ERG28 and STOM

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ERG28	STOM
Description		ergosterol biosynthesis 28 homolog	stomatin
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Transport Vesicle	Extracellular Space Cytoplasm Mitochondrion Endoplasmic Reticulum Cytosol Cytoskeleton Plasma Membrane Membrane Cytoplasmic Vesicle Vesicle Azurophil Granule Membrane Specific Granule Membrane Melanosome Membrane Raft Perinuclear Region Of Cytoplasm Extracellular Exosome Tertiary Granule Membrane Blood Microparticle
	Molecular Function	Protein Binding Protein-macromolecule Adaptor Activity Identical Protein Binding	Protein Binding Ion Channel Inhibitor Activity Identical Protein Binding Protein Homodimerization Activity RNA Polymerase Binding
	Biological Process	Lipid Metabolic Process Steroid Biosynthetic Process Steroid Metabolic Process Sterol Biosynthetic Process	Regulation Of Monoatomic Ion Transmembrane Transport Host-mediated Activation Of Viral Genome Replication Positive Regulation Of Viral Process Positive Regulation Of Protein Targeting To Membrane
Pathways			Stimuli-sensing channels Neutrophil degranulation RHOA GTPase cycle RHOB GTPase cycle RHOC GTPase cycle CDC42 GTPase cycle RHOQ GTPase cycle RHOH GTPase cycle RHOJ GTPase cycle
Drugs
Diseases			Hereditary stomatocytosis (HSt); Dehydrated hereditary stomatocytosis (DHS); Overhydrated hereditary stomatocytosis (OHS); Familial pseudohyperkalemia (FP)
GWAS
Interacting Genes		127 interacting genes: ALDH2 ANXA1 ANXA7 AQP2 AQP3 AQP6 ARL13B BAIAP2 BCL2L13 BID BTBD2 CCDC106 CCL18 CD53 CD74 CDC42 CDK5RAP2 CELF3 CLDN5 CLDN7 CLN8 COX17 COXFA4L2 CRADD CREB1 CREB3 CREB3L1 CSTF2 CYB561 DYNLL1 EBP ELOVL4 ERBB2 ERBB3 ERBB4 ERGIC3 FAM174A FAM209A FAS FCGR2B FFAR2 FXR1 FXYD3 GADD45A GET1 GJB5 GPR152 GPR37L1 GPR42 GPX8 GSK3B HMGB1 HNRNPH3 HNRNPUL1 HSD17B11 HSPE1 HTR2C HYLS1 JAGN1 KCNJ6 KLHL20 LHFPL5 LMNA LSM2 LYPD5 MAPK8IP2 MGST3 MPHOSPH6 MRM1 MRPL38 MRPS12 MS4A3 MSMO1 MTERF3 MTNR1B MUC1 NAT9 NCR3LG1 NDUFA3 NR1H2 NSDHL NSF PAFAH1B3 PCDHA4 PDZK1IP1 PEX2 PFN1 PHYHIP PIGY POLE2 POLR2C POLR3F PPP1R8 PQBP1 PSCA RAB27A REEP4 RETREG3 RPS6KA6 S100A8 SAR1A SAT1 SEPHS1 SERPINB9 SGPL1 SLC10A6 SLC26A6 SLC34A2 SLC71A2 SNRPB SNRPG SSMEM1 STOM STX1A SULT1E1 TFG TK1 TLCD4 TM4SF19 TMEM106A TMEM222 TMEM31 TMPRSS2 TSC22D1 TTR ZFP64 ZNF24	81 interacting genes: AIG1 APOA2 ASIC1 ASIC2 ASIC3 ATP1B3 ATP6V0B ATP6V0C BCL2L2 BNIP1 C2 C3orf52 CFHR5 CHST1 CLDN19 CLRN2 CMTM5 CNIH3 CTXN3 CYB5B CYB5R3 DAGLA DVL3 EMP1 ERG28 FAXDC2 FUNDC2 GIMAP1 GIMAP5 GPR25 GPR37L1 GRM2 HMOX2 KCNK1 KTN1 LANCL1 LNPEP MGLL MMP14 NKG7 ORMDL1 PEDS1-UBE2V1 PEMT PGA4 PMP22 PTCH1 RPL13A RPRM RTP2 RUVBL1 RUVBL2 SCD SELENOK SERP2 SFT2D1 SFT2D2 SFXN1 SFXN5 SLC2A1 SLC35B4 SMCO4 STX6 TECR THSD7B TMEM109 TMEM120B TMEM140 TMEM14B TMEM203 TMEM208 TMEM254 TMEM60 TMEM86B TMEM98 TMPO TNF TNFRSF10C TSPO2 VAMP4 WFDC2 YIPF6
Entrez ID		11161	2040
HPRD ID		05201	00585
Ensembl ID		ENSG00000133935	ENSG00000148175
Uniprot IDs		Q6FII3 Q86TW5 Q9UKR5	F8VSL7 P27105
PDB IDs			7WH3
Enriched GO Terms of Interacting Partners?		Protein Binding Membrane Identical Protein Binding Negative Regulation Of Apoptotic Process Renal Water Transport Negative Regulation Of Programmed Cell Death Regulation Of Apoptotic Signaling Pathway Polyol Transmembrane Transport Regulation Of Apoptotic Process Positive Regulation Of Cardiac Muscle Tissue Development ERBB3:ERBB2 Complex Regulation Of Secretion Regulation Of Programmed Cell Death Endoplasmic Reticulum Membrane Regulation Of MAPK Cascade Fluid Transport Water Channel Activity Positive Regulation Of MAPK Cascade Positive Regulation Of Viral Entry Into Host Cell Neuregulin Receptor Activity Regulation Of Transport Negative Regulation Of Hemopoiesis Negative Regulation Of Secretion Apolipoprotein A-I Receptor Binding Regulation Of Protein-containing Complex Assembly Negative Regulation Of Apoptotic Signaling Pathway Negative Regulation Of Peptide Secretion Apical Plasma Membrane Positive Regulation Of Transport	Membrane Endoplasmic Reticulum Membrane Sensory Perception Of Sour Taste Endoplasmic Reticulum Response To Acidic PH Sodium Channel Activity PH-gated Sodium Channel Activity Monoatomic Ion-gated Channel Activity Ligand-gated Sodium Channel Activity Protein Binding Cellular Response To Type II Interferon Response To PH PH-gated Monoatomic Ion Channel Activity Nitric-oxide Synthase Complex Synaptic Vesicle To Endosome Fusion Mitochondrial Outer Membrane Response To Type II Interferon Proton-transporting Two-sector ATPase Complex, Proton-transporting Domain Nitrite Reductase (NO-forming) Activity R2TP Complex Cellular Response To PH Detection Of Mechanical Stimulus Involved In Sensory Perception Acylglycerol Catabolic Process Diacylglycerol Catabolic Process Lipid Biosynthetic Process Amino Acid Transport Organic Anion Transport Telomerase RNA Localization To Cajal Body Sensory Perception Of Taste Response To Mechanical Stimulus Plasma Membrane
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