C14orf1 and COX17

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		C14orf1	COX17
Gene Name		chromosome 14 open reading frame 1	COX17 cytochrome c oxidase copper chaperone
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Membrane Transport Vesicle	Cytoplasm Mitochondrion Mitochondrial Intermembrane Space
	Molecular Function	Molecular_function	Copper Ion Binding Copper Chaperone Activity
	Biological Process	Biological_process Sterol Biosynthetic Process	Generation Of Precursor Metabolites And Energy Copper Ion Transport Brain Development Heart Development
Pathways			Mitochondrial protein import
Drugs
Diseases
GWAS
Protein-Protein Interactions		62 interactors: ALDH2 ANXA1 ANXA7 BAIAP2 BID BTBD2 CCDC106 CCL18 CDC42 CDK5RAP2 CELF3 CLN8 COX17 CRADD CREB1 CSTF2 DYNLL1 FAS FCGR2B FXR1 GADD45A GSK3B HMGB1 HNRNPH3 HNRNPUL1 HSPE1 HYLS1 KLHL20 LSM2 MAPK8IP2 MPHOSPH6 MRPL38 MRPS12 NAT9 NDUFA4L2 NR1H2 NSF PAFAH1B3 PCDHA4 PEX2 PFN1 PHYHIP POLE2 POLR2C POLR3F PPP1R8 PQBP1 RAB27A RPS6KA6 S100A8 SAT1 SEPHS1 SERPINB9 SNRPB SNRPG SULT1E1 TFG TK1 TSC22D1 TTR ZFP64 ZNF24	10 interactors: C14orf1 COPS6 EEF1A1 HADHB KATNAL1 LRIF1 PPBP RBM48 TP53 UNC119
Entrez ID		11161	10063
HPRD ID		05201	05314
Ensembl ID
Uniprot IDs		Q6FII3 Q86TW5 Q9UKR5	Q14061
PDB IDs			2L0Y 2LGQ 2RN9 2RNB
Enriched GO Terms of Interacting Partners?		MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Splicing Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death MRNA Processing Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process MRNA Metabolic Process Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Cysteine-type Endopeptidase Activity Nervous System Development Regulation Of Cysteine-type Endopeptidase Activity RNA Processing Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Endopeptidase Activity Regulation Of Apoptotic Process Positive Regulation Of Peptidase Activity Cellular Metabolic Process Regulation Of Cell Death Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Proteolysis Activation Of Cysteine-type Endopeptidase Activity Nucleobase-containing Compound Metabolic Process Anatomical Structure Development Response To Stress Regulation Of Catalytic Activity Zymogen Activation Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Proteolysis Positive Regulation Of Apoptotic Signaling Pathway Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Developmental Process Nitrogen Compound Metabolic Process Response To External Stimulus Apoptotic Process Metabolic Process Programmed Cell Death Regulation Of Metabolic Process Regulation Of Cellular Component Organization Cell Death Death Cellular Response To Mechanical Stimulus DNA-templated Transcription, Termination System Development Regulation Of Endopeptidase Activity Immune Response Positive Regulation Of Catalytic Activity Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Tagcloud ?			affecting alleles appear budding cerevisae connection deadenylation decapping decay defective degradation dhh1 edc1 initiated machinery mrnas multicopy pat1 pat1delta promote promoted ribosome saccharomyces stm1 stm1delta translation understand upstream working
Tagcloud (Difference) ?			affecting alleles appear budding cerevisae connection deadenylation decapping decay defective degradation dhh1 edc1 initiated machinery mrnas multicopy pat1 pat1delta promote promoted ribosome saccharomyces stm1 stm1delta translation understand upstream working
Tagcloud (Intersection) ?