C14orf1 and POLR3F

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		C14orf1	POLR3F
Gene Name		chromosome 14 open reading frame 1	polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Membrane Transport Vesicle	Nucleoplasm DNA-directed RNA Polymerase III Complex Cytosol
	Molecular Function	Molecular_function	RNA Polymerase III Activity DNA Binding DNA-directed RNA Polymerase Activity Protein Binding
	Biological Process	Biological_process Sterol Biosynthetic Process	Regulation Of Transcription From RNA Polymerase III Promoter Transcription From RNA Polymerase III Promoter Transcription Elongation From RNA Polymerase III Promoter Termination Of RNA Polymerase III Transcription Gene Expression Positive Regulation Of Type I Interferon Production Positive Regulation Of Interferon-beta Production Innate Immune Response Positive Regulation Of Innate Immune Response Defense Response To Virus
Pathways			RNA Polymerase III Transcription Termination RNA Polymerase III Transcription RNA Polymerase III Transcription Initiation RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase III Abortive And Retractive Initiation Cytosolic sensors of pathogen-associated DNA RNA Polymerase III Chain Elongation RNA Polymerase III Transcription Initiation From Type 2 Promoter Innate Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		62 interactors: ALDH2 ANXA1 ANXA7 BAIAP2 BID BTBD2 CCDC106 CCL18 CDC42 CDK5RAP2 CELF3 CLN8 COX17 CRADD CREB1 CSTF2 DYNLL1 FAS FCGR2B FXR1 GADD45A GSK3B HMGB1 HNRNPH3 HNRNPUL1 HSPE1 HYLS1 KLHL20 LSM2 MAPK8IP2 MPHOSPH6 MRPL38 MRPS12 NAT9 NDUFA4L2 NR1H2 NSF PAFAH1B3 PCDHA4 PEX2 PFN1 PHYHIP POLE2 POLR2C POLR3F PPP1R8 PQBP1 RAB27A RPS6KA6 S100A8 SAT1 SEPHS1 SERPINB9 SNRPB SNRPG SULT1E1 TFG TK1 TSC22D1 TTR ZFP64 ZNF24	12 interactors: BDP1 BRF1 C14orf1 GTF3C4 KAT5 LRIF1 PRPF4B STC2 SUV39H2 TBP UBE2G2 WDR89
Entrez ID		11161	10621
HPRD ID		05201	15156
Ensembl ID			ENSG00000132664
Uniprot IDs		Q6FII3 Q86TW5 Q9UKR5	Q9H1D9
PDB IDs			2DK5 2YU3
Enriched GO Terms of Interacting Partners?		MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Splicing Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death MRNA Processing Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process MRNA Metabolic Process Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Cysteine-type Endopeptidase Activity Nervous System Development Regulation Of Cysteine-type Endopeptidase Activity RNA Processing Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Endopeptidase Activity Regulation Of Apoptotic Process Positive Regulation Of Peptidase Activity Cellular Metabolic Process Regulation Of Cell Death Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Proteolysis Activation Of Cysteine-type Endopeptidase Activity Nucleobase-containing Compound Metabolic Process Anatomical Structure Development Response To Stress Regulation Of Catalytic Activity Zymogen Activation Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Proteolysis Positive Regulation Of Apoptotic Signaling Pathway Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Developmental Process Nitrogen Compound Metabolic Process Response To External Stimulus Apoptotic Process Metabolic Process Programmed Cell Death Regulation Of Metabolic Process Regulation Of Cellular Component Organization Cell Death Death Cellular Response To Mechanical Stimulus DNA-templated Transcription, Termination System Development Regulation Of Endopeptidase Activity Immune Response Positive Regulation Of Catalytic Activity Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway	Transcription From RNA Polymerase III Promoter TRNA Transcription Transcription Initiation From RNA Polymerase III Promoter RNA Metabolic Process Transcription, DNA-templated Gene Expression Biosynthetic Process RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process RRNA Transcription DNA-templated Transcription, Initiation Nucleobase-containing Compound Metabolic Process Peptidyl-lysine Modification Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Peptidyl-amino Acid Modification Histone Modification Nitrogen Compound Metabolic Process Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Cellular Response To Oxygen Levels Histone Acetylation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Proepicardium Development Internal Protein Amino Acid Acetylation Cellular Protein Modification Process Protein Acetylation Negative Regulation Of Gene Expression Histone H3-K9 Dimethylation Chromatin Modification Regulation Of Gene Expression 5S Class RRNA Transcription From RNA Polymerase III Type 1 Promoter TRNA Transcription From RNA Polymerase III Promoter Placenta Development Chromatin Organization Histone H3-K9 Trimethylation Chorio-allantoic Fusion Peptidyl-lysine Dimethylation Regulation Of Metabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator Cellular Macromolecule Catabolic Process Proteasomal Protein Catabolic Process DNA Damage Response, Signal Transduction Resulting In Transcription Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process
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