regulation Of Phosphorylation Negative Regulation Of Signaling Cellular Macromolecule Biosynthetic Process MRNA Processing Macromolecule Biosynthetic Process Positive Regulation Of Signal Transduction Negative Regulation Of Cell Cycle Termination Of RNA Polymerase II Transcription	I-kappaB Kinase/NF-kappaB Signaling NIK/NF-kappaB Signaling Negative Regulation Of Cell Death Positive Regulation Of Cytokine Production TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Protein Oligomerization Toll-like Receptor 4 Signaling Pathway Regulation Of Cytokine Production Toll-like Receptor Signaling Pathway Protein Ubiquitination Regulation Of Cell Death Protein Modification By Small Protein Conjugation Positive Regulation Of NF-kappaB Transcription Factor Activity Protein Catabolic Process Medial Motor Column Neuron Differentiation Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Response To Cytokine Protein Polyubiquitination Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Intracellular Signal Transduction Innate Immune Response Positive Regulation Of Innate Immune Response Transcription From RNA Polymerase II Promoter Negative Regulation Of Neuron Death Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of MAP Kinase Activity Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Glial Cell Apoptotic Process Protein Processing Somatic Motor Neuron Differentiation Regulation Of Innate Immune Response Protein Homooligomerization Transcription, DNA-templated Protein Complex Assembly Activation Of Protein Kinase Activity Positive Regulation Of Protein Serine/threonine Kinase Activity RNA Biosynthetic Process Positive Regulation Of Protein Homodimerization Activity Regulation Of Neuron Death Regulation Of MAP Kinase Activity Positive Regulation Of Proteolysis Viral Protein Processing Cellular Response To Nitric Oxide Positive Regulation Of Interleukin-12 Biosynthetic Process
Tagcloud ?			12q alk backgroundthe ccnd3 conclusionsour ews fli1 foxo1 fusion fusions harbor inactivating kcnmb4 lrp1 methodstranscriptome opportunities osteosarcoma osteosarcomas pax3 resultsnine sanger saos sarcomas ssx1 ssx2 syt tpm3 tpm4 transcriptome
Tagcloud (Difference) ?			12q alk backgroundthe ccnd3 conclusionsour ews fli1 foxo1 fusion fusions harbor inactivating kcnmb4 lrp1 methodstranscriptome opportunities osteosarcoma osteosarcomas pax3 resultsnine sanger saos sarcomas ssx1 ssx2 syt tpm3 tpm4 transcriptome
Tagcloud (Intersection) ?