PNMA5 and POLR3C

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		PNMA5	POLR3C
Gene Name		paraneoplastic Ma antigen family member 5	polymerase (RNA) III (DNA directed) polypeptide C (62kD)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component		Nucleus Nucleoplasm DNA-directed RNA Polymerase III Complex Cytosol
	Molecular Function		RNA Polymerase III Activity DNA Binding DNA-directed RNA Polymerase Activity
	Biological Process	Positive Regulation Of Apoptotic Process	Regulation Of Transcription From RNA Polymerase III Promoter Transcription From RNA Polymerase III Promoter Transcription Elongation From RNA Polymerase III Promoter Termination Of RNA Polymerase III Transcription Gene Expression Positive Regulation Of Type I Interferon Production Positive Regulation Of Interferon-beta Production Innate Immune Response Positive Regulation Of Innate Immune Response Defense Response To Virus
Pathways			RNA Polymerase III Transcription Termination RNA Polymerase III Transcription RNA Polymerase III Transcription Initiation RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase III Abortive And Retractive Initiation Cytosolic sensors of pathogen-associated DNA RNA Polymerase III Chain Elongation RNA Polymerase III Transcription Initiation From Type 2 Promoter Innate Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		32 interactors: AP1M1 ARPC4 C11orf49 CARD9 CCDC102B CCNC CDC23 CEP57L1 CETN2 DDX6 GLIPR2 GORASP2 GRB2 KPNA2 MOAP1 MYO15B PNMA1 POLR3C PRKAA1 PSMA1 RAD23B SH3KBP1 TBC1D22B TNPO2 TTC23 TXNL4B VIM VPS28 WDYHV1 ZBTB25 ZFYVE26 ZMYND19	8 interactors: APP CEP63 GTF3C4 PNMA5 ROCK1 ROPN1 TNR TRIM27
Entrez ID		114824	10623
HPRD ID		06678	17880
Ensembl ID		ENSG00000198883	ENSG00000186141
Uniprot IDs		Q96PV4	Q9BUI4
PDB IDs			2XUB 2XV4
Enriched GO Terms of Interacting Partners?		Organelle Organization Viral Process Negative Regulation Of Protein Ubiquitination Cellular Response To DNA Damage Stimulus Enzyme Linked Receptor Protein Signaling Pathway Cell Cycle Response To Stress Cell Cycle Process Negative Regulation Of Glucosylceramide Biosynthetic Process Cold Acclimation Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Cellular Response To Stress Negative Regulation Of ERBB Signaling Pathway Mitotic Cell Cycle Regulation Of Protein Ubiquitination Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Nucleotide-excision Repair, DNA Damage Recognition Ubiquitin-dependent Protein Catabolic Process Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Ubiquitin-protein Transferase Activity Modification-dependent Protein Catabolic Process Cellular Macromolecule Catabolic Process Positive Regulation Of Signal Transduction Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Proteolysis Involved In Cellular Protein Catabolic Process Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Protein Targeting To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Negative Regulation Of Glucose Import In Response To Insulin Stimulus Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Cellular Protein Localization Positive Regulation Of Ligase Activity Regulation Of Cell Cycle Cellular Protein Catabolic Process Regulation Of ERBB Signaling Pathway Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Response To Camptothecin Protein Insertion Into Mitochondrial Membrane Regulation Of Ubiquitin-protein Transferase Activity Protein Catabolic Process Regulation Of MAPK Cascade Regulation Of Cellular Component Organization Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Signal Transduction In Response To DNA Damage Nucleotide-excision Repair	Axon Guidance Neuromuscular Process Controlling Balance Associative Learning Negative Regulation Of Axon Extension Involved In Regeneration Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Negative Regulation Of Interleukin-2 Secretion Synaptic Growth At Neuromuscular Junction Neuromuscular Process Neuron Projection Morphogenesis Learning Collateral Sprouting In Absence Of Injury Cell Morphogenesis Involved In Differentiation Synapse Organization Cellular Component Assembly Neuron Projection Development Negative Regulation Of Neuron Differentiation Collateral Sprouting Axon Midline Choice Point Recognition Membrane To Membrane Docking Cell Projection Morphogenesis Cell Part Morphogenesis 5S Class RRNA Transcription From RNA Polymerase III Type 1 Promoter TRNA Transcription From RNA Polymerase III Promoter Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Negative Regulation Of Calcium Ion Import Apical Constriction Axon Choice Point Recognition TRNA Transcription Locomotory Behavior Neuron Development Negative Regulation Of Axon Regeneration Positive Regulation Of Transmission Of Nerve Impulse Interferon-gamma Secretion Learning Or Memory Neuron Remodeling Cell Morphogenesis Bleb Assembly Regulation Of Developmental Growth Negative Regulation Of Neurogenesis Cognition Cytoskeleton Organization Neuron Differentiation Cell Projection Organization Regulation Of Transmission Of Nerve Impulse Centriole Replication Locomotory Exploration Behavior Positive Regulation Of Cellular Component Biogenesis
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