TLK2 and FEZ2

Number of citations of the paper that reports this interaction (PMID 16484223)
14

Data Source:
BioGRID (two hybrid)

		TLK2	FEZ2
Gene Name		tousled-like kinase 2	fasciculation and elongation protein zeta 2 (zygin II)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Intermediate Filament Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding	Protein Binding
	Biological Process	Regulation Of Chromatin Assembly Or Disassembly Protein Phosphorylation Cellular Response To DNA Damage Stimulus Cell Cycle Chromosome Segregation Negative Regulation Of Autophagy Chromatin Modification Peptidyl-serine Phosphorylation Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Intracellular Signal Transduction Cellular Response To Gamma Radiation	Signal Transduction Nervous System Development Axon Guidance
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		10 interactors: ASF1A ASF1B AURKA FEZ1 FEZ2 IRF4 IRF7 MBP TLK1 YWHAZ	18 interactors: BRD1 C16orf59 CLASP2 DRAP1 FEZ1 KPNA2 NEK1 PDCD7 PRKCZ RAB3GAP1 RAI14 SAP30L SCOC SMC3 TBC1D25 TLK2 WWC1 ZNF251
Entrez ID		11011	9637
HPRD ID		10527	09213
Ensembl ID			ENSG00000171055
Uniprot IDs		Q86UE8	Q9UHY8
PDB IDs
Enriched GO Terms of Interacting Partners?		Chromatin Modification Chromatin Organization DNA Replication-dependent Nucleosome Assembly Chromosome Organization Positive Regulation Of Interleukin-4 Production Regulation Of Interleukin-4 Production DNA Replication-independent Nucleosome Assembly Cell Differentiation Regulation Of Toll-like Receptor Signaling Pathway Regulation Of Cell Differentiation Positive Regulation Of Cytokine Production Regulation Of MyD88-independent Toll-like Receptor Signaling Pathway Negative Regulation Of Spindle Checkpoint Positive Regulation Of Interleukin-13 Biosynthetic Process Response To External Stimulus Organelle Localization Regulation Of Cellular Component Organization Organelle Organization Spindle Assembly Involved In Female Meiosis I Positive Regulation Of Interleukin-10 Biosynthetic Process MDA-5 Signaling Pathway Positive Regulation Of Interleukin-4 Biosynthetic Process Type I Interferon Signaling Pathway Cellular Response To Type I Interferon Response To Type I Interferon Regulation Of Cellular Process Response To Stress Nucleosome Assembly Gene Expression Interferon-gamma-mediated Signaling Pathway Regulation Of Cytokine Production Spindle Assembly Involved In Meiosis Defense Response To Nematode Interferon-beta Production Immune Response Transcription, DNA-templated Chromatin Assembly Defense Response Nucleosome Organization Interferon-alpha Production Negative Regulation Of Macrophage Apoptotic Process Golgi Reassembly Spindle Stabilization RNA Biosynthetic Process Cellular Response To Interferon-gamma Chromatin Assembly Or Disassembly Leukocyte Activation Involved In Immune Response Neuron Projection Morphogenesis Regulation Of MyD88-dependent Toll-like Receptor Signaling Pathway T-helper 17 Cell Lineage Commitment	Regulation Of Autophagy Regulation Of Metabolic Process Establishment Or Maintenance Of Cell Polarity Negative Regulation Of Autophagy Regulation Of Cellular Process Organelle Organization Regulation Of Autophagic Vacuole Maturation Regulation Of Calcium Ion-dependent Exocytosis Of Neurotransmitter Positive Regulation Of Glutamate Neurotransmitter Secretion In Response To Membrane Depolarization Regulation Of Excitatory Postsynaptic Membrane Potential Regulation Of Postsynaptic Membrane Potential Regulation Of Cellular Component Organization Mitotic Nuclear Division Positive Regulation Of Endoplasmic Reticulum Tubular Network Organization Positive Regulation Of Interleukin-13 Secretion Positive Regulation Of Interleukin-5 Secretion Cell Cycle Negative Regulation Of Cellular Metabolic Process Cellular Metabolic Process Cell Projection Morphogenesis Positive Regulation Of Interleukin-10 Secretion Positive Regulation Of T-helper 2 Cell Cytokine Production Establishment Of Protein Localization To Endoplasmic Reticulum Membrane Cell Part Morphogenesis Establishment Of Cell Polarity Positive Regulation Of Synaptic Transmission Membrane Depolarization Peptidyl-serine Phosphorylation Cell Division Regulation Of Organelle Organization Microtubule Cytoskeleton Organization Peptidyl-amino Acid Modification Positive Regulation Of MAPK Cascade Positive Regulation Of Rab GTPase Activity Regulation Of Rab GTPase Activity Regulation Of Rab Protein Signal Transduction Activation Of Phospholipase D Activity Negative Regulation Of DNA Endoreduplication Positive Regulation Of Glutamate Secretion Chromosome Organization Regulation Of Chromatin Assembly Or Disassembly Negative Regulation Of Hippo Signaling Response To Ionizing Radiation Cell Morphogenesis Regulation Of Intracellular Signal Transduction Positive Regulation Of Interleukin-13 Production Regulation Of Synaptic Plasticity Nucleobase-containing Compound Metabolic Process Positive Regulation Of Interleukin-5 Production Positive Regulation Of T Cell Cytokine Production
Tagcloud ?		asymmetric belonging cloned coefficient crystallization crystals cubic diffracting diffraction evolutionarily hetero homo homogeneity i4122 localize matthews namely oligomers p213 purification segregation solvent synchrotron tetragonal threonine tlk1 tlks tousled yielded
Tagcloud (Difference) ?		asymmetric belonging cloned coefficient crystallization crystals cubic diffracting diffraction evolutionarily hetero homo homogeneity i4122 localize matthews namely oligomers p213 purification segregation solvent synchrotron tetragonal threonine tlk1 tlks tousled yielded
Tagcloud (Intersection) ?