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PNMA5 and DDX6
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
PNMA5
DDX6
Gene Name
paraneoplastic Ma antigen family member 5
DEAD (Asp-Glu-Ala-Asp) box helicase 6
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasmic MRNA Processing Body
Cytoplasm
Cytosol
Cytoplasmic Stress Granule
Membrane
RISC Complex
Intracellular Membrane-bounded Organelle
Molecular Function
RNA Helicase Activity
Helicase Activity
Protein Binding
ATP Binding
Protein Domain Specific Binding
Poly(A) RNA Binding
Biological Process
Positive Regulation Of Apoptotic Process
Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
Gene Expression
Cytoplasmic MRNA Processing Body Assembly
Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay
Pathways
mRNA decay by 5' to 3' exoribonuclease
Deadenylation-dependent mRNA decay
Drugs
Diseases
GWAS
Celiac disease and Rheumatoid arthritis (
21383967
)
Vitiligo (
22951725
)
Protein-Protein Interactions
32 interactors:
AP1M1
ARPC4
C11orf49
CARD9
CCDC102B
CCNC
CDC23
CEP57L1
CETN2
DDX6
GLIPR2
GORASP2
GRB2
KPNA2
MOAP1
MYO15B
PNMA1
POLR3C
PRKAA1
PSMA1
RAD23B
SH3KBP1
TBC1D22B
TNPO2
TTC23
TXNL4B
VIM
VPS28
WDYHV1
ZBTB25
ZFYVE26
ZMYND19
24 interactors:
AES
BEND7
BIRC7
CALCOCO2
CEP70
EDC3
EIF4ENIF1
GOLGA2
IKZF1
KRT40
KRTAP10-3
KRTAP10-8
NONO
PNMA5
RUNDC3A
SDCCAG3
SRPK2
TCF4
TRIM27
TRIM37
U2AF2
VPS52
ZBTB8A
ZNF24
Entrez ID
114824
1656
HPRD ID
06678
02638
Ensembl ID
ENSG00000198883
Uniprot IDs
Q96PV4
B2R858
P26196
PDB IDs
1VEC
2WAX
2WAY
Enriched GO Terms of Interacting Partners
?
Organelle Organization
Viral Process
Negative Regulation Of Protein Ubiquitination
Cellular Response To DNA Damage Stimulus
Enzyme Linked Receptor Protein Signaling Pathway
Cell Cycle
Response To Stress
Cell Cycle Process
Negative Regulation Of Glucosylceramide Biosynthetic Process
Cold Acclimation
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Cellular Response To Stress
Negative Regulation Of ERBB Signaling Pathway
Mitotic Cell Cycle
Regulation Of Protein Ubiquitination
Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition
Nucleotide-excision Repair, DNA Damage Recognition
Ubiquitin-dependent Protein Catabolic Process
Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Negative Regulation Of Ubiquitin-protein Transferase Activity
Modification-dependent Protein Catabolic Process
Cellular Macromolecule Catabolic Process
Positive Regulation Of Signal Transduction
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Positive Regulation Of Ubiquitin-protein Transferase Activity
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
Proteolysis Involved In Cellular Protein Catabolic Process
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Protein Targeting To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
Negative Regulation Of Glucose Import In Response To Insulin Stimulus
Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Cellular Protein Localization
Positive Regulation Of Ligase Activity
Regulation Of Cell Cycle
Cellular Protein Catabolic Process
Regulation Of ERBB Signaling Pathway
Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Response To Camptothecin
Protein Insertion Into Mitochondrial Membrane
Regulation Of Ubiquitin-protein Transferase Activity
Protein Catabolic Process
Regulation Of MAPK Cascade
Regulation Of Cellular Component Organization
Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Signal Transduction In Response To DNA Damage
Nucleotide-excision Repair
Negative Regulation Of Gene Expression
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Cellular Metabolic Process
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Biosynthetic Process
RNA Metabolic Process
Gene Expression
Regulation Of Protein Binding
Transcription, DNA-templated
Negative Regulation Of Transcription From RNA Polymerase II Promoter
RNA Biosynthetic Process
Embryonic Digestive Tract Development
Regulation Of Nitrogen Compound Metabolic Process
MRNA Metabolic Process
Regulation Of Apoptotic Process
Positive Regulation Of Neutrophil Differentiation
Nuclear Speck Organization
Regulation Of Natural Killer Cell Apoptotic Process
Negative Regulation Of Protein Binding
Regulation Of Cell Death
Regulation Of Binding
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Regulation Of RNA Metabolic Process
Regulation Of MRNA Splicing, Via Spliceosome
Positive Regulation Of Cell Death
Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Interleukin-2 Secretion
Catenin Import Into Nucleus
Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition
Embryonic Ectodermal Digestive Tract Development
Negative Regulation Of Viral Process
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process
Histone H2A-K119 Monoubiquitination
Regulation Of MRNA Processing
RNA Splicing
Regulation Of Gene Expression
Negative Regulation Of Binding
Regulation Of RNA Splicing
Maintenance Of DNA Repeat Elements
Positive Regulation Of Anoikis
Cellular Nitrogen Compound Metabolic Process
Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway
Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Ectodermal Cell Differentiation
Negative Regulation Of Type B Pancreatic Cell Apoptotic Process
Tagcloud
?
concerted
contain
continuum
cpeb
dendritic
dormant
engaged
fmrp
foci
fus
granules
hud
masked
messengers
mrnas
polysomes
pumilio
rbps
repressed
smaug
stalled
staufen
synapse
thousands
tls
transcriptome
translational
trapped
zbp1
Tagcloud (Difference)
?
concerted
contain
continuum
cpeb
dendritic
dormant
engaged
fmrp
foci
fus
granules
hud
masked
messengers
mrnas
polysomes
pumilio
rbps
repressed
smaug
stalled
staufen
synapse
thousands
tls
transcriptome
translational
trapped
zbp1
Tagcloud (Intersection)
?