PAEP and IGSF21

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PAEP	IGSF21
Gene Name		progestagen-associated endometrial protein	immunoglobin superfamily, member 21
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region	Extracellular Region
	Molecular Function	Small Molecule Binding
	Biological Process	Transport Multicellular Organismal Development
Pathways
Drugs
Diseases
GWAS			Diabetic retinopathy ( 21441570) Erectile dysfunction and prostate cancer treatment ( 20932654)
Protein-Protein Interactions		11 interactors: A2M APP COPS6 EEF1A1 GRAMD3 IGSF21 LRIF1 PTPRC SMAD3 UBE2E1 XRCC6	32 interactors: ALDH2 ANXA3 ATF3 BCR BTBD2 CRCT1 DGKD EPB41L3 ERH ETHE1 GADD45A GIPC2 GSK3B GSTM4 HSPB1 KRAS MAD2L1BP NACA NREP PAEP PAFAH1B3 PCDHA4 PRMT1 PSMD11 RPP14 S100A8 SEPHS1 SERPINB9 SULT1E1 TMSB4X TRBV2 UBE2V2
Entrez ID		5047	84966
HPRD ID		01411	11309
Ensembl ID		ENSG00000122133	ENSG00000117154
Uniprot IDs		P09466	Q96ID5
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Protein Metabolic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Proteolysis Cell Activation Negative Regulation Of Catalytic Activity Positive Regulation Of Proteolysis Regulation Of Humoral Immune Response Regulation Of Cell Cycle Negative Regulation Of Proteolysis Negative Regulation Of Protein Processing Platelet Degranulation Regulation Of Endopeptidase Activity Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Processing Regulation Of Peptidase Activity Positive Regulation Of Transforming Growth Factor Beta3 Production Regulation Of Mitotic Cell Cycle Response To Abiotic Stimulus Positive Regulation Of Cellular Protein Metabolic Process Response To Radiation Regulation Of Protein Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Protein Metabolic Process Immunoglobulin Biosynthetic Process Synaptic Growth At Neuromuscular Junction Positive Regulation Of Hematopoietic Stem Cell Migration Negative Regulation Of Complement Activation, Lectin Pathway Protein Metabolic Process Negative Regulation Of Protein Catabolic Process Regulation Of Catalytic Activity Viral Process Negative Regulation Of Immune Response Cellular Hyperosmotic Salinity Response Collateral Sprouting In Absence Of Injury Evasion Or Tolerance Of Host Defenses By Virus Wound Healing Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Peptidase Activity Response To Ionizing Radiation Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway Positive Regulation Of Extracellular Matrix Assembly Positive Regulation Of Catalytic Activity Regulation Of Cell Differentiation Regulation Of Extracellular Matrix Assembly Collateral Sprouting Axon Midline Choice Point Recognition Immune System Development Response To Wounding Smooth Endoplasmic Reticulum Calcium Ion Homeostasis	Response To Wounding Regulation Of Apoptotic Process Regulation Of Cell Death Wound Healing Positive Regulation Of Protein Metabolic Process Response To Stress Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Negative Regulation Of Cell Death Negative Regulation Of Catalytic Activity Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Catalytic Activity Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Proteolysis Negative Regulation Of Transferase Activity Response To Stimulus Developmental Process Xenobiotic Metabolic Process Cellular Response To Xenobiotic Stimulus Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Response To Xenobiotic Stimulus Regulation Of Protein Metabolic Process Positive Regulation Of Cellular Protein Catabolic Process Apoptotic Process Epidermal Growth Factor Receptor Signaling Pathway Nervous System Development ERBB Signaling Pathway Regulation Of Proteolysis Programmed Cell Death Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Death Negative Regulation Of Transcription From RNA Polymerase II Promoter Involved In Heart Development Death Cellular Response To Stimulus Blood Coagulation Platelet Activation Hemostasis Regulation Of Protein Kinase Activity Response To Biotic Stimulus Multicellular Organismal Development Positive Regulation Of Catalytic Activity Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of Protein Kinase Activity Positive Regulation Of Rac GTPase Activity Positive Regulation Of Endothelial Cell Migration Regulation Of Neuronal Synaptic Plasticity Regulation Of Kinase Activity Positive Regulation Of Protein Catabolic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Growth
Tagcloud ?		acaca crh deregressed dgat1 fasn fertility fp fy gh1 holstein lep lgb longevity mastitis mfge8 milk mscc pft piebaldism positives pp ppargc1a proofs py relatedness sires thrsp tph1 traits
Tagcloud (Difference) ?		acaca crh deregressed dgat1 fasn fertility fp fy gh1 holstein lep lgb longevity mastitis mfge8 milk mscc pft piebaldism positives pp ppargc1a proofs py relatedness sires thrsp tph1 traits
Tagcloud (Intersection) ?