PNMA5 and CETN2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		PNMA5	CETN2
Description		PNMA family member 5	centrin 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus Nuclear Envelope Nuclear Pore Nucleoplasm Cytoplasm Centrosome Centriole Cytosol Cytoskeleton Cilium Photoreceptor Connecting Cilium Ciliary Basal Body Nuclear Pore Nuclear Basket Apical Part Of Cell Transcription Export Complex 2 XPC Complex Glial Cell Projection 9+2 Motile Cilium
	Molecular Function	Protein Binding Identical Protein Binding	Calcium Ion Binding Protein Binding Microtubule Binding G-protein Beta/gamma-subunit Complex Binding Heterotrimeric G-protein Binding Metal Ion Binding
	Biological Process	Positive Regulation Of Apoptotic Process	Microtubule Cytoskeleton Organization Mitotic Cell Cycle DNA Repair Nucleotide-excision Repair DNA Damage Response Centriole Replication Spermatogenesis Protein Transport Regulation Of Cytokinesis MRNA Transport Cell Division
Pathways			Regulation of PLK1 Activity at G2/M Transition SUMOylation of DNA damage response and repair proteins Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane DNA Damage Recognition in GG-NER Formation of Incision Complex in GG-NER AURKA Activation by TPX2
Drugs
Diseases
GWAS			Serum alkaline phosphatase levels ( 33339817)
Interacting Genes		59 interacting genes: AP1M1 APPL1 ARPC4 CADPS CARD9 CCDC102B CCNC CDC23 CEP57L1 CETN2 CRACR2A CSTPP1 CTNNA3 DDX6 DRC4 DZIP1L EHHADH FOXH1 FSD2 GLIPR2 GOLGA6L9 GORASP2 GPRASP3 GRB2 GYS1 HOOK3 HSF2BP KIF9 KIFC3 KPNA2 LHX3 LNX1 MAGED1 MOAP1 MYO15B NTAQ1 PAX5 PNKP PNMA1 POLR3C PRKAA1 PSMA1 RAD23B SH3KBP1 SORBS3 SPG21 TBC1D22B TCEA2 TCEANC TNPO2 TTC23 TXNL4B UBASH3A VIM VPS28 ZBTB25 ZFYVE26 ZMYND19 ZRANB1	7 interacting genes: ARSA CCP110 PNMA5 PRMT6 SFI1 UBC XPC
Entrez ID		114824	1069
HPRD ID		06678	02051
Ensembl ID		ENSG00000198883	ENSG00000147400
Uniprot IDs		Q96PV4	P41208
PDB IDs			1M39 1ZMZ 2A4J 2GGM 2K2I 2OBH 8EBS 8EBT 8EBV 8EBW 8EBX 8J07
Enriched GO Terms of Interacting Partners?		XPC Complex Cytoskeleton Protein Binding Cytoplasm
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