PNMA5 and AP1M1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		PNMA5	AP1M1
Gene Name		paraneoplastic Ma antigen family member 5	adaptor-related protein complex 1, mu 1 subunit
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component		Golgi Membrane Lysosomal Membrane Cytosol Membrane Clathrin Adaptor Complex Cytoplasmic Vesicle Membrane Clathrin-coated Vesicle Membrane Trans-Golgi Network Membrane Extracellular Vesicular Exosome
	Molecular Function		Protein Binding
	Biological Process	Positive Regulation Of Apoptotic Process	Intracellular Protein Transport Post-Golgi Vesicle-mediated Transport Viral Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Melanosome Organization Endosome To Melanosome Transport Regulation Of Defense Response To Virus By Virus Membrane Organization
Pathways			Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters HIV Infection Host Interactions of HIV factors Golgi Associated Vesicle Biogenesis The role of Nef in HIV-1 replication and disease pathogenesis Nef mediated downregulation of MHC class I complex cell surface expression Clathrin derived vesicle budding Lysosome Vesicle Biogenesis MHC class II antigen presentation trans-Golgi Network Vesicle Budding Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		32 interactors: AP1M1 ARPC4 C11orf49 CARD9 CCDC102B CCNC CDC23 CEP57L1 CETN2 DDX6 GLIPR2 GORASP2 GRB2 KPNA2 MOAP1 MYO15B PNMA1 POLR3C PRKAA1 PSMA1 RAD23B SH3KBP1 TBC1D22B TNPO2 TTC23 TXNL4B VIM VPS28 WDYHV1 ZBTB25 ZFYVE26 ZMYND19	43 interactors: AP1B1 AP1M2 AP2B1 BRCA1 CEP57L1 CORO7 CTLA4 DCX DVL2 DZIP3 EHD2 ETV6 FAM9B FXR2 GAK GRIN2A GRIN2B HNRNPC HOOK2 IKZF1 KIF13A KRT40 KRTAP10-3 KRTAP10-7 LAMP1 LDOC1 LZTS2 MTF1 PHC2 PIGR PNMA5 RUNDC3A SDCCAG3 SELP SSX2IP TGOLN2 TIFA TNIP1 VAMP4 ZBTB14 ZBTB43 ZBTB44 ZBTB8A
Entrez ID		114824	8907
HPRD ID		06678	04639
Ensembl ID		ENSG00000198883	ENSG00000072958
Uniprot IDs		Q96PV4	B3KNH5 E7ENJ6 Q59EK3 Q9BXS5
PDB IDs
Enriched GO Terms of Interacting Partners?		Organelle Organization Viral Process Negative Regulation Of Protein Ubiquitination Cellular Response To DNA Damage Stimulus Enzyme Linked Receptor Protein Signaling Pathway Cell Cycle Response To Stress Cell Cycle Process Negative Regulation Of Glucosylceramide Biosynthetic Process Cold Acclimation Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Cellular Response To Stress Negative Regulation Of ERBB Signaling Pathway Mitotic Cell Cycle Regulation Of Protein Ubiquitination Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Nucleotide-excision Repair, DNA Damage Recognition Ubiquitin-dependent Protein Catabolic Process Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Ubiquitin-protein Transferase Activity Modification-dependent Protein Catabolic Process Cellular Macromolecule Catabolic Process Positive Regulation Of Signal Transduction Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Proteolysis Involved In Cellular Protein Catabolic Process Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Protein Targeting To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Negative Regulation Of Glucose Import In Response To Insulin Stimulus Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Cellular Protein Localization Positive Regulation Of Ligase Activity Regulation Of Cell Cycle Cellular Protein Catabolic Process Regulation Of ERBB Signaling Pathway Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Response To Camptothecin Protein Insertion Into Mitochondrial Membrane Regulation Of Ubiquitin-protein Transferase Activity Protein Catabolic Process Regulation Of MAPK Cascade Regulation Of Cellular Component Organization Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Signal Transduction In Response To DNA Damage Nucleotide-excision Repair	Vesicle-mediated Transport Cellular Localization Post-Golgi Vesicle-mediated Transport Establishment Of Localization In Cell Regulation Of Defense Response To Virus By Virus Intracellular Transport Endosomal Transport Protein Localization Lysosomal Transport Golgi Vesicle Transport Regulation Of Immune System Process Cellular Protein Localization Vacuolar Transport Regulation Of Defense Response To Virus Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Microtubule Cytoskeleton Organization Endomembrane System Organization Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Transport Regulation Of Cellular Process Startle Response Microtubule-based Process Endosome To Lysosome Transport Positive Regulation Of Cell Activation Cytoskeleton Organization Clathrin-mediated Endocytosis Establishment Of Protein Localization Positive Regulation Of Neutrophil Differentiation Positive Regulation Of Histone H4-K20 Methylation Modulation By Symbiont Of Host I-kappaB Kinase/NF-kappaB Cascade Positive Regulation Of Histone H4-K16 Acetylation Membrane Organization Cellular Protein Complex Assembly Organelle Organization Synaptic Transmission, Glutamatergic Ionotropic Glutamate Receptor Signaling Pathway Positive Regulation Of Histone H3-K9 Acetylation Intrahepatic Bile Duct Development Positive Regulation Of Natural Killer Cell Degranulation Selenium Compound Metabolic Process Cytoplasmic Transport Glutamate Receptor Signaling Pathway Convergent Extension Involved In Neural Plate Elongation Immunoglobulin Transcytosis In Epithelial Cells Mediated By Polymeric Immunoglobulin Receptor Regulation Of Organelle Transport Along Microtubule Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation Golgi To Lysosome Transport Neuron-neuron Synaptic Transmission
Tagcloud ?			19p13 adaptor ap1m2 ap2m1 chromosome clathrin cloned closely distantly diverged duplication except exclusively fact genomic homolog identical insertion intron introns mapped mu1a mu1b mu2 positions proximal separation similarity syntenic
Tagcloud (Difference) ?			19p13 adaptor ap1m2 ap2m1 chromosome clathrin cloned closely distantly diverged duplication except exclusively fact genomic homolog identical insertion intron introns mapped mu1a mu1b mu2 positions proximal separation similarity syntenic
Tagcloud (Intersection) ?