C14orf1 and FCGR2B

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		C14orf1	FCGR2B
Gene Name		chromosome 14 open reading frame 1	Fc fragment of IgG, low affinity IIb, receptor (CD32)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Membrane Transport Vesicle	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Molecular_function	Protein Binding IgG Binding
	Biological Process	Biological_process Sterol Biosynthetic Process	Immune Response Signal Transduction Viral Process Regulation Of Immune Response
Pathways			Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Adaptive Immune System
Drugs
Diseases
GWAS			Inflammatory bowel disease ( 23128233) Lipid metabolism phenotypes ( 22286219) Ulcerative colitis ( 21297633)
Protein-Protein Interactions		62 interactors: ALDH2 ANXA1 ANXA7 BAIAP2 BID BTBD2 CCDC106 CCL18 CDC42 CDK5RAP2 CELF3 CLN8 COX17 CRADD CREB1 CSTF2 DYNLL1 FAS FCGR2B FXR1 GADD45A GSK3B HMGB1 HNRNPH3 HNRNPUL1 HSPE1 HYLS1 KLHL20 LSM2 MAPK8IP2 MPHOSPH6 MRPL38 MRPS12 NAT9 NDUFA4L2 NR1H2 NSF PAFAH1B3 PCDHA4 PEX2 PFN1 PHYHIP POLE2 POLR2C POLR3F PPP1R8 PQBP1 RAB27A RPS6KA6 S100A8 SAT1 SEPHS1 SERPINB9 SNRPB SNRPG SULT1E1 TFG TK1 TSC22D1 TTR ZFP64 ZNF24	11 interactors: APCS BLK C14orf1 CRP INPP5D INPPL1 LY6E LYN MAPK1 MAPK3 PTPN6
Entrez ID		11161	2213
HPRD ID		05201	06849
Ensembl ID			ENSG00000072694
Uniprot IDs		Q6FII3 Q86TW5 Q9UKR5	P31994
PDB IDs			2FCB
Enriched GO Terms of Interacting Partners?		MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Splicing Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death MRNA Processing Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process MRNA Metabolic Process Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Cysteine-type Endopeptidase Activity Nervous System Development Regulation Of Cysteine-type Endopeptidase Activity RNA Processing Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Endopeptidase Activity Regulation Of Apoptotic Process Positive Regulation Of Peptidase Activity Cellular Metabolic Process Regulation Of Cell Death Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Proteolysis Activation Of Cysteine-type Endopeptidase Activity Nucleobase-containing Compound Metabolic Process Anatomical Structure Development Response To Stress Regulation Of Catalytic Activity Zymogen Activation Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Proteolysis Positive Regulation Of Apoptotic Signaling Pathway Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Developmental Process Nitrogen Compound Metabolic Process Response To External Stimulus Apoptotic Process Metabolic Process Programmed Cell Death Regulation Of Metabolic Process Regulation Of Cellular Component Organization Cell Death Death Cellular Response To Mechanical Stimulus DNA-templated Transcription, Termination System Development Regulation Of Endopeptidase Activity Immune Response Positive Regulation Of Catalytic Activity Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway	JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway Growth Hormone Receptor Signaling Pathway Cellular Response To Growth Hormone Stimulus Immune Response-activating Cell Surface Receptor Signaling Pathway B Cell Receptor Signaling Pathway Response To Growth Hormone Antigen Receptor-mediated Signaling Pathway Positive Regulation Of Immune Response Immune Response-regulating Cell Surface Receptor Signaling Pathway JAK-STAT Cascade Immune Response Regulation Of Immune System Process Response To Peptide Hormone Immune System Process Immune Response-regulating Signaling Pathway Regulation Of Immune Response Response To Peptide Positive Regulation Of Immune System Process Wound Healing Cellular Response To Peptide Hormone Stimulus Cellular Response To Peptide Response To Wounding Defense Response Lipopolysaccharide-mediated Signaling Pathway Innate Immune Response Peptidyl-tyrosine Autophosphorylation Response To Organonitrogen Compound Blood Coagulation Hemostasis Regulation Of Golgi Inheritance Cellular Response To Organonitrogen Compound Platelet Activation Response To Hormone Negative Regulation Of Myeloid Leukocyte Differentiation Caveolin-mediated Endocytosis Regulation Of Cellular Localization Cellular Response To Heat Regulation Of Body Fluid Levels Negative Regulation Of Monocyte Differentiation Cellular Response To Hormone Stimulus Negative Regulation Of Lymphocyte Proliferation Negative Regulation Of Mononuclear Cell Proliferation Phagocytosis Regulation Of Golgi Organization Leukocyte Mediated Immunity Negative Regulation Of Leukocyte Proliferation Peptidyl-tyrosine Phosphorylation Endocytosis Response To Insulin Regulation Of MAP Kinase Activity
Tagcloud ?			arm arms benefit carriers concurrently deriving dfs equivocal fcgammar fcgr3a genotypes genotypic genotyping i232t igg1 killer log n9831 polymorphisms pooled portion proportional r131h rank sequentially superior trastuzumab v158f
Tagcloud (Difference) ?			arm arms benefit carriers concurrently deriving dfs equivocal fcgammar fcgr3a genotypes genotypic genotyping i232t igg1 killer log n9831 polymorphisms pooled portion proportional r131h rank sequentially superior trastuzumab v158f
Tagcloud (Intersection) ?