C14orf1 and CCDC106

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		C14orf1	CCDC106
Gene Name		chromosome 14 open reading frame 1	coiled-coil domain containing 106
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Membrane Transport Vesicle	Nucleus Nucleoplasm Nucleolus Cytoplasm
	Molecular Function	Molecular_function	Protein Binding
	Biological Process	Biological_process Sterol Biosynthetic Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		62 interactors: ALDH2 ANXA1 ANXA7 BAIAP2 BID BTBD2 CCDC106 CCL18 CDC42 CDK5RAP2 CELF3 CLN8 COX17 CRADD CREB1 CSTF2 DYNLL1 FAS FCGR2B FXR1 GADD45A GSK3B HMGB1 HNRNPH3 HNRNPUL1 HSPE1 HYLS1 KLHL20 LSM2 MAPK8IP2 MPHOSPH6 MRPL38 MRPS12 NAT9 NDUFA4L2 NR1H2 NSF PAFAH1B3 PCDHA4 PEX2 PFN1 PHYHIP POLE2 POLR2C POLR3F PPP1R8 PQBP1 RAB27A RPS6KA6 S100A8 SAT1 SEPHS1 SERPINB9 SNRPB SNRPG SULT1E1 TFG TK1 TSC22D1 TTR ZFP64 ZNF24	13 interactors: APP ATF4 C14orf1 COPS6 CRMP1 EEF1G FAM9B KAT5 LRIF1 RBM48 SETDB1 TP53 UTP14A
Entrez ID		11161	29903
HPRD ID		05201	09995
Ensembl ID
Uniprot IDs		Q6FII3 Q86TW5 Q9UKR5	Q9BWC9
PDB IDs
Enriched GO Terms of Interacting Partners?		MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Splicing Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death MRNA Processing Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process MRNA Metabolic Process Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Cysteine-type Endopeptidase Activity Nervous System Development Regulation Of Cysteine-type Endopeptidase Activity RNA Processing Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Endopeptidase Activity Regulation Of Apoptotic Process Positive Regulation Of Peptidase Activity Cellular Metabolic Process Regulation Of Cell Death Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Proteolysis Activation Of Cysteine-type Endopeptidase Activity Nucleobase-containing Compound Metabolic Process Anatomical Structure Development Response To Stress Regulation Of Catalytic Activity Zymogen Activation Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Proteolysis Positive Regulation Of Apoptotic Signaling Pathway Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Developmental Process Nitrogen Compound Metabolic Process Response To External Stimulus Apoptotic Process Metabolic Process Programmed Cell Death Regulation Of Metabolic Process Regulation Of Cellular Component Organization Cell Death Death Cellular Response To Mechanical Stimulus DNA-templated Transcription, Termination System Development Regulation Of Endopeptidase Activity Immune Response Positive Regulation Of Catalytic Activity Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway	DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator DNA Damage Response, Signal Transduction Resulting In Transcription Cellular Response To Glucose Starvation RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Gene Expression Neuron Apoptotic Process Positive Regulation Of Neuron Apoptotic Process Cellular Nitrogen Compound Metabolic Process Neuron Death Positive Regulation Of Neuron Death DNA Damage Response, Signal Transduction By P53 Class Mediator Nitrogen Compound Metabolic Process Signal Transduction In Response To DNA Damage Response To External Stimulus Response To Oxidative Stress Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Macromitophagy Synaptic Growth At Neuromuscular Junction Oligodendrocyte Apoptotic Process Response To Radiation ER-nucleus Signaling Pathway Signal Transduction By P53 Class Mediator Positive Regulation Of Cellular Protein Metabolic Process Growth Cellular Metabolic Process Negative Regulation Of Helicase Activity Collateral Sprouting In Absence Of Injury Sterol Metabolic Process Positive Regulation Of Protein Metabolic Process Viral Process Cellular Response To Starvation Notch Signaling Pathway Response To Ionizing Radiation Double-strand Break Repair Biosynthetic Process Collateral Sprouting Axon Midline Choice Point Recognition Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress Positive Regulation Of Transcription, DNA-templated Transcription, DNA-templated Regulation Of Growth Response To Endoplasmic Reticulum Stress Metabolic Process Positive Regulation Of Thymocyte Apoptotic Process Positive Regulation Of Cell Aging Smooth Endoplasmic Reticulum Calcium Ion Homeostasis
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