ERG28 and HYLS1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ERG28	HYLS1
Description		ergosterol biosynthesis 28 homolog	HYLS1 centriolar and ciliogenesis associated
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Transport Vesicle	Nucleus Cytoplasm Centrosome Centriole Cytosol Cytoskeleton Plasma Membrane Cilium Cell Projection Non-motile Cilium
	Molecular Function	Protein Binding Protein-macromolecule Adaptor Activity Identical Protein Binding	Protein Binding
	Biological Process	Lipid Metabolic Process Steroid Biosynthetic Process Steroid Metabolic Process Sterol Biosynthetic Process	Cell Projection Organization Cilium Assembly
Pathways
Drugs
Diseases
GWAS			Breast cancer (survival) ( 25890600) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
Interacting Genes		127 interacting genes: ALDH2 ANXA1 ANXA7 AQP2 AQP3 AQP6 ARL13B BAIAP2 BCL2L13 BID BTBD2 CCDC106 CCL18 CD53 CD74 CDC42 CDK5RAP2 CELF3 CLDN5 CLDN7 CLN8 COX17 COXFA4L2 CRADD CREB1 CREB3 CREB3L1 CSTF2 CYB561 DYNLL1 EBP ELOVL4 ERBB2 ERBB3 ERBB4 ERGIC3 FAM174A FAM209A FAS FCGR2B FFAR2 FXR1 FXYD3 GADD45A GET1 GJB5 GPR152 GPR37L1 GPR42 GPX8 GSK3B HMGB1 HNRNPH3 HNRNPUL1 HSD17B11 HSPE1 HTR2C HYLS1 JAGN1 KCNJ6 KLHL20 LHFPL5 LMNA LSM2 LYPD5 MAPK8IP2 MGST3 MPHOSPH6 MRM1 MRPL38 MRPS12 MS4A3 MSMO1 MTERF3 MTNR1B MUC1 NAT9 NCR3LG1 NDUFA3 NR1H2 NSDHL NSF PAFAH1B3 PCDHA4 PDZK1IP1 PEX2 PFN1 PHYHIP PIGY POLE2 POLR2C POLR3F PPP1R8 PQBP1 PSCA RAB27A REEP4 RETREG3 RPS6KA6 S100A8 SAR1A SAT1 SEPHS1 SERPINB9 SGPL1 SLC10A6 SLC26A6 SLC34A2 SLC71A2 SNRPB SNRPG SSMEM1 STOM STX1A SULT1E1 TFG TK1 TLCD4 TM4SF19 TMEM106A TMEM222 TMEM31 TMPRSS2 TSC22D1 TTR ZFP64 ZNF24	2 interacting genes: ERG28 GOLGA2
Entrez ID		11161	219844
HPRD ID		05201	08148
Ensembl ID		ENSG00000133935	ENSG00000198331
Uniprot IDs		Q6FII3 Q86TW5 Q9UKR5	Q96M11
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Binding Membrane Identical Protein Binding Negative Regulation Of Apoptotic Process Renal Water Transport Negative Regulation Of Programmed Cell Death Regulation Of Apoptotic Signaling Pathway Polyol Transmembrane Transport Regulation Of Apoptotic Process Positive Regulation Of Cardiac Muscle Tissue Development ERBB3:ERBB2 Complex Regulation Of Secretion Regulation Of Programmed Cell Death Endoplasmic Reticulum Membrane Regulation Of MAPK Cascade Fluid Transport Water Channel Activity Positive Regulation Of MAPK Cascade Positive Regulation Of Viral Entry Into Host Cell Neuregulin Receptor Activity Regulation Of Transport Negative Regulation Of Hemopoiesis Negative Regulation Of Secretion Apolipoprotein A-I Receptor Binding Regulation Of Protein-containing Complex Assembly Negative Regulation Of Apoptotic Signaling Pathway Negative Regulation Of Peptide Secretion Apical Plasma Membrane Positive Regulation Of Transport	Positive Regulation Of Protein Glycosylation Golgi Cis Cisterna Regulation Of Protein Glycosylation Golgi Ribbon Formation Importin-alpha Family Protein Binding Golgi Disassembly Asymmetric Cell Division Meiotic Spindle Assembly Positive Regulation Of Glycoprotein Metabolic Process Positive Regulation Of Glycoprotein Biosynthetic Process Meiotic Spindle Organization Negative Regulation Of Protein Binding Regulation Of Glycoprotein Biosynthetic Process Syntaxin Binding COPII-coated ER To Golgi Transport Vesicle Regulation Of Protein Binding Centrosome Cycle Microtubule Nucleation Cis-Golgi Network Mitotic Spindle Assembly Sterol Biosynthetic Process Protein Homotetramerization Golgi Cisterna Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Mitotic Spindle Organization Organelle Disassembly Microtubule Organizing Center Organization Spindle Assembly Identical Protein Binding Protein Tetramerization Steroid Biosynthetic Process Negative Regulation Of Autophagy Transport Vesicle Golgi Organization Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Microtubule Cytoskeleton Organization Involved In Mitosis Sterol Metabolic Process
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