PNMA5 and ARPC4

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		PNMA5	ARPC4
Gene Name		paraneoplastic Ma antigen family member 5	actin related protein 2/3 complex, subunit 4, 20kDa
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component		Cytosol Arp2/3 Protein Complex Cell Projection Extracellular Vesicular Exosome
	Molecular Function		Structural Constituent Of Cytoskeleton Protein Binding Enzyme Binding Protein Binding, Bridging Actin Filament Binding
	Biological Process	Positive Regulation Of Apoptotic Process	Axon Guidance Actin Filament Polymerization Arp2/3 Complex-mediated Actin Nucleation Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Actin Nucleation Innate Immune Response Ephrin Receptor Signaling Pathway
Pathways			EPHB-mediated forward signaling Axon guidance EPH-Ephrin signaling Fcgamma receptor (FCGR) dependent phagocytosis Regulation of actin dynamics for phagocytic cup formation Innate Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		32 interactors: AP1M1 ARPC4 C11orf49 CARD9 CCDC102B CCNC CDC23 CEP57L1 CETN2 DDX6 GLIPR2 GORASP2 GRB2 KPNA2 MOAP1 MYO15B PNMA1 POLR3C PRKAA1 PSMA1 RAD23B SH3KBP1 TBC1D22B TNPO2 TTC23 TXNL4B VIM VPS28 WDYHV1 ZBTB25 ZFYVE26 ZMYND19	10 interactors: ACTR2 ACTR3 ARPC1B ARPC2 ARPC3 ARPC5 ARPC5L NELFCD PNMA5 RNF130
Entrez ID		114824	10093
HPRD ID		06678	10368
Ensembl ID		ENSG00000198883	ENSG00000241553
Uniprot IDs		Q96PV4	P59998
PDB IDs
Enriched GO Terms of Interacting Partners?		Organelle Organization Viral Process Negative Regulation Of Protein Ubiquitination Cellular Response To DNA Damage Stimulus Enzyme Linked Receptor Protein Signaling Pathway Cell Cycle Response To Stress Cell Cycle Process Negative Regulation Of Glucosylceramide Biosynthetic Process Cold Acclimation Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Cellular Response To Stress Negative Regulation Of ERBB Signaling Pathway Mitotic Cell Cycle Regulation Of Protein Ubiquitination Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Nucleotide-excision Repair, DNA Damage Recognition Ubiquitin-dependent Protein Catabolic Process Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Ubiquitin-protein Transferase Activity Modification-dependent Protein Catabolic Process Cellular Macromolecule Catabolic Process Positive Regulation Of Signal Transduction Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Proteolysis Involved In Cellular Protein Catabolic Process Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Protein Targeting To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Negative Regulation Of Glucose Import In Response To Insulin Stimulus Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Cellular Protein Localization Positive Regulation Of Ligase Activity Regulation Of Cell Cycle Cellular Protein Catabolic Process Regulation Of ERBB Signaling Pathway Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Response To Camptothecin Protein Insertion Into Mitochondrial Membrane Regulation Of Ubiquitin-protein Transferase Activity Protein Catabolic Process Regulation Of MAPK Cascade Regulation Of Cellular Component Organization Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Signal Transduction In Response To DNA Damage Nucleotide-excision Repair	Arp2/3 Complex-mediated Actin Nucleation Actin Nucleation Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Protein Polymerization Positive Regulation Of Protein Complex Assembly Regulation Of Actin Filament Polymerization Positive Regulation Of Cytoskeleton Organization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Actin Filament Organization Positive Regulation Of Cellular Component Biogenesis Regulation Of Cellular Component Size Regulation Of Protein Complex Assembly Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Organelle Organization Regulation Of Actin Filament-based Process Regulation Of Cytoskeleton Organization Ephrin Receptor Signaling Pathway Actin Cytoskeleton Organization Actin Filament-based Process Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Regulation Of Organelle Organization Phagocytosis Fc Receptor Signaling Pathway Cytoskeleton Organization Immune Response-activating Cell Surface Receptor Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Axon Guidance Meiotic Chromosome Movement Towards Spindle Pole Immune Response-regulating Signaling Pathway Axonogenesis Axon Development Asymmetric Cell Division Cell Morphogenesis Involved In Neuron Differentiation Regulation Of Cellular Component Organization Chemotaxis Positive Regulation Of Immune Response Neuron Projection Morphogenesis Endocytosis Meiotic Cytokinesis Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Morphogenesis Involved In Differentiation Innate Immune Response Movement Of Cell Or Subcellular Component Neuron Projection Development Cell Projection Morphogenesis Cell Part Morphogenesis Regulation Of Immune Response
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