ERG28 and BTBD2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ERG28	BTBD2
Description		ergosterol biosynthesis 28 homolog	BTB domain containing 2
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Transport Vesicle	P-body Cytoplasm Cytosol
	Molecular Function	Protein Binding Protein-macromolecule Adaptor Activity Identical Protein Binding	Protein Binding
	Biological Process	Lipid Metabolic Process Steroid Biosynthetic Process Steroid Metabolic Process Sterol Biosynthetic Process	Neurogenesis
Pathways
Drugs
Diseases
GWAS			Mitochondrial DNA copy number (white blood cells) ( 30704525) Platelet count ( 27863252 32888494) Platelet distribution width ( 32888494) Plateletcrit ( 32888494)
Interacting Genes		127 interacting genes: ALDH2 ANXA1 ANXA7 AQP2 AQP3 AQP6 ARL13B BAIAP2 BCL2L13 BID BTBD2 CCDC106 CCL18 CD53 CD74 CDC42 CDK5RAP2 CELF3 CLDN5 CLDN7 CLN8 COX17 COXFA4L2 CRADD CREB1 CREB3 CREB3L1 CSTF2 CYB561 DYNLL1 EBP ELOVL4 ERBB2 ERBB3 ERBB4 ERGIC3 FAM174A FAM209A FAS FCGR2B FFAR2 FXR1 FXYD3 GADD45A GET1 GJB5 GPR152 GPR37L1 GPR42 GPX8 GSK3B HMGB1 HNRNPH3 HNRNPUL1 HSD17B11 HSPE1 HTR2C HYLS1 JAGN1 KCNJ6 KLHL20 LHFPL5 LMNA LSM2 LYPD5 MAPK8IP2 MGST3 MPHOSPH6 MRM1 MRPL38 MRPS12 MS4A3 MSMO1 MTERF3 MTNR1B MUC1 NAT9 NCR3LG1 NDUFA3 NR1H2 NSDHL NSF PAFAH1B3 PCDHA4 PDZK1IP1 PEX2 PFN1 PHYHIP PIGY POLE2 POLR2C POLR3F PPP1R8 PQBP1 PSCA RAB27A REEP4 RETREG3 RPS6KA6 S100A8 SAR1A SAT1 SEPHS1 SERPINB9 SGPL1 SLC10A6 SLC26A6 SLC34A2 SLC71A2 SNRPB SNRPG SSMEM1 STOM STX1A SULT1E1 TFG TK1 TLCD4 TM4SF19 TMEM106A TMEM222 TMEM31 TMPRSS2 TSC22D1 TTR ZFP64 ZNF24	37 interacting genes: BRD7 CCDC90B CCNC CDK2 CINP COPS6 CRMP1 CUL3 DPPA4 EEF1A1 ERG28 FXR1 GAPDH GBP2 GDF9 IGSF21 KPNA2 MLH1 NGB NTAQ1 OSGIN1 PSMD5 PTN RBM48 RUNX1 SETDB1 SMAD1 SMAD2 TDP2 TGFBR1 TLE1 TOP1 TP53 TRIM5 UBR1 UNC119 ZNF512B
Entrez ID		11161	55643
HPRD ID		05201	12252
Ensembl ID		ENSG00000133935	ENSG00000133243
Uniprot IDs		Q6FII3 Q86TW5 Q9UKR5	Q9BX70
PDB IDs			3NO8
Enriched GO Terms of Interacting Partners?		Protein Binding Membrane Identical Protein Binding Negative Regulation Of Apoptotic Process Renal Water Transport Negative Regulation Of Programmed Cell Death Regulation Of Apoptotic Signaling Pathway Polyol Transmembrane Transport Regulation Of Apoptotic Process Positive Regulation Of Cardiac Muscle Tissue Development ERBB3:ERBB2 Complex Regulation Of Secretion Regulation Of Programmed Cell Death Endoplasmic Reticulum Membrane Regulation Of MAPK Cascade Fluid Transport Water Channel Activity Positive Regulation Of MAPK Cascade Positive Regulation Of Viral Entry Into Host Cell Neuregulin Receptor Activity Regulation Of Transport Negative Regulation Of Hemopoiesis Negative Regulation Of Secretion Apolipoprotein A-I Receptor Binding Regulation Of Protein-containing Complex Assembly Negative Regulation Of Apoptotic Signaling Pathway Negative Regulation Of Peptide Secretion Apical Plasma Membrane Positive Regulation Of Transport	Male Germ Cell Nucleus Transforming Growth Factor Beta Receptor Signaling Pathway I-SMAD Binding Homomeric SMAD Protein Complex Positive Regulation Of Gene Expression Disordered Domain Specific Binding Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway Nucleoplasm Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway SMAD Protein Complex Trophoblast Cell Migration Peptidyl-serine Phosphorylation Heteromeric SMAD Protein Complex Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Transcription Regulator Complex Gastrulation Embryonic Cleavage Positive Regulation Of Biosynthetic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Nucleus Regulation Of Macromolecule Metabolic Process Regulation Of Protein Metabolic Process DNA-templated Transcription Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Female Gamete Generation Primary MiRNA Processing Co-SMAD Binding Mesenchyme Development Negative Regulation Of Long-term Synaptic Potentiation Negative Regulation Of Neuroblast Proliferation Negative Regulation Of Cell Cycle G1/S Phase Transition Positive Regulation Of Metabolic Process Regulation Of Primary Metabolic Process Positive Regulation Of Dendrite Development Ubiquitin Protein Ligase Binding Mitotic G1 DNA Damage Checkpoint Signaling Negative Regulation Of Macromolecule Biosynthetic Process Chromatin Binding Mitotic G1/S Transition Checkpoint Signaling Regulation Of MiRNA Transcription Cell Fate Commitment Negative Regulation Of RNA Metabolic Process Positive Regulation Of Multicellular Organismal Process Negative Regulation Of Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Metabolic Process DNA Metabolic Process Positive Regulation Of Type I Interferon Production Regulation Of MiRNA Metabolic Process
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